Therapeutic Algorithm | List of Frontiers open access articles

Original Research

Published on 01 Aug 2025

SARS-CoV-2 XBB.1.5 infects wild-type C57BL/6 mice and induces a protective CD4+ T cell response required for viral clearance

in Virus and Host

Amany Elsharkawy
Chinonye Dim
Chunyu Ge
Lila D. Patterson
Zainab Nabi
Mukesh Kumar

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1621226

566 views

Original Research

Published on 01 Aug 2025

Lymphedema pathogenesis involves antigen-driven expansion of CD4+ T cells in skin

in T Cell Biology

Adana-Christine Campbell
Annica R. Stull-Lane
Jung Eun Baik
Ananta Sarker
Jinyeon Shin
Gopika Ashokan
Hyeung Ju Park
Bracha L. Pollack
Pradhi Pakkerakari
Yollanda Franco Parisotto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620571

572 views

Review

Published on 01 Aug 2025

Immunological microenvironment and targeted therapeutics in multiple sclerosis: new insights in crosstalk between immune niches and CNS

in Multiple Sclerosis and Neuroimmunology

Xiaodi Sun
Feng Zhang
Luojinyun Wang
Gyeore Lee
Sibo Yang
Daqiang Zhou
Bohao Chang
Bo Hu
Yifan Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604987

390 views

Original Research

Published on 01 Aug 2025

Immunoglobulin A carries sulfated and O-acetylated N-glycans primarily at the tailpiece site – strategies for site-specific N-glycan identification

in Glycoscience

Frania J. Zuniga-Banuelos
Greta Lemke
Marcus Hoffmann
Udo Reichl
Erdmann Rapp

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1595173

570 views

Original Research

Published on 01 Aug 2025

Research on the diagnosis model of osteoarthritis based on methylation-related genes using machine learning algorithms

in Computational Genomics

Xu Cui
Houlin Ji
Shengyang Guo
Ju Liu
Linyuan Zhang
Yongwei Jia
Yin Cui
Xiaoxiao Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1595676

439 views

Original Research

Published on 01 Aug 2025

Correlation study on the risk of cardiovascular adverse events in diabetic foot patients based on machine learning - a retrospective cohort study

in Clinical Diabetes

Liran Zheng
Jiageng Chen
Wenyan Xu
Min Ding
Juan Li
Fenghua Tian
Lei Zhang
Qianqian Li
Shuai Wang
Zeyu Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1595471

594 views

Community Case Study

Published on 01 Aug 2025

Establishing community partnerships to maintain social connection and healthcare access during an emergency declaration: virtual veterans socials

in Public Mental Health

Jay A. Gorman
Elizabeth S. Chamberlin
Helen P. Hailes
Marsha Langer Ellison
Rachelle M. Calixte
Jessica Mack
John Smolinsky
Erin D. Reilly
Charles E. Drebing

Frontiers in Public Health

doi 10.3389/fpubh.2025.1548618

433 views

Original Research

Published on 01 Aug 2025

Based on Bayesian multivariate skewed regression analysis: the interaction between skeletal muscle mass and left ventricular mass

in Exercise Physiology

Zhenchao Liu
Tianxiang Lei
Tianwei Liu
Yunliang Guo
Yun Wang
Yu Cao

Frontiers in Physiology

doi 10.3389/fphys.2025.1515560

240 views

Original Research

Published on 01 Aug 2025

Assessment of knowledge and awareness of monkeypox viral infection in Palestine: a community-based study

in Virus and Host

Nuha El Sharif
Muna Ahmead

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1584848

324 views

Original Research

Published on 01 Aug 2025

Towards fluid human-agent collaboration: From dynamic collaboration patterns to models of theory of mind reasoning

in Computational Intelligence in Robotics

Florian Schröder
Fabian Heinrich
Stefan Kopp

Frontiers in Robotics and AI

doi 10.3389/frobt.2025.1532693

1,990 views

Original Research

Published on 01 Aug 2025

Plasma inflammatory cytokines are associated with cognitive impairment after acute minor ischemic stroke and transient ischemic attack

in Inflammation

PanPan Zhao
Meng Zhao
GuiMei Zhang
WeiJie Zhai
YongChun Wang
YanXin Shen
Li Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1445938

287 views

Original Research

Published on 01 Aug 2025

The immunogenicity and safety of an inactivated quadrivalent influenza vaccine and a 23-valent pneumococcal polysaccharide vaccine in individuals with chronic diseases

in Vaccines and Molecular Therapeutics

Wanqin Tang
Xi Lu
Zhongkui Zhu
Dan Yu
Huaxian Liu
Yufei Song
Lu Shen
Yang Yu
Yanwei Zhao
Yan Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624095

530 views

Original Research

Published on 01 Aug 2025

Overexpression of NK4 gene in TU212 affects migratory activity in laryngeal squamous cell carcinoma

in Head and Neck Cancer

Yixuan Huo
Wei Zhang
Fan Yang
Wenhua Shao
Guozheng Cong
Shoukai Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1553626

355 views

Original Research

Published on 01 Aug 2025

Analysis of pathogenic bacteria and antimicrobial residues in bovine waste milk on dairy farms in southern Chile

in Veterinary Infectious Diseases

Fernando Ulloa
Martina Penati
José M. Hernández-Agudelo
Carlos Tejeda
Pamela Steuer
María Filippa Addis
Armin Mella
Nivia Canales
Juan Pablo Soto
Miguel Salgado

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1613185

615 views

Study Protocol

Published on 01 Aug 2025

Improving health and housing outcomes through a simulation and economic model: an evidence-based protocol of a group model building approach to develop an agent-based model

in Life-Course Epidemiology and Social Inequalities in Health

Danielle M. Kline
Pranav Padmanabhan
Sarah E. Brewer
Magdalena Cerdá
Elysia Versen
Katherine M. Keyes
Margot Kushel
Erin C. Wilson
Paul Wesson
Ayaz Hyder

Frontiers in Public Health

doi 10.3389/fpubh.2025.1623385

437 views

Original Research

Published on 01 Aug 2025

Institutional priorities and student engagement: a multi-stakeholder analysis of physical education in Israel

in Physical Education and Pedagogy

Ali Alayan
Ahmad Salhab
Paz Carmel
Ronit Ahdut HaCohen

Frontiers in Sports and Active Living

doi 10.3389/fspor.2025.1625231

526 views

Articles

SARS-CoV-2 XBB.1.5 infects wild-type C57BL/6 mice and induces a protective CD4+ T cell response required for viral clearance

Lymphedema pathogenesis involves antigen-driven expansion of CD4+ T cells in skin

Immunological microenvironment and targeted therapeutics in multiple sclerosis: new insights in crosstalk between immune niches and CNS

Immunoglobulin A carries sulfated and O-acetylated N-glycans primarily at the tailpiece site – strategies for site-specific N-glycan identification

Research on the diagnosis model of osteoarthritis based on methylation-related genes using machine learning algorithms

Correlation study on the risk of cardiovascular adverse events in diabetic foot patients based on machine learning - a retrospective cohort study

Establishing community partnerships to maintain social connection and healthcare access during an emergency declaration: virtual veterans socials

Based on Bayesian multivariate skewed regression analysis: the interaction between skeletal muscle mass and left ventricular mass

Assessment of knowledge and awareness of monkeypox viral infection in Palestine: a community-based study

Towards fluid human-agent collaboration: From dynamic collaboration patterns to models of theory of mind reasoning

Plasma inflammatory cytokines are associated with cognitive impairment after acute minor ischemic stroke and transient ischemic attack

The immunogenicity and safety of an inactivated quadrivalent influenza vaccine and a 23-valent pneumococcal polysaccharide vaccine in individuals with chronic diseases

Overexpression of NK4 gene in TU212 affects migratory activity in laryngeal squamous cell carcinoma

Analysis of pathogenic bacteria and antimicrobial residues in bovine waste milk on dairy farms in southern Chile

Improving health and housing outcomes through a simulation and economic model: an evidence-based protocol of a group model building approach to develop an agent-based model

Institutional priorities and student engagement: a multi-stakeholder analysis of physical education in Israel