Rrl | List of Frontiers open access articles

Original Research

Published on 31 Jul 2025

Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7 through the AMPK-mTOR-NF-κB pathway

in Mucosal Immunity

Chunmei Ren
Kento Tazawa
Nobuyuki Kawashima
Risa Ohshima
Yamato Okada
Shihan Wang
Ziniu Yu
Peifeng Han
Yujin Ohsugi
Sayaka Katagiri

Frontiers in Immunology

doi 10.3389/fimmu.2025.1643676

198 views

Original Research

Published on 31 Jul 2025

B2SAPP: blockchain based solution for maritime security applications

in Computer Security

Aristeidis Farao
Apostolis Zarras
Anastassis Voudouris
Georgios Paparis
Christos Xenakis

Frontiers in Computer Science

doi 10.3389/fcomp.2025.1572009

252 views

Original Research

Published on 31 Jul 2025

PolyLLM: polypharmacy side effect prediction via LLM-based SMILES encodings

in Experimental Pharmacology and Drug Discovery

Sadra Hakim
Alioune Ngom

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1617142

241 views

Original Research

Published on 31 Jul 2025

Differentiable black-box and gray-box modeling of nonlinear audio effects

in Audio and Acoustic Signal Processing

Marco Comunità
Christian J. Steinmetz
Joshua D. Reiss

Frontiers in Signal Processing

doi 10.3389/frsip.2025.1580395

315 views

Clinical Trial

Published on 31 Jul 2025

Digital outdoor exercise program for obese patients with type 2 diabetes mellitus: a non-inferiority randomized controlled trial

in Clinical Diabetes

Jian Cui
Qiang Liu
Lihua Huang
Haoyan Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1654129

248 views

Original Research

Published on 31 Jul 2025

Previous COVID-19 infection significantly reduces elastase levels in newly diagnosed pulmonary tuberculosis patients

in Microbial Immunology

Nancy Hilda Joseph
Alangudi Palaniappan Natarajan
Saravanan Natarajan
Chinnaiyan Ponnuraja
Madeshwaran A
Gunaparvathy I
Hemalatha P
Rajeshwari S
Lavanya Jayabal
Mahilmaran Ayyamperumal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586789

174 views

Original Research

Published on 31 Jul 2025

α-Lipoic acid mitigates age-related macular degeneration via ferroptosis: integrative multi-omics and network pharmacology

in Neuropharmacology

Yaqiong Zhang
Yuanyuan Chen
Chenglin Sun
Fang Li
Yin Shen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1626907

179 views

Review

Published on 31 Jul 2025

Notch signaling in diabetic kidney disease: recent progress

in Diabetes: Molecular Mechanisms

Zhi-Hui Wang
Wei Tu
Ya-Ni Long
Peng-Fei Li
Kai-Ying He
Jing Wu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1537769

162 views

Original Research

Published on 31 Jul 2025

Organization and support as an essential part of group exercise programs for older people with dementia: an end-user interview study

in Physical Activity in the Prevention and Management of Disease

Kristin Taraldsen
Arnhild J. Nygård
Elisabeth Boulton
Guro Grønningsæter
Marit H. Erland
Nina Waldenstrøm
Linda Johnsen
Gro G. Tangen
Randi Granbo

Frontiers in Sports and Active Living

doi 10.3389/fspor.2025.1526163

126 views

Original Research

Published on 31 Jul 2025

Liproxstatin-1 improves boar sperm quality during in vitro liquid preservation at 17°C, associated with reduction of oxidative stress and ferroptosis markers

in Animal Reproduction - Theriogenology

Yang Li
Xue Liu
Ye Cheng
Jingchun Li
Yuling Zhou
Qing Guo

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1611661

148 views

Original Research

Published on 31 Jul 2025

Why have extensive efforts to improve adolescents’ physical fitness seen limited success? A mediation analysis of physical activity enjoyment, physical activity and physical fitness

in Sport Psychology

Jiale Peng
Wenlang Yu
Wenxing Wang
Leyi Wang
Wei Shan
Hong Ren

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1572826

136 views

Review

Published on 31 Jul 2025

A review on metallothionein research in marine and estuarine realms: past paradigms and future vistas

in Marine Pollution

Adnan H. Gora
M. P. Sreeram
Saima Rehman
Qurat Ul Ain
Kajal Chakraborty
D. Prema
R. Lavanya
Prabhugouda Siriyappagouder
P. S. Asha

Frontiers in Marine Science

doi 10.3389/fmars.2025.1636760

203 views

Original Research

Published on 31 Jul 2025

Checkpoint antibody receptor modified ARMed CAR T circumvents the suppressive immunome in GBM

in T Cell Biology

Danielle R. Cook
Alina C. Boesteanu
Yibo Yin
Reiss Reid
Laura Roccograndi
Nadia Dahmane
Maria Martinez-Lage
Donald M. O’Rourke
Carl H. June
Laura A. Johnson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579925

294 views

Brief Research Report

Published on 31 Jul 2025

The world needs less plastic: the role of psychological distance and self-efficacy in environmental messages

in Science and Environmental Communication

Kathryn E. Cooper
Laurel Brinkerhoff
Kristen D. Landreville

Frontiers in Communication

doi 10.3389/fcomm.2025.1579912

285 views

Original Research

Published on 31 Jul 2025

The interplay of prenatal stress and prenatal depression in Chinese couples: based on the actor-partner interdependence model

in Perinatal Psychiatry

Xiaoqing Liu
Yuting Dong
Jungu Zhou
Shiying Lin
Minghuan Liu
Hang Zeng
Xiaowan Zhou
Yang Song
Xiaoxu Xie
Qiuping Liao

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1607470

168 views

Correction

Published on 31 Jul 2025

Correction: Age- and sex-related development of osteosarcopenia in the aging Octodon degus rodent model

in Musculoskeletal Aging

Pablo Gallo-Soljancic
Maria Egle De Stefano
Ana-Maria Lucas-Ochoa
Consuelo Sánchez-Rodrigo
Lorena Cuenca-Bermejo
Ana-María González-Cuello
Emiliano Fernández-Villalba
Maria-Trinidad Herrero

Frontiers in Aging

doi 10.3389/fragi.2025.1669031

Articles

Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7 through the AMPK-mTOR-NF-κB pathway

B2SAPP: blockchain based solution for maritime security applications

PolyLLM: polypharmacy side effect prediction via LLM-based SMILES encodings

Differentiable black-box and gray-box modeling of nonlinear audio effects

Digital outdoor exercise program for obese patients with type 2 diabetes mellitus: a non-inferiority randomized controlled trial

Previous COVID-19 infection significantly reduces elastase levels in newly diagnosed pulmonary tuberculosis patients

α-Lipoic acid mitigates age-related macular degeneration via ferroptosis: integrative multi-omics and network pharmacology

Notch signaling in diabetic kidney disease: recent progress

Organization and support as an essential part of group exercise programs for older people with dementia: an end-user interview study

Liproxstatin-1 improves boar sperm quality during in vitro liquid preservation at 17°C, associated with reduction of oxidative stress and ferroptosis markers

Why have extensive efforts to improve adolescents’ physical fitness seen limited success? A mediation analysis of physical activity enjoyment, physical activity and physical fitness

A review on metallothionein research in marine and estuarine realms: past paradigms and future vistas

Checkpoint antibody receptor modified ARMed CAR T circumvents the suppressive immunome in GBM

The world needs less plastic: the role of psychological distance and self-efficacy in environmental messages

The interplay of prenatal stress and prenatal depression in Chinese couples: based on the actor-partner interdependence model

Correction: Age- and sex-related development of osteosarcopenia in the aging Octodon degus rodent model