Retigabine | List of Frontiers open access articles

Original Research

Published on 27 Feb 2023

Kv7-specific activators hyperpolarize resting membrane potential and modulate human iPSC-derived sensory neuron excitability

in Pharmacology of Ion Channels and Channelopathies

Mark Estacion
Shujun Liu
Xiaoyang Cheng
Sulayman Dib-Hajj
Stephen G. Waxman

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1138556

6,302 views
7 citations

Original Research

Published on 15 Dec 2020

The Functional Availability of Arterial Kv7 Channels Is Suppressed Considerably by Large-Conductance Calcium-Activated Potassium Channels in 2- to 3-Month Old but Not in 10- to 15-Day Old Rats

in Membrane Physiology and Membrane Biophysics

Dongyu Ma
Dina Gaynullina
Nadine Schmidt
Mitko Mladenov
Rudolf Schubert

Frontiers in Physiology

doi 10.3389/fphys.2020.597395

4,417 views
17 citations

Original Research

Published on 14 Oct 2022

Excitatory and inhibitory hippocampal neurons differ in their homeostatic adaptation to chronic M-channel modulation

in Molecular Signalling and Pathways

Lior Bar
Lia Shalom
Jonathan Lezmy
Asher Peretz
Bernard Attali

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.972023

4,759 views
8 citations

Original Research

Published on 04 Jun 2021

Oxaliplatin Depolarizes the IB4– Dorsal Root Ganglion Neurons to Drive the Development of Neuropathic Pain Through TRPM8 in Mice

in Pain Mechanisms and Modulators

Bin Wu
Xiaolin Su
Wentong Zhang
Yi-Hong Zhang
Xinghua Feng
Yong-Hua Ji
Zhi-Yong Tan

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.690858

7,971 views
26 citations

Original Research

Published on 23 Dec 2021

The Changes of KCNQ5 Expression and Potassium Microenvironment in the Retina of Myopic Guinea Pigs

in Integrative Physiology

Qin Yang
Qing Qing Tan
Chang Jun Lan
Bo Zhen Lv
Gui Mei Zhou
Wei Qi Zhong
Zhi Ming Gu
Yu Mei Mao
Xuan Liao

Frontiers in Physiology

doi 10.3389/fphys.2021.790580

3,775 views
11 citations

Original Research

Published on 03 Mar 2022

Molecular Insights Into Binding and Activation of the Human KCNQ2 Channel by Retigabine

in Biological Modeling and Simulation

Barbara Garofalo
Alexandre M.J.J. Bonvin
Andrea Bosin
Francesco P. Di Giorgio
Rosella Ombrato
Attilio V. Vargiu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.839249

6,467 views
5 citations

Original Research

Published on 30 Jun 2020

Inhibition of M/Kv7 Currents Contributes to Chloroquine-Induced Itch in Mice

in Pain Mechanisms and Modulators

Dong Zhang
Hongchao Men
Ludi Zhang
Xiangxin Gao
Jingjing Wang
Leying Li
Qiaoying Zhu
Hailin Zhang
Zhanfeng Jia

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2020.00105

5,709 views
6 citations

Original Research

Published on 29 Nov 2016

M-currents (Kv7.2-7.3/KCNQ2-KCNQ3) Are Responsible for Dysfunctional Autonomic Control in Hypertensive Rats

in Autonomic Neuroscience

Torill Berg

Frontiers in Physiology

doi 10.3389/fphys.2016.00584

4,096 views
17 citations

Original Research

Published on 13 Apr 2021

KCNQ Current Contributes to Inspiratory Burst Termination in the Pre-Bötzinger Complex of Neonatal Rats in vitro

in Respiratory Physiology and Pathophysiology

Ann L. Revill
Alexis Katzell
Christopher A. Del Negro
William K. Milsom
Gregory D. Funk

Frontiers in Physiology

doi 10.3389/fphys.2021.626470

4,247 views
14 citations

Original Research

Published on 20 Feb 2018

Kv7(KCNQ)-K+-Channels Influence Total Peripheral Resistance in Female but Not Male Rats, and Hamper Catecholamine Release in Hypertensive Rats of Both Sexes

in Autonomic Neuroscience

Torill Berg

Frontiers in Physiology

doi 10.3389/fphys.2018.00117

3,917 views
11 citations

Original Research

Published on 20 Mar 2024

Participation of calcium-permeable AMPA receptors in the regulation of epileptiform activity of hippocampal neurons

Valery Petrovich Zinchenko
Ilia Yu. Teplov
Artem Mikhailovich Kosenkov
Sergei Gennadievich Gaidin
Bakytzhan Kairatuly Kairat
Sultan Tuleukhanovich Tuleukhanov

Frontiers in Synaptic Neuroscience

doi 10.3389/fnsyn.2024.1349984

5,435 views
8 citations

Original Research

Published on 22 Apr 2025

Gaussian white noise stimulation as an alternative method to excite sensory neurons

in Pharmacology of Ion Channels and Channelopathies

Thomas Losgott
Klaus W. Schicker
Karlheinz Hilber
Stefan Boehm
Isabella Salzer

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561905

1,844 views

Review

Published on 13 Dec 2021

Peripheral Voltage-Gated Cation Channels in Neuropathic Pain and Their Potential as Therapeutic Targets

in Pain Mechanisms

Sascha R. A. Alles
Peter A. Smith

Frontiers in Pain Research

doi 10.3389/fpain.2021.750583

23,794 views
70 citations

Brief Research Report

Published on 25 May 2020

Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy in vivo

in Autonomic Neuroscience

Laiche Djouhri
Asad Zeidan
Seham A. Abd El-Aleem
Trevor Smith

Frontiers in Neuroscience

doi 10.3389/fnins.2020.00530

5,537 views
20 citations

Original Research

Published on 19 Jun 2020

Modulation of KV7 Channel Deactivation by PI(4,5)P2

in Pharmacology of Ion Channels and Channelopathies

Carlos A. Villalba-Galea

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00895

4,285 views
2 citations

Original Research

Published on 07 Oct 2013

Functional effects of KCNQ K+ channels in airway smooth muscle

in Respiratory Physiology and Pathophysiology

Alexey I Evseev
Iurii Semenov
Crystal Archer
Jorge Medina
Peter H Dube
Mark S Shapiro
Robert Brenner

Frontiers in Physiology

doi 10.3389/fphys.2013.00277

8,049 views
24 citations

Articles

Kv7-specific activators hyperpolarize resting membrane potential and modulate human iPSC-derived sensory neuron excitability

The Functional Availability of Arterial Kv7 Channels Is Suppressed Considerably by Large-Conductance Calcium-Activated Potassium Channels in 2- to 3-Month Old but Not in 10- to 15-Day Old Rats

Excitatory and inhibitory hippocampal neurons differ in their homeostatic adaptation to chronic M-channel modulation

Oxaliplatin Depolarizes the IB4– Dorsal Root Ganglion Neurons to Drive the Development of Neuropathic Pain Through TRPM8 in Mice

The Changes of KCNQ5 Expression and Potassium Microenvironment in the Retina of Myopic Guinea Pigs

Molecular Insights Into Binding and Activation of the Human KCNQ2 Channel by Retigabine

Inhibition of M/Kv7 Currents Contributes to Chloroquine-Induced Itch in Mice

M-currents (Kv7.2-7.3/KCNQ2-KCNQ3) Are Responsible for Dysfunctional Autonomic Control in Hypertensive Rats

KCNQ Current Contributes to Inspiratory Burst Termination in the Pre-Bötzinger Complex of Neonatal Rats in vitro

Kv7(KCNQ)-K+-Channels Influence Total Peripheral Resistance in Female but Not Male Rats, and Hamper Catecholamine Release in Hypertensive Rats of Both Sexes

Participation of calcium-permeable AMPA receptors in the regulation of epileptiform activity of hippocampal neurons

Gaussian white noise stimulation as an alternative method to excite sensory neurons

Peripheral Voltage-Gated Cation Channels in Neuropathic Pain and Their Potential as Therapeutic Targets

Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy in vivo

Modulation of KV7 Channel Deactivation by PI(4,5)P2

Functional effects of KCNQ K+ channels in airway smooth muscle