Tumor Cell Heterogeneity | List of Frontiers open access articles

Original Research

Published on 25 Jun 2025

Investigating the role of tumor cell heterogeneity and angiogenesis genes in the prognosis of multiple myeloma

in Cancer Immunity and Immunotherapy

Xue Qiao
Zhengrong Song
Li Geng
Lina Xing
Ying Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610833

2,604 views
2 citations

Original Research

Published on 12 Mar 2025

Single-cell and spatial transcriptomic analysis reveals tumor cell heterogeneity and underlying molecular program in colorectal cancer

in Systems Immunology

Teng Wang
Zhaoming Chen
Wang Wang
Heng Wang
Shenglong Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1556386

9,117 views
9 citations

Review

Published on 17 Feb 2023

Anti-ROR1 CAR-T cells: Architecture and performance

in Gene and Cell Therapy

Daniel Andrés Osorio-Rodríguez
Bernardo Armando Camacho
César Ramírez-Segura

Frontiers in Medicine

doi 10.3389/fmed.2023.1121020

14,547 views
19 citations

Original Research

Published on 12 Jan 2026

Single-cell transcriptomics reveals a novel mechanism of RDH16 regulating immune infiltration in hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Zhenzhen Zhang
Rui Fan
Jing Ma
Dehui Li
Yan Jiang
Fahui Liu
Qiming Gong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1689987

1,010 views

Case Report

Published on 30 May 2023

Case Report: An unclassified T cell lymphoma subtype with co-expression of TCR αβ and γ chains revealed by single cell sequencing

in Cancer Immunity and Immunotherapy

Wei Song
Gang Wang
Cheng Wang
Lulu Liu
Liming Zhang
Ruoyu Zhang
Haixi Zhang
Keqian Shi

Frontiers in Immunology

doi 10.3389/fimmu.2023.1184383

4,494 views
3 citations

Original Research

Published on 20 May 2025

Single-cell transcriptomics in colorectal cancer uncover the potential of metastasis and immune dysregulation of a cell cluster overexpressed PRSS22

in Cancer Immunity and Immunotherapy

Chengyuan Xu
Ziheng Zhou
Dongfei Zhu
Qingyun Zhang
Shoubin Zhong
Zhenhua Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586428

4,351 views
4 citations

Original Research

Published on 22 Sep 2025

Multiomics profiling identifies the poor prognostic role of a tumor cluster with GNA15 overexpression in triple-negative breast cancer

in Cancer Immunity and Immunotherapy

Guixin Wang
Junming Cao
Chenglu Lu
Yu Cao
Shuo Wang
Ziyi Chen
Zhaohui Chen
Yingxi Li
Yue Yu
Yao Tian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659183

3,482 views

Original Research

Published on 12 Jun 2025

Cross-cohort multi-omics analysis identifies novel clusters driven by EMT signatures in colorectal cancer

in Cancer Immunity and Immunotherapy

Wu Ning
Wenqing Jia
Jingyuan Ning
Lei Zhou
Zongze Li
Lin Zhang
Xin Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1628005

3,387 views
2 citations

Review

Published on 11 Jan 2024

Peroxisome proliferator-activated receptorα/γ agonist pioglitazone for rescuing relapsed or refractory neoplasias by unlocking phenotypic plasticity

in Cancer Molecular Targets and Therapeutics

Dennis Christoph Harrer
Florian Lüke
Tobias Pukrop
Lina Ghibelli
Christopher Gerner
Albrecht Reichle
Daniel Heudobler

Frontiers in Oncology

doi 10.3389/fonc.2023.1289222

4,837 views
5 citations

Articles

Investigating the role of tumor cell heterogeneity and angiogenesis genes in the prognosis of multiple myeloma

Single-cell and spatial transcriptomic analysis reveals tumor cell heterogeneity and underlying molecular program in colorectal cancer

Anti-ROR1 CAR-T cells: Architecture and performance

Single-cell transcriptomics reveals a novel mechanism of RDH16 regulating immune infiltration in hepatocellular carcinoma

Case Report: An unclassified T cell lymphoma subtype with co-expression of TCR αβ and γ chains revealed by single cell sequencing

Single-cell transcriptomics in colorectal cancer uncover the potential of metastasis and immune dysregulation of a cell cluster overexpressed PRSS22

Multiomics profiling identifies the poor prognostic role of a tumor cluster with GNA15 overexpression in triple-negative breast cancer

Cross-cohort multi-omics analysis identifies novel clusters driven by EMT signatures in colorectal cancer

Peroxisome proliferator-activated receptorα/γ agonist pioglitazone for rescuing relapsed or refractory neoplasias by unlocking phenotypic plasticity