Pyroglutamate | List of Frontiers open access articles

Original Research

Published on 01 Mar 2018

The Bacteroidetes Q-Rule: Pyroglutamate in Signal Peptidase I Substrates

in Evolutionary and Genomic Microbiology

Matthias Bochtler
Danuta Mizgalska
Florian Veillard
Magdalena L. Nowak
John Houston
Paul Veith
Eric C. Reynolds
Jan Potempa

Frontiers in Microbiology

doi 10.3389/fmicb.2018.00230

7,225 views
25 citations

Mini Review

Published on 20 Aug 2021

N-Truncated Aβ Starting at Position Four—Biochemical Features, Preclinical Models, and Potential as Drug Target in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Thomas A. Bayer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.710579

5,541 views
16 citations

Review

Published on 03 Aug 2023

Development and evolution of human glutaminyl cyclase inhibitors (QCIs): an alternative promising approach for disease-modifying treatment of Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Daoyuan Chen
Qingxiu Chen
Xiaofei Qin
Peipei Tong
Liping Peng
Tao Zhang
Chunli Xia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1209863

5,692 views
6 citations

Original Research

Published on 23 Sep 2022

Targeting the innate repair receptor axis via erythropoietin or pyroglutamate helix B surface peptide attenuates hemolytic-uremic syndrome in mice

in Inflammation

Sophie Dennhardt
Wiebke Pirschel
Bianka Wissuwa
Diana Imhof
Christoph Daniel
Jan T. Kielstein
Isabel Hennig-Pauka
Kerstin Amann
Florian Gunzer
Sina M. Coldewey

Frontiers in Immunology

doi 10.3389/fimmu.2022.1010882

4,912 views
4 citations

Review

Published on 15 Feb 2024

Structural–functional diversity of CD47 proteoforms

in Cancer Immunity and Immunotherapy

Ting Zhang
Feng Wang
Lu Xu
Yong-Guang Yang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1329562

13,113 views
15 citations

Mini Review

Accepted on 17 Feb 2026

Immunomodulatory functions of glutaminyl cyclases QPCTL and QPCT

in Cancer Immunity and Immunotherapy

Hannah Elaine Smid
Jana Colotti
Sophia Nölp
Nike Sophia Arlt
Sophie Weber
Amelie Gumann
Stephan von Horsten
Axel Karow
Wolfgang Schuh

Frontiers in Immunology

Original Research

Published on 01 Nov 2019

Insight Into Mosquito GnRH-Related Neuropeptide Receptor Specificity Revealed Through Analysis of Naturally Occurring and Synthetic Analogs of This Neuropeptide Family

in Neuroendocrine Science

Azizia Wahedi
Gerd Gäde
Jean-Paul Paluzzi

Frontiers in Endocrinology

doi 10.3389/fendo.2019.00742

4,514 views
17 citations

Original Research

Published on 26 Jan 2026

Phyllosphere of senescent crops as a microbial N2O source

in Terrestrial Microbiology

Kanako Tago
Shin-Ichi Tokuda
Yuya Sato
Yasuyo Sekiyama
Yong Guo
Yong Wang
Yasuhiro Date
Shintaro Hara
Megumi Kuroiwa
Tsubasa Ohbayashi

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1650612

1,400 views

Brief Research Report

Published on 29 Jul 2021

N-Terminally Truncated and Pyroglutamate-Modified Aβ Forms Are Measurable in Human Cerebrospinal Fluid and Are Potential Markers of Disease Progression in Alzheimer’s Disease

in Neurodegeneration

Guido Domingo
Luisa Benussi
Claudia Saraceno
Michela Bertuzzi
Roland Nicsanu
Antonio Longobardi
Sonia Bellini
Alfredo Cagnotto
Mario Salmona
Giuliano Binetti

Frontiers in Neuroscience

doi 10.3389/fnins.2021.708119

6,054 views
18 citations

Original Research

Published on 08 Mar 2018

Synergistic Effect on Neurodegeneration by N-Truncated Aβ4−42 and Pyroglutamate Aβ3−42 in a Mouse Model of Alzheimer's Disease

in Alzheimer's Disease and Related Dementias

Jose S. Lopez-Noguerola
Nicolai M. E. Giessen
Maximilian Ueberück
Julius N. Meißner
Charlotte E. Pelgrim
Johnathan Adams
Oliver Wirths
Yvonne Bouter
Thomas A. Bayer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00064

4,486 views
12 citations

Original Research

Published on 13 Aug 2021

Postmortem Neocortical 3H-PiB Binding and Levels of Unmodified and Pyroglutamate Aβ in Down Syndrome and Sporadic Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Violetta N. Pivtoraiko
Tamara Racic
Eric E. Abrahamson
Victor L. Villemagne
Benjamin L. Handen
Ira T. Lott
Elizabeth Head
Milos D. Ikonomovic

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.728739

4,425 views
4 citations

Articles

The Bacteroidetes Q-Rule: Pyroglutamate in Signal Peptidase I Substrates

N-Truncated Aβ Starting at Position Four—Biochemical Features, Preclinical Models, and Potential as Drug Target in Alzheimer’s Disease

Development and evolution of human glutaminyl cyclase inhibitors (QCIs): an alternative promising approach for disease-modifying treatment of Alzheimer's disease

Targeting the innate repair receptor axis via erythropoietin or pyroglutamate helix B surface peptide attenuates hemolytic-uremic syndrome in mice

Structural–functional diversity of CD47 proteoforms

Immunomodulatory functions of glutaminyl cyclases QPCTL and QPCT

Insight Into Mosquito GnRH-Related Neuropeptide Receptor Specificity Revealed Through Analysis of Naturally Occurring and Synthetic Analogs of This Neuropeptide Family

Phyllosphere of senescent crops as a microbial N2O source

N-Terminally Truncated and Pyroglutamate-Modified Aβ Forms Are Measurable in Human Cerebrospinal Fluid and Are Potential Markers of Disease Progression in Alzheimer’s Disease

Synergistic Effect on Neurodegeneration by N-Truncated Aβ4−42 and Pyroglutamate Aβ3−42 in a Mouse Model of Alzheimer's Disease

Postmortem Neocortical 3H-PiB Binding and Levels of Unmodified and Pyroglutamate Aβ in Down Syndrome and Sporadic Alzheimer’s Disease