Proteolytic Enzymes | List of Frontiers open access articles

Review

Published on 13 Feb 2026

Role of metabolic reprogramming and lactylation in diabetic nephropathy: molecular mechanisms and therapeutic prospects – a narrative review

in Diabetes: Molecular Mechanisms

Zongtao Li
Yashi Wang
Die Fang
Wenfeng Ye
Xueqin Zhang
Zhiqiang Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1770531

139 views

Review

Published on 13 Feb 2026

Current insights into monitoring of congenital adrenal hyperplasia

in Adrenal Endocrinology

Quinty M. Leusink
Elke E. W. Verploegen
Bas P. H. Adriaansen
Xinyi Chin
Nike M. M. L. Stikkelbroeck
Paul N. Span
Fred C. G. J. Sweep
Margo Dona
Antonius E. van Herwaarden
Hedi L. Claahsen-van der Grinten

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1774145

138 views

Case Report

Published on 13 Feb 2026

Minor trauma-induced eccrine porocarcinoma of the toe in a patient on long-term carbamazepine: a case report and literature review

in Skin Cancer

Lianbo Yang
Jinghang Lv
Xinghan Zhao
Ziang Zheng
Xinyao Cui
Jiabin Lin
Yifan Wang
Haidong Liang

Frontiers in Oncology

doi 10.3389/fonc.2026.1727762

115 views

Case Report

Published on 13 Feb 2026

Leptomeningeal metastasis from large-cell neuroendocrine carcinoma of the cervix: a case report and literature review

in Gynecological Oncology

Peng Xu
Zhen-Jiang Wang
Xin-Mei Dang
Bao-Yu Zhu
Zhang-Cai Zheng

Frontiers in Oncology

doi 10.3389/fonc.2026.1734305

133 views

Systematic Review

Published on 13 Feb 2026

Comparative efficacy of trastuzumab deruxtecan versus guideline-recommended treatments for 2L+ unresectable locally advanced or metastatic HER2-mutant non-small cell lung cancer: a systematic review and indirect treatment comparison

in Thoracic Oncology

Federico Cappuzzo
Lirong Zhang
Kyle Dunton
Natalie Dennis
Pauline Le Nouveau
Agathe Nevière
Aline Gauthier

Frontiers in Oncology

doi 10.3389/fonc.2025.1708245

284 views

Review

Published on 13 Feb 2026

Proximity extension assay-based targeted proteomics for biomarker discovery in adult bacterial infections

in Clinical and Diagnostic Microbiology and Immunology

Enrico Sguazzini
Carlo Montagna
Tarek Nayfeh
Martina Offer
Marta Colaneri
Francesco Petri
Cristina Banfi
Cecilia Bonazzetti
Andrea Gori
Matteo Passerini

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1716483

125 views

Original Research

Published on 13 Feb 2026

Addressing unmet needs in relapsed/refractory multiple myeloma: an Italian Delphi consensus on current challenges and emerging therapies

in Hematologic Malignancies

Michele Cavo
Sara Bringhen
Gabriele Buda
Francesco Di Raimondo
Pellegrino Musto
Massimo Offidani
Maria T. Petrucci
Elena Zamagni
Renato Zambello
Francesco Berruto

Frontiers in Oncology

doi 10.3389/fonc.2026.1756247

202 views

Original Research

Published on 13 Feb 2026

Epidemiology, clinical treatment and outcomes, susceptibility patterns and genotypic analysis of 214 Nocardia strains from multiple centers in Henan Province

in Antibiotic Resistance and New Antimicrobial drugs

Xiaogai Li
Cailin Liu
Yinyin Hu
Hui Xu
Haijun Li
Jingjing Sun
Xiangyang Chen
Yujuan Meng
Nan Zhang
Gongchang Li

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1728269

197 views

Editorial

Published on 13 Feb 2026

Editorial: HLA-G in health and disease: comprehensive insights and future therapeutic directions

in Immunological Tolerance and Regulation

Jules Russick
Roberta Rizzo
Ashwin Ajith

Frontiers in Immunology

doi 10.3389/fimmu.2026.1786277

Case Report

Published on 13 Feb 2026

Case Report: Hybrid low-grade fibromyxoid sarcoma and sclerosing epithelioid fibrosarcoma of the retroperitoneum

in Surgical Oncology

Zhandos Burkitbayev
Aruzhan Zhaksylyk
Baiduisen Ussipbekov
Talgat Uskenbayev
Altay Kerimkulov
Тomiris Sarina
Artem Gogolev
Saltanat Bolsinbekova
Aigerim Sipenova

Frontiers in Oncology

doi 10.3389/fonc.2026.1673104

199 views

Original Research

Published on 13 Feb 2026

Non-invasive wireless electroencephalographic recording of the sleep–wake cycle in freely moving reptiles, birds, and mammals: a novel methodology compatible with animal welfare

in Zoological Medicine

Mario Fernández-Sánchez
Carlos Barros-García
Miguel Garzón

Frontiers in Veterinary Science

doi 10.3389/fvets.2026.1736943

206 views

Original Research

Published on 13 Feb 2026

The role of pallidotomy in the precision medicine era

in Pediatric Neurology

Giacomo Garone
Alice Innocenti
Alessandro De Benedictis
Maria Camilla Rossi-Espagnet
Franco Randi
Donatella Lettori
Simone Reali
Flaminia Frascarelli
Alessandra Savioli
Silvia Cossu

Frontiers in Neurology

doi 10.3389/fneur.2026.1735969

138 views

Original Research

Published on 13 Feb 2026

Career commitment and sense of calling in nursing students: a longitudinal study

in Healthcare Professions Education

Tingting Ding
Jiaqi Shi
Wenjing Li
Feifei Xiong
Huihui Xu
Chengjia Zhao
Guohua Zhang
Chen Cong

Frontiers in Medicine

doi 10.3389/fmed.2026.1760650

Case Report

Published on 13 Feb 2026

The temporal sequence of myasthenia gravis and neuromyelitis optica spectrum disorder: a case report and systematic review of 74 patients

in Neuro-Ophthalmology

Zhenyu Niu
Yi Bao
Lanqiu Yao
Jingru Ren
Jianchun Wang
Jing Guo
Nan Zhang
Feng Gao
Hongjun Hao
Siwei Chen

Frontiers in Neurology

doi 10.3389/fneur.2026.1747855

196 views

Original Research

Published on 13 Feb 2026

TPX2 promotes gastric cancer progression and angiogenesis via Wnt/β-catenin signaling

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Li Xu
Weibo Zhang

Frontiers in Oncology

doi 10.3389/fonc.2026.1764583

Original Research

Published on 13 Feb 2026

Development and validation of a predictive model for pathological upgrading in colorectal polyps based on endoscopic forceps biopsy

in Pathology

Ziyao Cheng
Chang Zhang
Feng Yu

Frontiers in Medicine

doi 10.3389/fmed.2026.1748424

Articles

Role of metabolic reprogramming and lactylation in diabetic nephropathy: molecular mechanisms and therapeutic prospects – a narrative review

Current insights into monitoring of congenital adrenal hyperplasia

Minor trauma-induced eccrine porocarcinoma of the toe in a patient on long-term carbamazepine: a case report and literature review

Leptomeningeal metastasis from large-cell neuroendocrine carcinoma of the cervix: a case report and literature review

Comparative efficacy of trastuzumab deruxtecan versus guideline-recommended treatments for 2L+ unresectable locally advanced or metastatic HER2-mutant non-small cell lung cancer: a systematic review and indirect treatment comparison

Proximity extension assay-based targeted proteomics for biomarker discovery in adult bacterial infections

Addressing unmet needs in relapsed/refractory multiple myeloma: an Italian Delphi consensus on current challenges and emerging therapies

Epidemiology, clinical treatment and outcomes, susceptibility patterns and genotypic analysis of 214 Nocardia strains from multiple centers in Henan Province

Editorial: HLA-G in health and disease: comprehensive insights and future therapeutic directions

Case Report: Hybrid low-grade fibromyxoid sarcoma and sclerosing epithelioid fibrosarcoma of the retroperitoneum

Non-invasive wireless electroencephalographic recording of the sleep–wake cycle in freely moving reptiles, birds, and mammals: a novel methodology compatible with animal welfare

The role of pallidotomy in the precision medicine era

Career commitment and sense of calling in nursing students: a longitudinal study

The temporal sequence of myasthenia gravis and neuromyelitis optica spectrum disorder: a case report and systematic review of 74 patients

TPX2 promotes gastric cancer progression and angiogenesis via Wnt/β-catenin signaling

Development and validation of a predictive model for pathological upgrading in colorectal polyps based on endoscopic forceps biopsy