Problem Solving Process | List of Frontiers open access articles

Review

Published on 07 May 2026

An integrative neuropharmacological review of Huntington’s disease challenges and the role of novel formulations in addressing pharmacological‒pharmaceutical limitations

in Neuropharmacology

Mahmoud A. Senousy
Aya H. Eid
Mohamed Bakr Zaki
Mai A. Abd-Elmawla
Heba R. Ghaiad
Riham A. El-Shiekh
Sadek Ahmed
Hazim O. Khalifa

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1794983

281 views

Original Research

Published on 07 May 2026

Multicenter validation of a machine learning model for predicting intrapartum high fever in parturients receiving labor analgesia

in Intensive Care Medicine and Anesthesiology

Bo Liu
Liang Ling
Chunping Li
Siyan Dou
Jian Zhang
Fei Jia

Frontiers in Medicine

doi 10.3389/fmed.2026.1827290

226 views

Study Protocol

Published on 07 May 2026

Association between hypertension and risk of respiratory failure and mortality in patients with COVID-19: a retrospective cohort study with predictive model development

in Pulmonary Medicine

Xiaoqing Hu
Kailong Ye
Bifang Miao
Yiqun Dai
Lianghua Guo
Linmiao Zeng
Xiu Chen
Chuanqi Zhu
Qinghua Zhang
Bin Song

Frontiers in Medicine

doi 10.3389/fmed.2026.1825373

191 views

Original Research

Published on 07 May 2026

Hybrid Ant-Baby Optimizer and BiLSTM framework for high-performance IoT intrusion detection

in Machine Learning and Artificial Intelligence

Anbarasu Balakrishnan
Praveen Kumar Reddy Maddikunta

Frontiers in Artificial Intelligence

doi 10.3389/frai.2026.1795030

211 views

Original Research

Published on 07 May 2026

Passion and resilience in esports: the mediating role of passion in the relationship between weakness under pressure and resilience

in Sport Psychology

Nahit Ozdayi
Eda Ozkan
Alp Kaan Kilci

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1819430

275 views

Review

Published on 07 May 2026

Amyloid-β clearance: an astrocytic perspective

in Neurodegeneration

Jiayi Li
Zhongyue Lv
Xiao Chen
Fan Fu
Kaixia Yang
Guogang Lai
Hao Wu
Guomin Xie

Frontiers in Neuroscience

doi 10.3389/fnins.2026.1812081

250 views

Review

Published on 07 May 2026

Regulatory T cell therapy in solid organ transplantation: mechanisms, translational progress, and remaining barriers

in Alloimmunity and Transplantation

Jie Yang
Xusheng Zeng
Ke Jiang
Xiangli Pang
Ai Huang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1823841

379 views

Original Research

Published on 07 May 2026

Global pharmacovigilance reporting: comparative analysis of adverse event obligations across five major regulatory authorities

in Pharmaceutical Policy and Regulation

Carlos G. Bernaus
Maria Lilia Bournissen

Frontiers in Drug Safety and Regulation

doi 10.3389/fdsfr.2026.1821686

420 views

Original Research

Published on 07 May 2026

Recombinant TadZ from the type IVc pilus system induces protective immunity against virulent Aeromonas hydrophila in channel catfish (Ictalurus punctatus)

in Microbial Immunology

Young Kyung Park
Fenny Patel
Hossam Abdelhamed
Larry A. Hanson
Mark L. Lawrence
Hasan C. Tekedar

Frontiers in Immunology

doi 10.3389/fimmu.2026.1763508

240 views

Original Research

Published on 07 May 2026

Ameliorating social anxiety in rural left-behind children through line dance combined with multisensory stimulation

in Sport Psychology

Yiping Luo
Xiao Liu
Qian Yang
Jun Tao
Yuqin Sun
Weixin Dong
Jun Chen
Chunxia Lu

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1734053

204 views

Original Research

Published on 07 May 2026

Using ethical artificial intelligence (EAI) to achieve sustainable development, Iraq as a case study

in Modeling and Optimization for Decision Support

Rasha A. Waheeb
Bjørn S. Andersen
Kusay A. Wheib

Frontiers in Sustainability

doi 10.3389/frsus.2026.1737050

327 views

Original Research

Published on 07 May 2026

Impact of public assistance on long-term outcomes after hospitalization for acute heart failure

in Cardiovascular Epidemiology and Prevention

Takashi Morinaga
Masahiro Natsuaki
Akihiro Isotani
Kenji Kanenawa
Ko Yamamoto
Masato Fukunaga
Makoto Hyodo
Shinichi Shirai
Kenji Ando
Koichi Node

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1672844

189 views

Original Research

Published on 07 May 2026

Liver involvement in pediatric acute leukemia: subtype differences and complex hepatic injury as a novel marker for AML risk stratification

in Pediatric Oncology

Yu-juan Xue
Yu Wang
Ai-dong Lu
Yue-ping Jia
Zhi-xiao Zhang
Lin Zhang
Xiaoyu Cao
Le-ping Zhang
Hui-min Zeng

Frontiers in Oncology

doi 10.3389/fonc.2026.1749226

183 views

Original Research

Published on 07 May 2026

Molecular and morphological characteristics of Trichuris tenuis from South American Camelids bred in Europe

in Parasitology

Simona Rejnková
Ondřej Daněk
Ondřej Máca
David Modrý
Václava Hrabětová
Vincenzo Veneziano
Elisa Castaldo
Mikuláš Oros
Jiří Patoka
Zuzana Čadková

Frontiers in Veterinary Science

doi 10.3389/fvets.2026.1832113

227 views

Review

Published on 07 May 2026

Source-sink dynamics of coastal blue carbon: a review of mechanisms and drivers

in Coastal Ocean Processes

Meihong Ge
Jinfeng Du
Yunxiao Han
Lehong Chen
Xuefeng Xu
Yonglian Wang
Changbo Zhong
Dan Feng
Xiaoyan Wu

Frontiers in Marine Science

doi 10.3389/fmars.2026.1810020

245 views

Original Research

Published on 07 May 2026

A volume-controlled, anatomy-driven autoplanning strategy for whole-pelvic volumetric modulated arc therapy

in Radiation Oncology

Chih-Yuan Lin
An-Cheng Shiau
Ti-Hao Wang
Shih-Ming Hsu

Frontiers in Oncology

doi 10.3389/fonc.2026.1836562

228 views

Articles

An integrative neuropharmacological review of Huntington’s disease challenges and the role of novel formulations in addressing pharmacological‒pharmaceutical limitations

Multicenter validation of a machine learning model for predicting intrapartum high fever in parturients receiving labor analgesia

Association between hypertension and risk of respiratory failure and mortality in patients with COVID-19: a retrospective cohort study with predictive model development

Hybrid Ant-Baby Optimizer and BiLSTM framework for high-performance IoT intrusion detection

Passion and resilience in esports: the mediating role of passion in the relationship between weakness under pressure and resilience

Amyloid-β clearance: an astrocytic perspective

Regulatory T cell therapy in solid organ transplantation: mechanisms, translational progress, and remaining barriers

Global pharmacovigilance reporting: comparative analysis of adverse event obligations across five major regulatory authorities

Recombinant TadZ from the type IVc pilus system induces protective immunity against virulent Aeromonas hydrophila in channel catfish (Ictalurus punctatus)

Ameliorating social anxiety in rural left-behind children through line dance combined with multisensory stimulation

Using ethical artificial intelligence (EAI) to achieve sustainable development, Iraq as a case study

Impact of public assistance on long-term outcomes after hospitalization for acute heart failure

Liver involvement in pediatric acute leukemia: subtype differences and complex hepatic injury as a novel marker for AML risk stratification

Molecular and morphological characteristics of Trichuris tenuis from South American Camelids bred in Europe

Source-sink dynamics of coastal blue carbon: a review of mechanisms and drivers

A volume-controlled, anatomy-driven autoplanning strategy for whole-pelvic volumetric modulated arc therapy