Spatial Optimism | List of Frontiers open access articles

Original Research

Accepted on 15 May 2026

Multi-omics profiling reveals an auxin–salicylic acid signaling hub driving flavonoid depletion and accelerated vigor loss in tetraploid Chinese cabbage seeds

in Genomics of Plants and Plant-Associated Organisms

Chuan Meng
Xiaodong Liu
Fang Wu
Xiao Chao Ma
Xiaoshan Chen
Lei Ma
Mingqiu Wang

Frontiers in Genetics

Editorial

Accepted on 15 May 2026

Beyond Energy Production: Exploring Mitochondrial Dynamics and Disease

in Cell Death and Survival

Nahid A Khan
Ruben Torregrosa

Frontiers in Cell and Developmental Biology

Brief Research Report

Accepted on 15 May 2026

Clinical Heterogeneity and Diagnostic Challenges in CASK-Related Neurodevelopmental Disorders: A Longitudinal Observational Study

in Intellectual Disabilities

Iliyana Hristova Pacheva
Elena Timova
Tihomir Todorov
Iglika Sotkova
Katerina Gaberova
Ralitza Yordanova
Tzvetelina Tzvetanova
Fani Galabova
Nevjana Ivanova
Albena Todorova

Frontiers in Psychiatry

Original Research

Accepted on 15 May 2026

Moderate organic–inorganic fertilization optimizes soybean productivity by reshaping rhizosphere microbiome–metabolite networks

in Crop and Product Physiology

Jing Zhang
Qiang Liu
Jiali Chen
Yongmei Zhou
Bian Hong Zhang
Zhaonian Yuan
Peiwu Li
Ziqin Pang

Frontiers in Plant Science

Review

Accepted on 15 May 2026

Parkinson's Disease Beyond Motor Symptoms: A Review of the Validity and Limitations of Current Classification of Non-Motor Symptoms

in Aging Psychiatry

Asad Makhani
Tiago Mestre
Anne-Mary Abe

Frontiers in Psychiatry

Original Research

Accepted on 15 May 2026

Impact of Hospice Care Plus Estazolam on Sleep and Psychological Distress in Advanced Gastrointestinal Cancer: A Real-World Observational Study

in Gastroenterology

Lihong Hu
Donghui Cao
Xiaoya Yuan
Xiangtuan Wang
Haifeng Yuan

Frontiers in Medicine

Case Report

Accepted on 15 May 2026

Case Report: Cutaneous Niche-Restricted Malignant Phenotypes in PTCL-NOS Revealed by Single-Cell Sequencing

in Skin Cancer

Shucheng Zhang
Zhuqing Li
Yang Lin
Xiaoyue Sun
Meng Qiao
Xiaoqing Si

Frontiers in Oncology

Original Research

Accepted on 15 May 2026

Safety Signals of Perfluorohexyloctane Ophthalmic Solution in Patients with Dry Eye Disease

in Ophthalmology

Zhengtai Sun
Yuting Liu
Lijuan Que

Frontiers in Medicine

Original Research

Accepted on 15 May 2026

Nomograms to predict severe PH and survival in COPD patients using noninvasive parameters

in Pulmonary Medicine

Xingxing Sun
Yuan Cao
Hanqing Zhu
Jianhua Xu
Bigyan Pudasaini
Wenlan Yang
Jinming Liu
Jian Guo

Frontiers in Medicine

Original Research

Accepted on 15 May 2026

Dynamic Changes in Carbon Storage in the Lower Yalong River Basin During Cascade Hydropower Development

in Land Cover and Land Use Change

Borui Wang
Yuanyuan WANG
Zhiwen Dong
Yumin Zhao

Frontiers in Remote Sensing

Original Research

Accepted on 15 May 2026

Explainable Deep Learning for Healthcare Workforce Attrition: A Methodological Study on the Watson Healthcare Synthetic Benchmark

in Occupational Health and Safety

Xinyu Lu
Dan Yin
Tingyi Mei

Frontiers in Public Health

Case Report

Accepted on 15 May 2026

Case Report: Endoscopic geometric remodeling for angulation-type efferent loop stenosis after pancreaticoduodenectomy

in Gastroenterology

Donghai Wu
Jiahuang Huang
Shihua Ding
Na Li
Weitao Wu

Frontiers in Medicine

Mini Review

Accepted on 15 May 2026

Cell type-specific pharmacological modulation of the neuro-immune axis: The role of ADRB2 signaling in reshaping the tumor ecosystem

in Pharmacology of Anti-Cancer Drugs

Wenjun Meng
Mengting Li
Ruoyu Ren
Xiaoli Mu
Bin Hou
Qing Li

Frontiers in Pharmacology

Review

Accepted on 15 May 2026

Enhancing Targeted Strategies for Cancer Immunotherapy by Elucidating mRNA Processing Mechanisms

in Cancer Immunity and Immunotherapy

Zhihao Chen
Xiao Lu
Wenwen Gan
Jiang Yuan

Frontiers in Immunology

Original Research

Accepted on 15 May 2026

Predicting preoperative axillary lymph node metastasis to guide surgical decisions in invasive breast cancer

in Breast Cancer

Qi Xin
治琳杨

Frontiers in Oncology

Review

Accepted on 15 May 2026

Natural Products Reshape Osteosarcoma Cell Fate: Promoting Cell Death

in Pharmacology of Anti-Cancer Drugs

Binghan Yan
Junli Chang
Peng Zhao
Xingyuan Sun
Suxia Guo
Yanping Yang

Frontiers in Pharmacology

Articles

Multi-omics profiling reveals an auxin–salicylic acid signaling hub driving flavonoid depletion and accelerated vigor loss in tetraploid Chinese cabbage seeds

Beyond Energy Production: Exploring Mitochondrial Dynamics and Disease

Clinical Heterogeneity and Diagnostic Challenges in CASK-Related Neurodevelopmental Disorders: A Longitudinal Observational Study

Moderate organic–inorganic fertilization optimizes soybean productivity by reshaping rhizosphere microbiome–metabolite networks

Parkinson's Disease Beyond Motor Symptoms: A Review of the Validity and Limitations of Current Classification of Non-Motor Symptoms

Impact of Hospice Care Plus Estazolam on Sleep and Psychological Distress in Advanced Gastrointestinal Cancer: A Real-World Observational Study

Case Report: Cutaneous Niche-Restricted Malignant Phenotypes in PTCL-NOS Revealed by Single-Cell Sequencing

Safety Signals of Perfluorohexyloctane Ophthalmic Solution in Patients with Dry Eye Disease

Nomograms to predict severe PH and survival in COPD patients using noninvasive parameters

Dynamic Changes in Carbon Storage in the Lower Yalong River Basin During Cascade Hydropower Development

Explainable Deep Learning for Healthcare Workforce Attrition: A Methodological Study on the Watson Healthcare Synthetic Benchmark

Case Report: Endoscopic geometric remodeling for angulation-type efferent loop stenosis after pancreaticoduodenectomy

Cell type-specific pharmacological modulation of the neuro-immune axis: The role of ADRB2 signaling in reshaping the tumor ecosystem

Enhancing Targeted Strategies for Cancer Immunotherapy by Elucidating mRNA Processing Mechanisms

Predicting preoperative axillary lymph node metastasis to guide surgical decisions in invasive breast cancer

Natural Products Reshape Osteosarcoma Cell Fate: Promoting Cell Death