Sub Chronic Toxicity | List of Frontiers open access articles

Original Research

Published on 23 Apr 2014

Dose and time-dependent sub-chronic toxicity study of hydroethanolic leaf extract of Flabellaria paniculata Cav. (Malpighiaceae) in rodents

in Ethnopharmacology

Abidemi J. Akindele
Adejuwon A. Adeneye
Oluwole S. Salau
Margaret O. Sofidiya
Adokiye S. Benebo

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00078

8,947 views
59 citations

Original Research

Published on 20 Nov 2025

Evaluation of long-term safety profile of an EU-GMP certified Cannabis sativa L. strain in a naturally aging preclinical model

in Ethnopharmacology

Gabriela-Dumitrita Stanciu
Ivona Costachescu
Daniela-Carmen Ababei
Andrei Szilagyi
Raluca-Maria Gogu
Vlad-Constantin Craciun
Andrei-Daniel Timofte
Irina-Draga Caruntu
Cristina-Elena Dobre
Bogdan-Ionel Tamba

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1716366

1,145 views

Original Research

Published on 28 Sep 2022

Acute, chronic, and genotoxic studies on the protopine total alkaloids of the Macleaya cordata (willd.) R. Br. in rodents

in Predictive Toxicology

Zhen Dong
Shu-sheng Tang
Xiao-lan Ma
Bin Tan
Zhao-shan Tang
Chang-hong Li
Zi-hui Yang
Jian-guo Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2022.987800

3,424 views
11 citations

Original Research

Published on 20 Aug 2021

Citrus Segment Degradation Potential, Enzyme Safety Evaluation, and Whole Genome Sequence of Aspergillus aculeatus Strain ZC-1005

in Food Microbiology

Jieyi Wang
Zhipeng Gao
Yujiao Qian
Xiao Hu
Gaoyang Li
Fuhua Fu
Jiajing Guo
Yang Shan

Frontiers in Microbiology

doi 10.3389/fmicb.2021.671200

3,374 views
6 citations

Review

Published on 14 Oct 2016

Prediction of the Carcinogenic Potential of Human Pharmaceuticals Using Repeated Dose Toxicity Data and Their Pharmacological Properties

in Regulatory Science

Jan Willem van der Laan
Wenny H. W. Buitenhuis
Laura Wagenaar
Ans E. M. F. Soffers
Eugene P. van Someren
Cyrille A. M. Krul
Ruud A. Woutersen

Frontiers in Medicine

doi 10.3389/fmed.2016.00045

9,634 views
30 citations

Original Research

Published on 26 Sep 2018

28-Day Oral Chronic Toxicity Study of Arctigenin in Rats

in Predictive Toxicology

Yu-jun Tan
Yu-shan Ren
Lei Gao
Lan-fang Li
Li-juan Cui
Bin Li
Xin Li
Jian Yang
Ming-zhi Wang
Yuan-yuan Lv

Frontiers in Pharmacology

doi 10.3389/fphar.2018.01077

9,016 views
27 citations

Original Research

Published on 06 Feb 2024

Sustained silencing peanut allergy by xanthopurpurin is associated with suppression of peripheral and bone marrow IgE-producing B cell

in Nutritional Immunology

Nan Yang
Kamal Srivastava
Yujuan Chen
Hang Li
Anish Maskey
Patrick Yoo
Xiaohong Liu
Raj K. Tiwari
Jan Geliebter
Anna Nowak-Wegrzyn

Frontiers in Immunology

doi 10.3389/fimmu.2024.1299484

6,953 views
1 citation

Articles

Dose and time-dependent sub-chronic toxicity study of hydroethanolic leaf extract of Flabellaria paniculata Cav. (Malpighiaceae) in rodents

Evaluation of long-term safety profile of an EU-GMP certified Cannabis sativa L. strain in a naturally aging preclinical model

Acute, chronic, and genotoxic studies on the protopine total alkaloids of the Macleaya cordata (willd.) R. Br. in rodents

Citrus Segment Degradation Potential, Enzyme Safety Evaluation, and Whole Genome Sequence of Aspergillus aculeatus Strain ZC-1005

Prediction of the Carcinogenic Potential of Human Pharmaceuticals Using Repeated Dose Toxicity Data and Their Pharmacological Properties

28-Day Oral Chronic Toxicity Study of Arctigenin in Rats

Sustained silencing peanut allergy by xanthopurpurin is associated with suppression of peripheral and bone marrow IgE-producing B cell