Randomized Experiments | List of Frontiers open access articles

Original Research

Published on 27 Feb 2026

Development of a novel duplex crystal digital PCR for the detection of PRRSV–1 and PRRSV–2

in Veterinary and Zoonotic Infection

Yuwen Shi
Jiakang He
Kaichuang Shi
Yanwen Yin
Feng Long
Shuping Feng
Zuzhang Wei

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1701517

149 views

Original Research

Published on 27 Feb 2026

Microbial community patterns in two geochemically contrasting zones within the alkaline lake Bagno dell'Acqua (Pantelleria Island, Italy)

in Extreme Microbiology

Agnese Piacentini
Stefano Amalfitano
Barbara Casentini
Andrea Butturini
Ilaria Mazzini
Marco Seminara
Emanuele Colica
Francesco Giuseppe Falese
Francesco Latino Chiocci
Cristina Mazzoni

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1773453

108 views

Case Report

Published on 27 Feb 2026

Penile involvement associated with renal pelvic squamous cell carcinoma: a case report and mechanistic considerations

in Genitourinary Oncology

Kotaro Masaki
Takuya Tsujino
Hiroyuki Okada
Yuki Yoshikawa
Ryoichi Maenosono
Yusaku Imura
Masashi Sanada
Kensuke Hirosuna
Yuta Furusawa
Rei Yoshimi

Frontiers in Oncology

doi 10.3389/fonc.2026.1761194

Review

Published on 27 Feb 2026

Tumor-infiltrating lymphocyte therapy in triple-negative breast cancer: from mechanistic exploration to clinical translation

in T Cell Biology

Yongxi Wang
Zhe Zhang
Zhuo Chen
Xiaoyun Xie
Fang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1741333

130 views

Review

Published on 27 Feb 2026

Ferroptosis reshapes the tumor immune microenvironment: molecular mechanisms, immune regulation, and therapeutic synergistic strategies

in Cancer Immunity and Immunotherapy

Zhuangwei Lv
Zixian Liu
Ziru Nie
Ning Li
Lingbei Kong
Fangfang Shen
Junna Jiao
Hui Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1772259

Review

Published on 27 Feb 2026

From passive monitoring to active engagement: a systematic review and meta-analysis of digital health technologies for improving objective physical activity and cardiorespiratory fitness in patients with obstructive sleep apnea

in Digital Public Health

Jingkang Xia
Jiayi Yao
Haozhe Wang
Yongliang Zhu
Lihong Mao
Xueqiang Zhu

Frontiers in Public Health

doi 10.3389/fpubh.2026.1760571

119 views

Review

Published on 27 Feb 2026

Epigenetic and mitoepigenetic regulation in cancer and therapeutic perspectives

in Pharmacology of Anti-Cancer Drugs

Selcen Celik-Uzuner
Ihsan Nalkiran
Ugur Uzuner
Hatice Sevim Nalkiran

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1760013

140 views

Original Research

Published on 27 Feb 2026

Predicting the acute pancreatitis severity with multi-machine learning models: constructing an online prediction platform

in Clinical and Diagnostic Microbiology and Immunology

Jie Cao
Shike Long
Huan Liu
Ribin Liao
Fu,an Chen
Xiyou Li
Lifeng Xu
Ying Liu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1760036

Editorial

Published on 27 Feb 2026

Editorial: Prevention and treatment of urolithiasis: innovation and novel techniques

in Genitourinary Surgery and Interventions

Steffi Kar Kei Yuen
Bo Xiao
Bhaskar Somani

Frontiers in Surgery

doi 10.3389/fsurg.2026.1785032

Original Research

Published on 27 Feb 2026

Automated manufacturing of clinical-grade BDCA2 CAR NK cells in a closed system for the treatment of blastic plasmacytoid dendritic cell neoplasm

in NK and Innate Lymphoid Cell Biology

Rita Pfeifer
Sabine Müller
Marcus Nitsche
Melanie Sohmen
Julia Kostyra
Arthur Bister
Cathrin Bleilevens
Janina Brauner
Angela Mekes
Juliane Raasch

Frontiers in Immunology

doi 10.3389/fimmu.2026.1761397

115 views

Review

Published on 27 Feb 2026

Marine environmental epigenetics: mechanisms, stress responses and applications to biomonitoring

in Marine Biology

Ana Francisca dos Santos David
Ana Julia Gaspar Schmitz
João Pedro Garrote
Maria Luiza Souza Vitor
Lorenzo Fontanive Bueno
Marcos Edgar Herkenhoff

Frontiers in Marine Science

doi 10.3389/fmars.2026.1771101

164 views

Review

Published on 27 Feb 2026

Heme oxygenase-1 and malaria pathogenesis

in Parasite Immunology

Theophilus Wakai
Shalom Chinedu
Israel Afolabi

Frontiers in Immunology

doi 10.3389/fimmu.2026.1777520

289 views

Review

Published on 27 Feb 2026

HMGB1: a key molecule linking chronic inflammation to complications in type 2 diabetes mellitus and a target for exercise intervention

in Diabetes: Molecular Mechanisms

Fu Pengyu
Xu Huiyun
Gong Lijing

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1769497

Brief Research Report

Published on 27 Feb 2026

Subcellular localization of enzymes involved in the biosynthesis of digoxin in Digitalis lanata

in Plant Pathogen Interactions

Viviane Zeng
Emily Carroll
Devon Burnside
Zhen Q. Wang

Frontiers in Plant Science

doi 10.3389/fpls.2026.1703671

220 views

Original Research

Published on 27 Feb 2026

Dasatinib and quercetin mitigate radiation-induced lung injury by eliminating senescent cells in a rat model

in Experimental Pharmacology and Drug Discovery

Jing Liu
Xue Ren
Hengjiao Wang
Defu Yang
Ying Yan
Ying Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1748788

251 views

Perspective

Published on 27 Feb 2026

Cardiac vagal decoupling: a conceptual basis for reflex-independent hemodynamic management under general anesthesia

in Perioperative Medicine

Shotaro Nagahama

Frontiers in Anesthesiology

doi 10.3389/fanes.2026.1756498

441 views

Articles

Development of a novel duplex crystal digital PCR for the detection of PRRSV–1 and PRRSV–2

Microbial community patterns in two geochemically contrasting zones within the alkaline lake Bagno dell'Acqua (Pantelleria Island, Italy)

Penile involvement associated with renal pelvic squamous cell carcinoma: a case report and mechanistic considerations

Tumor-infiltrating lymphocyte therapy in triple-negative breast cancer: from mechanistic exploration to clinical translation

Ferroptosis reshapes the tumor immune microenvironment: molecular mechanisms, immune regulation, and therapeutic synergistic strategies

From passive monitoring to active engagement: a systematic review and meta-analysis of digital health technologies for improving objective physical activity and cardiorespiratory fitness in patients with obstructive sleep apnea

Epigenetic and mitoepigenetic regulation in cancer and therapeutic perspectives

Predicting the acute pancreatitis severity with multi-machine learning models: constructing an online prediction platform

Editorial: Prevention and treatment of urolithiasis: innovation and novel techniques

Automated manufacturing of clinical-grade BDCA2 CAR NK cells in a closed system for the treatment of blastic plasmacytoid dendritic cell neoplasm

Marine environmental epigenetics: mechanisms, stress responses and applications to biomonitoring

Heme oxygenase-1 and malaria pathogenesis

HMGB1: a key molecule linking chronic inflammation to complications in type 2 diabetes mellitus and a target for exercise intervention

Subcellular localization of enzymes involved in the biosynthesis of digoxin in Digitalis lanata

Dasatinib and quercetin mitigate radiation-induced lung injury by eliminating senescent cells in a rat model

Cardiac vagal decoupling: a conceptual basis for reflex-independent hemodynamic management under general anesthesia