Pycnogenol | List of Frontiers open access articles

Review

Published on 02 May 2024

Pycnogenol® French maritime pine bark extract in randomized, double-blind, placebo-controlled human clinical studies

in Nutrition and Metabolism

Franziska Weichmann
Peter Rohdewald

Frontiers in Nutrition

doi 10.3389/fnut.2024.1389374

68,604 views
21 citations

Review

Published on 03 Jul 2019

Assessing the Efficacy and Mechanisms of Pycnogenol® on Cognitive Aging From In Vitro Animal and Human Studies

in Ethnopharmacology

Tamara Simpson
Christina Kure
Con Stough

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00694

65,467 views
28 citations

Review

Published on 02 May 2024

Review of the pharmacokinetics of French maritime pine bark extract (Pycnogenol®) in humans

in Nutrition and Metabolism

Jasmin Bayer
Petra Högger

Frontiers in Nutrition

doi 10.3389/fnut.2024.1389422

13,363 views
14 citations

Original Research

Published on 26 Jun 2024

Integrating network pharmacology and experimental verification to reveal the anti-inflammatory ingredients and molecular mechanism of pycnogenol

in Ethnopharmacology

Hongyu Liu
Jie Shi
Fei Liu
Litao Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1408304

4,631 views
5 citations

Review

Published on 11 Jun 2025

Neurodevelopmental disorders and gut-brain interactions: exploring the therapeutic potential of pycnogenol through microbial-metabolic-neural networks

in Intestinal Microbiome

Ling Chen
Zhiqiang Li
Yuying Fan

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1601888

6,815 views
5 citations

Review

Accepted on 20 Feb 2026

Therapeutic potential of pycnogenol: Antioxidant, anti-inflammatory, immunomodulatory, antiviral, and anticancer effects

in Pharmacology of Infectious Diseases

Mohammad Enamul Hoque Kayesh
Michinori Kohara
Kyoko Tsukiyama-Kohara

Frontiers in Pharmacology

Original Research

Published on 17 Nov 2025

Comparative efficacy and safety of botanical drugs for mild cognitive impairment: a systematic review and network meta-analysis

in Ethnopharmacology

Yifan Yang
Haixia Wang
Jianmeng Lü
Hui Zhang
Tao Wang
Yongmei Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657169

2,483 views
1 citation

Systematic Review

Published on 04 Oct 2023

Efficacy of L-arginine and Pycnogenol ® in the treatment of male erectile dysfunction: a systematic review and meta-analysis

in Reproduction

Yuting Tian
Qian Zhou
Wen Li
Meixi Liu
Qing Li
Qiu Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2023.1211720

51,100 views
5 citations

Articles

Pycnogenol® French maritime pine bark extract in randomized, double-blind, placebo-controlled human clinical studies

Assessing the Efficacy and Mechanisms of Pycnogenol® on Cognitive Aging From In Vitro Animal and Human Studies

Review of the pharmacokinetics of French maritime pine bark extract (Pycnogenol®) in humans

Integrating network pharmacology and experimental verification to reveal the anti-inflammatory ingredients and molecular mechanism of pycnogenol

Neurodevelopmental disorders and gut-brain interactions: exploring the therapeutic potential of pycnogenol through microbial-metabolic-neural networks

Therapeutic potential of pycnogenol: Antioxidant, anti-inflammatory, immunomodulatory, antiviral, and anticancer effects

Comparative efficacy and safety of botanical drugs for mild cognitive impairment: a systematic review and network meta-analysis

Efficacy of L-arginine and Pycnogenol ® in the treatment of male erectile dysfunction: a systematic review and meta-analysis