Research Problems | List of Frontiers open access articles

Review

Published on 04 Mar 2026

The role of immune regulation in peripheral nerve regeneration: functions of inflammatory cells and cytokines

in Inflammation Pharmacology

Yongkun Zhang
Haochun Zhang
Yun Su
Min Nuo
Wenguang Wu
Haochen Jiang
Xiangjun Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1735833

186 views

Original Research

Published on 04 Mar 2026

The effect of an early ambulation program based on cognitive behavioral therapy for elderly patients with kinesiophobia after total hip arthroplasty

in Geriatric Medicine

Yu Xie
Shuying Liu
Chunmei Li
Yan Luo
Ran Chen
Wanfei Wu
Lianyang Zhang
Qingshan Guo
Yufeng Zhao
Siru Zhou

Frontiers in Medicine

doi 10.3389/fmed.2026.1741605

Original Research

Published on 04 Mar 2026

Motivational profiles regarding biology amongst German upper secondary students and associations with perceived basic need satisfaction and pressure

in Educational Psychology

Lisa-Maria Kamps
Axel Grund
Matthias Wilde
Nadine Großmann

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1588742

102 views

Original Research

Published on 04 Mar 2026

Dual-level weighted cross-entropy loss function and multi-object region segmentation network evaluation for dynamic knee joint X-ray radiography based on a novel scoring criterion

in Medical Imaging and Nuclear Medicine

Shiming Wang
Tianqi Wu
Weiqing Huang
Jinglong Du
Ziran Chen
Zhibo Xiao
Qi Gao
Yun Liu
Yingying Chen
Peng Guo

Frontiers in Medicine

doi 10.3389/fmed.2026.1768134

Brief Research Report

Published on 04 Mar 2026

Cabozantinib versus placebo in patients with radioiodine-refractory differentiated thyroid cancer after prior vascular endothelial growth factor receptor-targeted therapy (COSMIC-311): outcomes by BRAF status

in Head and Neck Cancer

Marcia S. Brose
Bhumsuk Keam
Jolanta Krajewska
Ana O. Hoff
Fernanda Vaisman
Chia-Chi Lin
Erika Hitre
Daniel W. Bowles
Bruce Robinson
Steven I. Sherman

Frontiers in Oncology

doi 10.3389/fonc.2026.1748566

260 views

Original Research

Published on 04 Mar 2026

Morphological changes and lateralization of the thalamic nuclei in children with growth hormone deficiency

in Pediatric Endocrinology

Joo Young Lee
Sung-min Lim
Jung Hwan Oh
Hyuna Kim
Gang Yi Lee
Bong Gun Lee
Jeong-Kyu Hoh
Seung Yang
Hyun Ju Lee

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1678738

168 views

Original Research

Published on 04 Mar 2026

Beyond body mass index: visceral adiposity and metabolic alterations as early markers of atrial dysfunction and atrial fibrillation in midlife

in Obesity

Angelina Borizanova
Elena Kinova
Natalia Spasova
Assen Goudev

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1775534

Original Research

Published on 04 Mar 2026

Variation of the steroid profile in relation to training in women and its importance for anti-doping testing

in Exercise Physiology

A. Andersson
L. Ekström
O. Salamin
R. Nicoli
A. L. Hirschberg
E. Eklund

Frontiers in Physiology

doi 10.3389/fphys.2026.1733515

Original Research

Published on 04 Mar 2026

Comparison and excitation optimization of commercial quartz tuning forks for QEPAS

in Optics and Photonics

Lei Peng
Yihua Qian
Yaohong Zhao
Qing Wang
Yifeng Zhao
Qiang Fu

Frontiers in Physics

doi 10.3389/fphy.2026.1791440

Original Research

Published on 04 Mar 2026

Astragalus small molecules protect BMSCs from radiation-induced bystander effect and enhance lung cancer radiosensitivity via the primary cilium/TGF-βR1/Smad3 pathway

in Cancer Molecular Targets and Therapeutics

Zhiming Miao
Mengyuan Wu
Sichao Dai
Xin Wang
Yang Yang Li
Fuxian Liu
Zhiwei Liu
Liying Zhang
Yongqi Liu

Frontiers in Oncology

doi 10.3389/fonc.2026.1732029

171 views

Original Research

Published on 04 Mar 2026

Efficacy of local convection enhanced delivery of chemotherapy using an intracerebral osmotic pump in a rat model of glioblastoma

in Neuro-Oncology and Neurosurgical Oncology

John McDaid
Julian E. Bailes
Neilank K. Jha
George Bobustuc
Reed Berlet
Cassidy Kessinger
Eliana Whitcomb
John M. Lee
Daniil P. Aksenov
Matthew Walker

Frontiers in Oncology

doi 10.3389/fonc.2026.1775053

Original Research

Published on 04 Mar 2026

Effects of weighted vests versus elastic bands plyometric jump training on lower-body physical performance adaptations in volleyball players

in Exercise Physiology

Yichen Bao
Yuankai Qiao
Shuowen Yang

Frontiers in Physiology

doi 10.3389/fphys.2026.1756391

Review

Published on 04 Mar 2026

Advances in targeting myocardial fibrosis: integrating mechanisms and therapeutics

in Heart Failure and Transplantation

Zihui Xu
Yuyan Zhao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1769016

Original Research

Published on 04 Mar 2026

Unveiling biomarkers of telitacicept’s efficacy in SLE treatment through proteomics and metabolomics

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Huiyu Nie
Siyuan Chang
Hanhan Chen
Jiahui Shi
Shu Li
Xiaofei Peng
Wei Cheng
Jia Wang
Qi Tang
Yan Ge

Frontiers in Immunology

doi 10.3389/fimmu.2026.1779880

Original Research

Published on 04 Mar 2026

Restoring sediment continuity in large regulated rivers: a 2D-informed 1D morphodynamic framework applied to the Hungarian Danube

in Freshwater Science

Sándor Baranya

Frontiers in Environmental Science

doi 10.3389/fenvs.2026.1762248

103 views

Review

Published on 04 Mar 2026

Insights from the high-altitude animal gut adaptation model: mechanisms of obesity regulation via microbiota-derived metabolite homeostasis and the gut-X axis

in Microbial Symbioses

Lijuan Cao
Wanlong Zhu

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1795452

Articles

The role of immune regulation in peripheral nerve regeneration: functions of inflammatory cells and cytokines

The effect of an early ambulation program based on cognitive behavioral therapy for elderly patients with kinesiophobia after total hip arthroplasty

Motivational profiles regarding biology amongst German upper secondary students and associations with perceived basic need satisfaction and pressure

Dual-level weighted cross-entropy loss function and multi-object region segmentation network evaluation for dynamic knee joint X-ray radiography based on a novel scoring criterion

Cabozantinib versus placebo in patients with radioiodine-refractory differentiated thyroid cancer after prior vascular endothelial growth factor receptor-targeted therapy (COSMIC-311): outcomes by BRAF status

Morphological changes and lateralization of the thalamic nuclei in children with growth hormone deficiency

Beyond body mass index: visceral adiposity and metabolic alterations as early markers of atrial dysfunction and atrial fibrillation in midlife

Variation of the steroid profile in relation to training in women and its importance for anti-doping testing

Comparison and excitation optimization of commercial quartz tuning forks for QEPAS

Astragalus small molecules protect BMSCs from radiation-induced bystander effect and enhance lung cancer radiosensitivity via the primary cilium/TGF-βR1/Smad3 pathway

Efficacy of local convection enhanced delivery of chemotherapy using an intracerebral osmotic pump in a rat model of glioblastoma

Effects of weighted vests versus elastic bands plyometric jump training on lower-body physical performance adaptations in volleyball players

Advances in targeting myocardial fibrosis: integrating mechanisms and therapeutics

Unveiling biomarkers of telitacicept’s efficacy in SLE treatment through proteomics and metabolomics

Restoring sediment continuity in large regulated rivers: a 2D-informed 1D morphodynamic framework applied to the Hungarian Danube

Insights from the high-altitude animal gut adaptation model: mechanisms of obesity regulation via microbiota-derived metabolite homeostasis and the gut-X axis