Smooth Function | List of Frontiers open access articles

Brief Research Report

Published on 13 May 2026

Serplulimab combined with gemcitabine, nab-paclitaxel, and stereotactic body radiotherapy versus gemcitabine and nab-paclitaxel as first-line treatment for recurrent or metastatic pancreatic ductal adenocarcinoma: a randomized, open-label, multicenter, phase III clinical trial (WGOG-PAN 006/ICSBR-2)

in Cancer Immunity and Immunotherapy

Xin Wang
Pei Zhang
Dan Cao
Huanji Xu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1817221

190 views

Original Research

Published on 13 May 2026

From risk factors to molecular targets: clinical associations and molecular docking insights into phthalate-associated diabetic retinopathy

in Ophthalmology

Zhiwei Xu
Shi Bai
Caidi He
Xiaobei Lv
Qin Li
Qile Mao
Haijian Wu
Peter Wang

Frontiers in Medicine

doi 10.3389/fmed.2026.1792532

174 views

Original Research

Published on 13 May 2026

Buprenorphine extended-release (Ethiqa XR) impacts the immunological response in mice exposed to aerosolized Burkholderia pseudomallei or Yersinia pestis

in Comparative Immunology

Carlos I. Rodriguez
Christopher P. Klimko
Michael L. Davies
Jennifer L. Dankmeyer
Nathaniel O. Rill
Melissa Hunter
Brian A. Smith
Taloria K. Wheeler
Wendy M. Webster-Zahnow
Andre M. Swamotz

Frontiers in Immunology

doi 10.3389/fimmu.2026.1823747

339 views

Original Research

Published on 13 May 2026

Predictor and subgroup analysis of somatic symptoms and emotional exhaustion among university students in Germany during the SARS-CoV-2 pandemic: a longitudinal analysis

in Public Health Education and Promotion

Katharina Wörle
Pavel Dietz
Stephan Letzel
Thomas Rigotti
Lina M. Mülder
Jennifer L. Reichel

Frontiers in Public Health

doi 10.3389/fpubh.2026.1827225

242 views

Systematic Review

Published on 13 May 2026

The preventive effect of sodium-glucose co-transporter-2 inhibitors on life-threatening arrhythmias in patients with chronic kidney disease: a meta-analysis

in Cardiac Rhythmology

Qian Yang
Yongjian Jia
Zhuodong Li
Yanmin Yu
Yi Dang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1781810

340 views

Original Research

Published on 13 May 2026

Hematological, inflammatory, and hypoxia-responsive adaptations to 18-day normobaric live high-train low training in elite rowers

in Exercise Physiology

Anna Kasperska
Hanna Dziewiecka
Wojciech Jankowski
Tomasz Mikulski
Ireneusz Czerniec
Anna Skarpańska-Stejborn
Joanna Ostapiuk-Karolczuk

Frontiers in Physiology

doi 10.3389/fphys.2026.1834329

328 views

Original Research

Published on 13 May 2026

Metagenomic sequencing reveals structural and functional differentiation of rhizosphere bacterial communities driven by nitrogen and potassium deficiency associated with root rot of Schisandra chinensis

in Terrestrial Microbiology

Li Li
Ruibo Liu
Hao Yang
Yongping Zhao

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1827096

196 views

Original Research

Published on 13 May 2026

Interfacial bonding mechanisms and physicochemical evolution at the reclaimed asphalt pavement aggregates-cement interface

in Construction Materials

Jisheng Wang
Haidong Ji

Frontiers in Built Environment

doi 10.3389/fbuil.2026.1821357

230 views

Original Research

Published on 13 May 2026

Mesenchymal stem cell alleviate concanavalin A-induced hepatitis via immune reprogramming and complement regulation

in Immunological Tolerance and Regulation

Hanpeng Luo
Bing Liu
Yaqin Li
Peng Cui
Tao Zhou
Cai Ye
Can Wu
Junchang Wu
Yu Wang
Wei V. Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2026.1809194

313 views

Original Research

Published on 13 May 2026

Hyperthermia enhances the efficacy of PD-1 inhibitor plus chemotherapy in PD-L1 CPS-negative advanced gastric cancer

in Cancer Immunity and Immunotherapy

Weihang Li
Xin Sun
Ping Li
Ting Wang
Panling Xu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1795363

160 views

Systematic Review

Published on 13 May 2026

Sustainability-aligned digital risks in South African higher education: a systematic review (2019–2025)

in Higher Education

Bakang Nthutang
Mampilo Phahlane

Frontiers in Education

doi 10.3389/feduc.2026.1821997

227 views

Brief Research Report

Published on 13 May 2026

Service-learning and civic competencies development: a quasi-experimental study between private higher education institutions in Ecuador and Chile

in Higher Education

Karla Díaz
Chenda Ramírez
Sol Palacios
Nascira Ramia
Luz María Jeria

Frontiers in Education

doi 10.3389/feduc.2026.1746730

216 views

Original Research

Published on 13 May 2026

Analysis of the association between water iodine concentration and TyG-BMI index with thyroid diseases: a cross-sectional study in Shandong province, China

in Nutritional Epidemiology

Chun-Hu Li
Meng Zhao
Tong Zhao
Yu-Hang Liu
Zong-Yu Yue
Zhe-Xu Zhang
Xiang-Kun Zeng
Dian-Jun Sun
Peng Liu

Frontiers in Nutrition

doi 10.3389/fnut.2026.1819662

180 views

Original Research

Published on 13 May 2026

Incremental value of placental miR-7641 and ferroptosis-related phenotypes in risk stratification of severe preeclampsia

in Clinical and Translational Physiology

Huihui Hu
Rumin Wang
Xiaodi Wang
Min Hu

Frontiers in Physiology

doi 10.3389/fphys.2026.1834708

249 views

Review

Published on 13 May 2026

Peripheral retinal degenerations: multimodal imaging–guided risk stratification and clinical decision-making

in Retina

Siniša Babović
Nemanja Maletin
Nikola Denda

Frontiers in Ophthalmology

doi 10.3389/fopht.2026.1814997

1,219 views

Review

Published on 13 May 2026

Comparative effectiveness of high-intensity interval training versus moderate-intensity continuous training in patients with type 2 diabetes mellitus: a systematic review and meta-analysis

in Clinical Diabetes

Pengbo Ren
Jian Zhang
Shi Li
Tingwen Li

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1833684

461 views

Articles

From risk factors to molecular targets: clinical associations and molecular docking insights into phthalate-associated diabetic retinopathy

Buprenorphine extended-release (Ethiqa XR) impacts the immunological response in mice exposed to aerosolized Burkholderia pseudomallei or Yersinia pestis

Predictor and subgroup analysis of somatic symptoms and emotional exhaustion among university students in Germany during the SARS-CoV-2 pandemic: a longitudinal analysis

The preventive effect of sodium-glucose co-transporter-2 inhibitors on life-threatening arrhythmias in patients with chronic kidney disease: a meta-analysis

Hematological, inflammatory, and hypoxia-responsive adaptations to 18-day normobaric live high-train low training in elite rowers

Metagenomic sequencing reveals structural and functional differentiation of rhizosphere bacterial communities driven by nitrogen and potassium deficiency associated with root rot of Schisandra chinensis

Interfacial bonding mechanisms and physicochemical evolution at the reclaimed asphalt pavement aggregates-cement interface

Mesenchymal stem cell alleviate concanavalin A-induced hepatitis via immune reprogramming and complement regulation

Hyperthermia enhances the efficacy of PD-1 inhibitor plus chemotherapy in PD-L1 CPS-negative advanced gastric cancer

Sustainability-aligned digital risks in South African higher education: a systematic review (2019–2025)

Service-learning and civic competencies development: a quasi-experimental study between private higher education institutions in Ecuador and Chile

Analysis of the association between water iodine concentration and TyG-BMI index with thyroid diseases: a cross-sectional study in Shandong province, China

Incremental value of placental miR-7641 and ferroptosis-related phenotypes in risk stratification of severe preeclampsia

Peripheral retinal degenerations: multimodal imaging–guided risk stratification and clinical decision-making

Comparative effectiveness of high-intensity interval training versus moderate-intensity continuous training in patients with type 2 diabetes mellitus: a systematic review and meta-analysis