Sirna Screening | List of Frontiers open access articles

Original Research

Published on 01 Oct 2025

Targeting the CCL28-STAT3-PLAC8 axis to suppress metastasis and remodel tumor microenvironment in colorectal cancer

in Cancer Immunity and Immunotherapy

Yao Yang
Qixin Jiang
Zhe Zhu
Shun Zhang
Tao Du
Shuzheng Song
Xiaohua Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610540

124 views

Original Research

Published on 01 Oct 2025

Elucidating the multiscale mechanisms and therapeutic targets of caffeic acid in gastric cancer: a synergy of computational and experimental approaches

in Molecular Diagnostics and Therapeutics

Hongrong Zhang
Yufan Li
Ya Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1663517

568 views

Perspective

Published on 01 Oct 2025

Environmental sustainability, an essential outcome for implementation scientists to improve health

in Implementation Science

Virginia Mckay
Emmanuel Tetteh
Nicholas Wong
C. Bradley Kramer
Jason Burnham

Frontiers in Health Services

doi 10.3389/frhs.2025.1664446

352 views

Original Research

Published on 01 Oct 2025

High-content stimulated Raman pathology imaging and transcriptomics reveal leukemia subtype-specific lipid metabolic heterogeneity

in Comparative Immunology

Xuelian Cheng
Jing Liu
Ming Chen
Haoyu Wang
Shuxu Dong
Yuan Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662281

645 views

Original Research

Published on 01 Oct 2025

Structural elucidation of Langat virus helicase unveils dual-target inhibition for broad-spectrum anti-flaviviruses strategy

in Molecular Viral Pathogenesis

Ruixue Li
Zhen Han
Xiao He
Rongrong Zhong
Chen Chen

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1664344

854 views

Review

Published on 01 Oct 2025

Gut microbiota in hypothyroidism: pathogenic mechanisms and opportunities for precision microbiome interventions

in Microorganisms in Vertebrate Digestive Systems

Tao Jiang
Xiuqing Yang
Baihui Wu
Runchao Tao
Rongbing Chen
Libo Jin
Da Sun
Huibin Weng

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1661211

494 views

Review

Published on 01 Oct 2025

Advances in drug delivery systems for the management of gout and hyperuricemia

in Inflammation Pharmacology

Zining Peng
Fanyu Meng
Qian Deng
Yuanbo Huang
Danning Mao
Yuan Long
Weitian Yan
Jiangyun Peng
Xingqiang Wang
Nian Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1660890

865 views

Systematic Review

Published on 01 Oct 2025

Risk factors for postherpetic neuralgia: a meta-analysis based on demographic, clinical features, and treatment characteristics

in Viral Immunology

Jing Wang
Rong Tao
Yinghai Jiang
Zhuoya Ma
Lingjie Xia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667364

261 views

Review

Published on 01 Oct 2025

Advances in WRKY regulation of immune responses in medicinal plants

in Plant Pathogen Interactions

Xinying Zhong
Nana Chen
Hongwei Li
Yaxuan Wang
Ziyi Guo
Guiyuan Shi
Xingkai Zhan
Lin Li

Frontiers in Plant Science

doi 10.3389/fpls.2025.1659732

443 views

Original Research

Published on 01 Oct 2025

Cost-effectiveness of HLX01 (Hanlikang®) vs. rituximab combined with CHOP in treatment-naive diffuse large B-Cell lymphoma: a partitioned survival model analysis

in Drugs Outcomes Research and Policies

Chang Wang
Yuanqing Huang
Langling Rao
Chunling Yu
Yingxin Zhang
Yingtao Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1498735

453 views

Clinical Trial

Published on 01 Oct 2025

Impact of using supplemented thylakoids derived from spinach for 12 weeks of high-intensity functional training on adipo-myokines in obese males

in Sport and Exercise Nutrition

Asieh Abbassi-Daloii
Maha Hoteit
Zahra Sadek
Mahboubeh Khak-Rand
Akbar Ramezani
Zhaleh Pashaei
Mahsa Afshar
Kurt A. Escobar
Rashmi Supriya
Ayoub Saeidi

Frontiers in Nutrition

doi 10.3389/fnut.2025.1513681

501 views

Conceptual Analysis

Published on 01 Oct 2025

From liberal paralysis to green republican resolution? Conceptualising, illustrating, and addressing problems of governability in eco-social politics

in Comparative Governance

Veith Selk
Niklas Klüh

Frontiers in Political Science

doi 10.3389/fpos.2025.1418880

260 views

Original Research

Published on 01 Oct 2025

Using drama in café dialogue as an alternative approach in multicultural educational processes

in Language, Culture and Diversity

Mette Bøe Lyngstad

Frontiers in Education

doi 10.3389/feduc.2025.1392678

401 views

Original Research

Published on 01 Oct 2025

The more you play, the better you feel: a dose–response analysis of pickleball and mental wellbeing in U.S. adults

in Sport Psychology

Oluwatoyosi B. A. Owoeye
Joseph Grese
Madeline Stenersen
Ted Yemm
Chris Sebelski
Katie Sniffen

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1676695

1,279 views

Original Research

Published on 01 Oct 2025

Conflict, cod and Calanus: can technology increase trust in management of a contested fishery?

in Marine Affairs and Policy

Katherine M. Crosman
Adam L. Hayes
Emlyn J. Davies
Sanna Majaneva

Frontiers in Marine Science

doi 10.3389/fmars.2025.1572772

699 views

Study Protocol

Published on 01 Oct 2025

Safety and feasibility of cerebrolysin in treatment of primary intracerebral hemorrhage (CLINCH)—a prospective, randomized, open-label, blinded endpoint pilot trial

in Stroke

Adam Kobayashi
Kinga Rutkowska
Katarzyna Gocyla-Dudar
Beata Chelstowska
Natalia Pozarowszczyk
Michal Karlinski

Frontiers in Neurology

doi 10.3389/fneur.2025.1602956

352 views

Articles

Targeting the CCL28-STAT3-PLAC8 axis to suppress metastasis and remodel tumor microenvironment in colorectal cancer

Elucidating the multiscale mechanisms and therapeutic targets of caffeic acid in gastric cancer: a synergy of computational and experimental approaches

Environmental sustainability, an essential outcome for implementation scientists to improve health

High-content stimulated Raman pathology imaging and transcriptomics reveal leukemia subtype-specific lipid metabolic heterogeneity

Structural elucidation of Langat virus helicase unveils dual-target inhibition for broad-spectrum anti-flaviviruses strategy

Gut microbiota in hypothyroidism: pathogenic mechanisms and opportunities for precision microbiome interventions

Advances in drug delivery systems for the management of gout and hyperuricemia

Risk factors for postherpetic neuralgia: a meta-analysis based on demographic, clinical features, and treatment characteristics

Advances in WRKY regulation of immune responses in medicinal plants

Cost-effectiveness of HLX01 (Hanlikang®) vs. rituximab combined with CHOP in treatment-naive diffuse large B-Cell lymphoma: a partitioned survival model analysis

Impact of using supplemented thylakoids derived from spinach for 12 weeks of high-intensity functional training on adipo-myokines in obese males

From liberal paralysis to green republican resolution? Conceptualising, illustrating, and addressing problems of governability in eco-social politics

Using drama in café dialogue as an alternative approach in multicultural educational processes

The more you play, the better you feel: a dose–response analysis of pickleball and mental wellbeing in U.S. adults

Conflict, cod and Calanus: can technology increase trust in management of a contested fishery?

Safety and feasibility of cerebrolysin in treatment of primary intracerebral hemorrhage (CLINCH)—a prospective, randomized, open-label, blinded endpoint pilot trial

Impact of using supplemented thylakoids derived from spinach for 12 weeks of high-intensity functional training on adipo-myokines in obese males