Pten Protein | List of Frontiers open access articles

Brief Research Report

Published on 09 Jun 2020

Icariin Attenuates Amyloid-β (Aβ)-Induced Neuronal Insulin Resistance Through PTEN Downregulation

in Neuropharmacology

Xiaomei Zou
Xiyao Feng
Yalin Fu
Yuyang Zheng
Mingke Ma
Changhua Wang
Yemin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00880

3,865 views
15 citations

Review

Published on 31 Jul 2024

Post-Translational Modification of PTEN Protein: Quantity and Activity

in Oncology Reviews: Reviews

Xiao Li
Pu Yang
Xiaoli Hou
Shaoping Ji

Oncology Reviews

doi 10.3389/or.2024.1430237

5,289 views
8 citations

Original Research

Published on 21 Jan 2020

Simultaneous Knockdown of Sprouty2 and PTEN Promotes Axon Elongation of Adult Sensory Neurons

in Cellular Neuropathology

Sataporn Jamsuwan
Lars Klimaschewski
Barbara Hausott

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2019.00583

5,562 views
13 citations

Review

Published on 01 Jun 2021

Phosphatase and Tensin Homolog in Non-neoplastic Digestive Disease: More Than Just Tumor Suppressor

in Gastrointestinal Sciences

Tianyu He
Xiaoyun Zhang
Jianyu Hao
Shigang Ding

Frontiers in Physiology

doi 10.3389/fphys.2021.684529

4,963 views
11 citations

Case Report

Published on 12 Jul 2022

Case Report: Duodenal Carcinoma in a 40-Year-Old Asian Man With Cowden Syndrome

in Surgical Oncology

Mingkun Zhao
Xiaohan Lin
Yuan Fang
Aobo Zhuang
Hanxing Tong
Weiqi Lu
Yuhong Zhou
Yong Zhang

Frontiers in Surgery

doi 10.3389/fsurg.2022.935048

4,388 views
3 citations

Original Research

Published on 03 Apr 2020

Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells

in Gastrointestinal and Hepatic Pharmacology

Shasha He
Yuhong Guo
Jingxia Zhao
Xiaolong Xu
Ning Wang
Qingquan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00376

14,873 views
76 citations

Review

Published on 16 Feb 2015

PTEN: Multiple Functions in Human Malignant Tumors

in Molecular and Cellular Oncology

Michele Milella
Italia Falcone
Fabiana Conciatori
Ursula Cesta Incani
Anais Del Curatolo
Nicola Inzerilli
Carmen M. A. Nuzzo
Vanja Vaccaro
Sabrina Vari
Francesco Cognetti

Frontiers in Oncology

doi 10.3389/fonc.2015.00024

46,145 views
426 citations

Original Research

Published on 20 Aug 2020

Activation of Type 4 Metabotropic Glutamate Receptor Regulates Proliferation and Neuronal Differentiation in a Cultured Rat Retinal Progenitor Cell Through the Suppression of the cAMP/PTEN/AKT Pathway

in Molecular Signalling and Pathways

Zhichao Zhang
Yingfei Liu
Yan Luan
Kun Zhu
Baoqi Hu
Bo Ma
Li Chen
Xuan Liu
Haixia Lu
Xinlin Chen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2020.00141

4,705 views
7 citations

Original Research

Published on 12 Feb 2021

iNOS Associates With Poor Survival in Melanoma: A Role for Nitric Oxide in the PI3K-AKT Pathway Stimulation and PTEN S-Nitrosylation

in Molecular and Cellular Oncology

Zhen Ding
Dai Ogata
Jason Roszik
Yong Qin
Sun-Hee Kim
Michael T. Tetzlaff
Alexander J. Lazar
Michael A. Davies
Suhendan Ekmekcioglu
Elizabeth A. Grimm

Frontiers in Oncology

doi 10.3389/fonc.2021.631766

5,592 views
37 citations

Original Research

Published on 30 Jul 2025

Mechanism of action of decitabine in treating acute lymphoblastic leukemia

in Hematology

Xiaohui Gao
Hui Zeng
Fei Sun
Xiaoyan Zhao
Haibing Wu
Minchao Yan
Yuan Li
Qinyan Fu
Gang Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1614592

2,397 views

Systematic Review

Published on 18 Sep 2018

The Role of Immunohistochemical Analysis as a Tool for the Diagnosis, Prognostic Evaluation and Treatment of Prostate Cancer: A Systematic Review of the Literature

in Cancer Molecular Targets and Therapeutics

Arie Carneiro
Álan Roger Gomes Barbosa
Lucas Seiti Takemura
Paulo Priante Kayano
Natasha Kouvaleski Saviano Moran
Carolina Ko Chen
Marcelo Langer Wroclawski
Gustavo Caserta Lemos
Isabela Werneck da Cunha
Marcos Takeo Obara

Frontiers in Oncology

doi 10.3389/fonc.2018.00377

21,133 views
24 citations

Original Research

Published on 03 Jun 2022

Fibroblast-Induced Paradoxical PI3K Pathway Activation in PTEN-Competent Colorectal Cancer: Implications for Therapeutic PI3K/mTOR Inhibition

in Molecular and Cellular Oncology

Fabiana Conciatori
Erica Salvati
Ludovica Ciuffreda
Senji Shirasawa
Italia Falcone
Francesco Cognetti
Gianluigi Ferretti
Massimo Zeuli
Donatella Del Bufalo
Chiara Bazzichetto

Frontiers in Oncology

doi 10.3389/fonc.2022.862806

3,713 views
6 citations

Original Research

Published on 23 Sep 2022

PTEN is recognized as a prognostic-related biomarker and inhibits proliferation and invasiveness of skull base chordoma cells

in Neurosurgery

Kaibing Tian
Junpeng Ma
Ke Wang
Da Li
Junting Zhang
Liang Wang
Zhen Wu

Frontiers in Surgery

doi 10.3389/fsurg.2022.1011845

3,058 views
3 citations

Original Research

Published on 30 Apr 2021

The Absence of PTEN in Breast Cancer Is a Driver of MLN4924 Resistance

in Cell Growth and Division

Meng-ge Du
Zhi-qiang Peng
Wen-bin Gai
Fan Liu
Wei Liu
Yu-jiao Chen
Hong-chang Li
Xin Zhang
Cui Hua Liu
Ling-qiang Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.667435

7,647 views
23 citations

Articles

Icariin Attenuates Amyloid-β (Aβ)-Induced Neuronal Insulin Resistance Through PTEN Downregulation

Post-Translational Modification of PTEN Protein: Quantity and Activity

Simultaneous Knockdown of Sprouty2 and PTEN Promotes Axon Elongation of Adult Sensory Neurons

Phosphatase and Tensin Homolog in Non-neoplastic Digestive Disease: More Than Just Tumor Suppressor

Case Report: Duodenal Carcinoma in a 40-Year-Old Asian Man With Cowden Syndrome

Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells

PTEN: Multiple Functions in Human Malignant Tumors

Activation of Type 4 Metabotropic Glutamate Receptor Regulates Proliferation and Neuronal Differentiation in a Cultured Rat Retinal Progenitor Cell Through the Suppression of the cAMP/PTEN/AKT Pathway

iNOS Associates With Poor Survival in Melanoma: A Role for Nitric Oxide in the PI3K-AKT Pathway Stimulation and PTEN S-Nitrosylation

Mechanism of action of decitabine in treating acute lymphoblastic leukemia

The Role of Immunohistochemical Analysis as a Tool for the Diagnosis, Prognostic Evaluation and Treatment of Prostate Cancer: A Systematic Review of the Literature

Fibroblast-Induced Paradoxical PI3K Pathway Activation in PTEN-Competent Colorectal Cancer: Implications for Therapeutic PI3K/mTOR Inhibition

PTEN is recognized as a prognostic-related biomarker and inhibits proliferation and invasiveness of skull base chordoma cells

The Absence of PTEN in Breast Cancer Is a Driver of MLN4924 Resistance