Safety Switch | List of Frontiers open access articles

Original Research

Published on 11 Oct 2022

Safety switch optimization enhances antibody-mediated elimination of CAR T cells

in Molecular Medicine and Cancer Treatment

Tamer B. Shabaneh
Howell F. Moffett
Sylvia M. Stull
Thomas Derezes
Leah J. Tait
Spencer Park
Stan R. Riddell
Marc J. Lajoie

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2022.1026474

10,224 views
15 citations

Perspective

Published on 06 Nov 2014

Suicide genes: monitoring cells in patients with a safety switch

in Experimental Pharmacology and Drug Discovery

Linda G. Eissenberg
Michael Rettig
Farrokh Dehdashti
David Piwnica-Worms
John F. DiPersio

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00241

8,330 views
13 citations

Review

Published on 06 Aug 2019

Adoptive T Cell Therapy Following Haploidentical Hematopoietic Stem Cell Transplantation

in Alloimmunity and Transplantation

Ping Zhang
Siok-Keen Tey

Frontiers in Immunology

doi 10.3389/fimmu.2019.01854

9,700 views
12 citations

Review

Published on 30 Mar 2021

Engineered TCR-T Cell Immunotherapy in Anticancer Precision Medicine: Pros and Cons

in Cancer Immunity and Immunotherapy

Qijie Zhao
Yu Jiang
Shixin Xiang
Parham Jabbarzadeh Kaboli
Jing Shen
Yueshui Zhao
Xu Wu
Fukuan Du
Mingxing Li
Chi Hin Cho

Frontiers in Immunology

doi 10.3389/fimmu.2021.658753

51,272 views
139 citations

Original Research

Published on 14 Sep 2022

Combinatorial suicide gene strategies for the safety of cell therapies

in T Cell Biology

Corey Falcon
Lauren Smith
Mustafa Al-Obaidi
Mohammed Abu Zaanona
Katelyn Purvis
Kentaro Minagawa
Mohammad Athar
Donna Salzman
Ravi Bhatia
Frederick Goldman

Frontiers in Immunology

doi 10.3389/fimmu.2022.975233

7,461 views
11 citations

Original Research

Published on 19 Oct 2021

Inclusion of the Inducible Caspase 9 Suicide Gene in CAR Construct Increases Safety of CAR.CD19 T Cell Therapy in B-Cell Malignancies

in Cancer Immunity and Immunotherapy

Marika Guercio
Simona Manni
Iolanda Boffa
Simona Caruso
Stefano Di Cecca
Matilde Sinibaldi
Zeinab Abbaszadeh
Antonio Camera
Roselia Ciccone
Vinicia Assunta Polito

Frontiers in Immunology

doi 10.3389/fimmu.2021.755639

10,999 views
65 citations

Articles

Safety switch optimization enhances antibody-mediated elimination of CAR T cells

Suicide genes: monitoring cells in patients with a safety switch

Adoptive T Cell Therapy Following Haploidentical Hematopoietic Stem Cell Transplantation

Engineered TCR-T Cell Immunotherapy in Anticancer Precision Medicine: Pros and Cons

Combinatorial suicide gene strategies for the safety of cell therapies

Inclusion of the Inducible Caspase 9 Suicide Gene in CAR Construct Increases Safety of CAR.CD19 T Cell Therapy in B-Cell Malignancies