Therapeutic Effecacy | List of Frontiers open access articles

Original Research

Accepted on 13 Jun 2025

TREM1 is Essential for Maintaining Stemness of Liver Cancer Stem-Like Cells in Hepatocellular Carcinoma

in Cancer Immunity and Immunotherapy

Arsha Sreekumar
Ashwin Ajith
Kenza Mamouni
Daniel D Horuzsko
Anatolij Horuzsko

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618342

Review

Accepted on 13 Jun 2025

Cardiac Involvement in Female Elite Athletes with Carriers Status of Duchenne Muscular Dystrophy

in Cardiovascular Epidemiology and Prevention

Simon Wernhart
Tom Kastner
Martin Halle
Stephan Mueller
Veronika Schmid
Cihan Akbulut
Cordula Wolf
Christian Meierhofer
Teresa Trenkwalder
Isabel Diebold

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1606994

Original Research

Accepted on 13 Jun 2025

Explainable Multi-View Transformer Framework with Mutual Learning for Precision Breast Cancer Pathology Image Classification

in Cancer Epidemiology and Prevention

Haewon Byeon
Mahmood Alsaadi
Richa Vijay
Purshottam J Assudani
Ashit Kumar Dutta
Monika Bansal
Pavitar Parkash Singh
Mukesh Soni
Mohammed Wasim Bhatt

Frontiers in Oncology

doi 10.3389/fonc.2025.1626785

Original Research

Accepted on 13 Jun 2025

Climate-resilient strategies for wheat farming: minimizing climate impact, optimizing productivity, and maximizing profitability in the subtropical agroecological landscape of India

in Climate-Smart Food Systems

Vijay Singh Meena
RAJ KUMAR JAT
Dr Shubham Durgude
S Kumar
R K Sohane
Ratnesh Kumar Jha
A KUmar
U Kumar
A Kumar
R N Singh

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1564812

Hypothesis and Theory

Accepted on 13 Jun 2025

Prolonged Post-Androgen Abuse Hypogonadism (PPAAH): Potential Mechanisms and a Proposed Standardized Diagnosis

in Reproduction

Joël van Os
Diederik L. Smit
Peter Bond
Willem de Ronde

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1621558

Original Research

Accepted on 13 Jun 2025

Global Burden of Chronic Kidney Disease and Its Attributable Risk Factors (1990-2021): An Analysis Based on the Global Burden of Disease Study

in Renal Endocrinology

Minjia Li
Hong-Yong Liu
Yun-Qiang Zhang
Sheng-Rong Li
Jian-Hong Zhang
Rong Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1563246

Original Research

Accepted on 13 Jun 2025

Efficiency of Structural Brain Networks Mediates Age-Associated Differences in Executive Functioning in Older Adults

in Neurocognitive Aging and Behavior

Geraldine Rodríguez-Nieto
Caroline Seer
Hamed Zivari Adab
Antonio Jiménez-Marín
Sima Chalavi
Amirhossein Rasooli
Jesus M Cortes
Stefan Sunaert
Stephan P Swinnen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1593868

Original Research

Accepted on 13 Jun 2025

Collective action under risk and uncertainty: assessing impacts on smallholder farmers' income and food security in Malawi

in Agricultural and Food Economics

Jinwon Suh
Seongtae Ji
Tabitha C Nindi-Chigwe

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1607329

Original Research

Accepted on 13 Jun 2025

Impact of Mung Bean Crop Market Participation on Asset Accumulation of Smallholder Households in Low Land Areas of South Ethiopia

in Agricultural and Food Economics

Girma Gata Ganebo
Berhanu Kuma
Alula Tafesse Shirko

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1562864

Original Research

Accepted on 13 Jun 2025

The potential of olfaction loss to induce cognitive impairment and anxiety behavior in mice via the microbiota-gut-brain axis

in Microorganisms in Vertebrate Digestive Systems

Xiangyu Zhao
Chao Xue
Yiming Wang
Xiwei Liu
Ran Li
Xianfeng Yi

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1595742

Editorial

Accepted on 13 Jun 2025

Editorial: Optimal Physical Activity Across the Lifespan for People of All Abilities

in Physical Activity in the Prevention and Management of Disease

David Arthur Hart
Ronald F Zernicke

Frontiers in Sports and Active Living

doi 10.3389/fspor.2025.1645447

Review

Accepted on 13 Jun 2025

Advances in Clinical Applications of Microneedle

in Drug Metabolism and Transport

Kequan Chen
Xinyu Sun
Yangkaiyuan Liu
Shiyu LI
Dianhuai Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1607210

Review

Accepted on 13 Jun 2025

Virtual Reality-Delivered Skills-Based Therapy for Chronic Lower Back Pain: From Proof-of-Concept to FDA Authorization to Clinical Implementation In-Home and Beyond

in Virtual Reality in Medicine

Todd Maddox
Josh Sackman
Matthew Stoudt
Michael Chibbaro
Emily Judge
Regan Rothery
Jesse Donini
Roselani Maddox
Beth D Darnall

Frontiers in Virtual Reality

doi 10.3389/frvir.2025.1613188

118 views

Original Research

Accepted on 13 Jun 2025

Research and optimization on the strength recovery mechanism of post peak fragmentation grouting reinforcement in mining rock mass

in Mechanics of Materials

Zhang Shuai
Sun Yao
Cao Jiantao
Lai Xingping
Wu Longquan

Frontiers in Materials

doi 10.3389/fmats.2025.1612050

Original Research

Accepted on 13 Jun 2025

Revealing Key Regulatory Factors in Lung adenocarcinoma: The Role of Epigenetic regulation of autophagy-related genes from Transcriptomics, scRNA-seq, and Machine Learning

in Pharmacology of Anti-Cancer Drugs

Zeng Xianchang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542338

Review

Accepted on 13 Jun 2025

Challenges of using tissue engineering methods in the treatment of hypospadias

in Biomaterials

Piotr Michal Wilczek
Dorota Bociaga
Adrianna Wierzbicka
Marek Krakos

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1611508

Articles

TREM1 is Essential for Maintaining Stemness of Liver Cancer Stem-Like Cells in Hepatocellular Carcinoma

Cardiac Involvement in Female Elite Athletes with Carriers Status of Duchenne Muscular Dystrophy

Explainable Multi-View Transformer Framework with Mutual Learning for Precision Breast Cancer Pathology Image Classification

Climate-resilient strategies for wheat farming: minimizing climate impact, optimizing productivity, and maximizing profitability in the subtropical agroecological landscape of India

Prolonged Post-Androgen Abuse Hypogonadism (PPAAH): Potential Mechanisms and a Proposed Standardized Diagnosis

Global Burden of Chronic Kidney Disease and Its Attributable Risk Factors (1990-2021): An Analysis Based on the Global Burden of Disease Study

Efficiency of Structural Brain Networks Mediates Age-Associated Differences in Executive Functioning in Older Adults

Collective action under risk and uncertainty: assessing impacts on smallholder farmers' income and food security in Malawi

Impact of Mung Bean Crop Market Participation on Asset Accumulation of Smallholder Households in Low Land Areas of South Ethiopia

The potential of olfaction loss to induce cognitive impairment and anxiety behavior in mice via the microbiota-gut-brain axis

Editorial: Optimal Physical Activity Across the Lifespan for People of All Abilities

Advances in Clinical Applications of Microneedle

Virtual Reality-Delivered Skills-Based Therapy for Chronic Lower Back Pain: From Proof-of-Concept to FDA Authorization to Clinical Implementation In-Home and Beyond

Research and optimization on the strength recovery mechanism of post peak fragmentation grouting reinforcement in mining rock mass

Revealing Key Regulatory Factors in Lung adenocarcinoma: The Role of Epigenetic regulation of autophagy-related genes from Transcriptomics, scRNA-seq, and Machine Learning

Challenges of using tissue engineering methods in the treatment of hypospadias