Severe Aplastic Anemia | List of Frontiers open access articles

Original Research

Published on 15 Mar 2022

Pre-Transplant Platelet Refractoriness and Alternative Donors Are Associated With Cytomegalovirus Retinitis in Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia

in Clinical and Diagnostic Microbiology and Immunology

Yuehong Zhang
Yuqin Liang
Xu Zhang
Shunqing Wang
Jinpeng Cao
Zongyin Gao
Ling Li
Wenjian Mo

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2022.870296

3,672 views
5 citations

Case Report

Published on 23 Sep 2024

Rapid diagnosis of Aspergillus flavus infection in acute very severe aplastic anemia with metagenomic next-generation sequencing: a case report and literature review

in Infectious Diseases: Pathogenesis and Therapy

Ying Kang
Xiaojing Zhang
Cao Qin
Yafeng Zheng
Wei Gai
Xiaofei Jia
Bo Shao
Shuai Zhang
Hao Jiang
XiaoJun Huang

Frontiers in Medicine

doi 10.3389/fmed.2024.1413964

2,754 views
4 citations

Original Research

Published on 23 Aug 2021

Plasma Metabolomic and Intestinal Microbial Analyses of Patients With Severe Aplastic Anemia

in Molecular and Cellular Pathology

Yuanyuan Shao
Weiwei Qi
Xiaomei Zhang
Ningyuan Ran
Chunyan Liu
Rong Fu
Zonghong Shao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.669887

5,145 views
15 citations

Clinical Trial

Published on 24 Jul 2024

Avatrombopag as alternative therapy for severe aplastic anemia patients who are intolerant or unresponsive to eltrombopag

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ting Zhang
Qingling Yu
Xiaoyu Chen
Hui Yang
Yuemin Gong
Yawen Zhang
Xiaoqing Liu
Zhinan Yang
Yu Fang
Xue Yan

Frontiers in Immunology

doi 10.3389/fimmu.2024.1393829

4,638 views

Original Research

Published on 16 Jun 2021

Upregulated Expression of Profilin1 on Dendritic Cells in Patients With Severe Aplastic Anemia

in Autoimmune and Autoinflammatory Disorders

Hong Yu
Yang Zhao
Xiaofeng Pan
Chunyan Liu
Rong Fu

Frontiers in Immunology

doi 10.3389/fimmu.2021.631954

4,162 views
9 citations

Case Report

Published on 12 Sep 2024

Very severe aplastic anemia in a child with pulmonary mucormycosis: a case report

in Pediatric Hematology and Hematological Malignancies

Minchun Huang
Nanchuan Jiang
Yahui Ren
Yun Peng
Xiaoyan Wu

Frontiers in Pediatrics

doi 10.3389/fped.2024.1453059

2,519 views
1 citation

Original Research

Published on 20 Apr 2023

Development and validation of early death risk score model for emergency status prediction in very severe aplastic anemia

in Alloimmunity and Transplantation

Xu Liu
Wenrui Yang
Li Zhang
Liping Jing
Lei Ye
Kang Zhou
Yuan Li
Jianping Li
Huihui Fan
Yang Yang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1175048

3,012 views
5 citations

Clinical Trial

Published on 26 May 2022

Predicting Response of Severe Aplastic Anemia to Rabbit-Antithymocyte Immunoglobulin Based Immunosuppressive Therapy Combined With Eltrombopag

in Autoimmune and Autoinflammatory Disorders

Ruixin Li
Jiongtao Zhou
Zhengyuan Liu
Xi Chen
Qiqiang Long
Yan Yang
Shengyun Lin
Jinsong Jia
Guangsheng He
JianYong Li

Frontiers in Immunology

doi 10.3389/fimmu.2022.884312

4,578 views
13 citations

Case Report

Published on 08 Aug 2022

Case report: Application of nirmatrelvir/ritonavir to treat COVID-19 in a severe aplastic anemia child after allogeneic hematopoietic stem cell transplantation

in Pediatric Infectious Diseases

Jinhua Huang
Di Yin
Xia Qin
Mei Yu
Beilei Jiang
Jing Chen
Qing Cao
Zhiguo Tang

Frontiers in Pediatrics

doi 10.3389/fped.2022.935118

4,447 views
9 citations

Brief Research Report

Published on 09 Jul 2025

Successful third haploidentical hematopoietic stem cell transplantation after two graft failures in a pediatric patient with severe aplastic anemia: a case report with five-year follow-up

in Alloimmunity and Transplantation

Xuewei Li
Wenhui Zhang
Saisai Li
Xiaolin Ma
Xue Shi
Wei Wang
Lingjie Sun
Kuan Qiu
Yanxia Zhao
Chunting Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607926

1,872 views

Case Report

Published on 05 Oct 2022

Case Report: Chronic hepatitis E in a hematopoietic stem cell transplant recipient: The first report of hepatitis E virus genotype 4 causing chronic infection in a non-solid organ recipient

in Microbial Immunology

Zihao Chen
Junfeng Wei
Li Jiang
Dong Ying
Weikun Tian
Mengyang Zhang
Guiping Wen
Siling Wang
Chang Liu
Yingbin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2022.954697

4,236 views
6 citations

Systematic Review

Published on 24 Apr 2023

The efficacy and the safety of eltrombopag in pediatric patients with severe aplastic anemia: a systematic review

in Pediatric Hematology and Hematological Malignancies

Maria Maddalena Marrapodi
Annamaria Mascolo
Domenico Roberti
Martina Di Martino
Concetta Rafaniello
Consiglia Riccardi
Francesca Rossi

Frontiers in Pediatrics

doi 10.3389/fped.2023.1149718

8,259 views
3 citations

Case Report

Published on 14 Apr 2025

Rhino-orbito-cerebral mucormycosis after allogeneic hematopoietic stem cell transplantation for very severe aplastic anemia in a child: a case report

in Pediatric Hematology and Hematological Malignancies

Yimei Ma
Ziting Xia
Bochao Cheng
Bo Wang
Xingming Huang
Xiaoxi Lu

Frontiers in Pediatrics

doi 10.3389/fped.2025.1529656

2,605 views
1 citation

Original Research

Published on 04 Jan 2022

Multi-Omics Profiling Identifies Pathways Associated With CD8+ T-Cell Activation in Severe Aplastic Anemia

in Epigenomics and Epigenetics

Xing You
Qiong Yang
Kai Yan
Song-Rong Wang
Rong-Rong Huang
Shun-Qing Wang
Cai-Yue Gao
Liang Li
Zhe-Xiong Lian

Frontiers in Genetics

doi 10.3389/fgene.2021.790990

7,555 views
16 citations

Original Research

Published on 16 Aug 2024

Comparison of hematopoietic stem cell transplantation and repeated intensified immunosuppressive therapy as second-line treatment for relapsed/refractory severe aplastic anemia

in Alloimmunity and Transplantation

Lining Zhang
Jianping Li
Weiru Liang
Xiaoyu Zhang
Shulian Chen
Yuanyuan Shi
Mengze Hao
Xiaoli Zhao
Ming Gong
Jialin Wei

Frontiers in Immunology

doi 10.3389/fimmu.2024.1425076

4,469 views
1 citation

Case Report

Published on 01 Oct 2025

Case report: Spontaneous remission of severe aplastic anemia mediated by mutant hematopoietic stem cells evading T-cell attack

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Kohei Shiroshita
Yoshitaka Zaimoku
Himari Kudo
Naoshi Obara
Kazuyoshi Hosomichi
Yui Kano
Miku Kobayashi
Eriko Morishita
Hiroyuki Takamatsu
Takaaki Toyama

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635943

557 views

Articles

Pre-Transplant Platelet Refractoriness and Alternative Donors Are Associated With Cytomegalovirus Retinitis in Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia

Rapid diagnosis of Aspergillus flavus infection in acute very severe aplastic anemia with metagenomic next-generation sequencing: a case report and literature review

Plasma Metabolomic and Intestinal Microbial Analyses of Patients With Severe Aplastic Anemia

Avatrombopag as alternative therapy for severe aplastic anemia patients who are intolerant or unresponsive to eltrombopag

Upregulated Expression of Profilin1 on Dendritic Cells in Patients With Severe Aplastic Anemia

Very severe aplastic anemia in a child with pulmonary mucormycosis: a case report

Development and validation of early death risk score model for emergency status prediction in very severe aplastic anemia

Predicting Response of Severe Aplastic Anemia to Rabbit-Antithymocyte Immunoglobulin Based Immunosuppressive Therapy Combined With Eltrombopag

Case report: Application of nirmatrelvir/ritonavir to treat COVID-19 in a severe aplastic anemia child after allogeneic hematopoietic stem cell transplantation

Successful third haploidentical hematopoietic stem cell transplantation after two graft failures in a pediatric patient with severe aplastic anemia: a case report with five-year follow-up

Case Report: Chronic hepatitis E in a hematopoietic stem cell transplant recipient: The first report of hepatitis E virus genotype 4 causing chronic infection in a non-solid organ recipient

The efficacy and the safety of eltrombopag in pediatric patients with severe aplastic anemia: a systematic review

Rhino-orbito-cerebral mucormycosis after allogeneic hematopoietic stem cell transplantation for very severe aplastic anemia in a child: a case report

Multi-Omics Profiling Identifies Pathways Associated With CD8+ T-Cell Activation in Severe Aplastic Anemia

Comparison of hematopoietic stem cell transplantation and repeated intensified immunosuppressive therapy as second-line treatment for relapsed/refractory severe aplastic anemia

Case report: Spontaneous remission of severe aplastic anemia mediated by mutant hematopoietic stem cells evading T-cell attack