Tumoroids | List of Frontiers open access articles

Original Research

Published on 27 Aug 2025

Laboratory-derived inflammatory ratios as a novel diagnostic model for premature coronary artery disease

in Cardiovascular Endocrinology

Fujia Guo
Min Xu
Qingxian Tu
Heyun Yang
Keqiang Linghu
Botao Li
Jie Zhang
Ya Luo
Hong Huang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1646944

173 views

Original Research

Published on 27 Aug 2025

Isolated hypoxic pelvic perfusion combined with electroporation is a valid alternative to traditional therapies for anal squamous cell carcinoma: a case study

in Gastrointestinal Cancers: Colorectal Cancer

Karl R. Aigner
Kornelia Aigner
Marc J. H. Hendrikx
Abderrahmane Bekrentchir
Hansjörg Aust

Frontiers in Oncology

doi 10.3389/fonc.2025.1644317

152 views

Original Research

Published on 27 Aug 2025

The impact of multistrain probiotics (Leuconostoc mesenteroides, Lactococcus lactis) on African catfish (Clarias gariepinus) gut microbiota, immunological response, and growth performance

in Comparative Immunology

Assel Paritova
Altay Ussenbayev
Rauan Abdessan
Zhenisgul Seitkaliyevna Assauova
Gulnur Berikovna Kuzembekova
Gulzhan Omarbekova
Aiken Sansyzbaevna Karabassova
Aigul Jenisbekkyzy Kassen
Zhuldyzay Kenzhebekova
Gulmira Alibayevna Abulgazimova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625199

201 views

Case Report

Published on 27 Aug 2025

Sorafenib-to-regorafenib sequence-induced atherosclerotic cardiovascular disease: a novel case report

in Cardio-Oncology

Changli Xu
Xianghua Quan
Qie Guo
Donghua Liu
Cheng Lu
Xue Yang
Wen Xu
Fanbo Jin
Haijun Qu
Hongyan Ji

Frontiers in Oncology

doi 10.3389/fonc.2025.1615472

193 views

Brief Research Report

Published on 27 Aug 2025

E-cigarette vapor amplifies neutrophilic inflammation and proteolytic EVs in response to LPS

in Inflammation

Lawrence W. Rasmussen
Dakota C. Finley
Julian B. Smith
Aaron S. Noa
J. Edwin Blalock
Amit Gaggar
Matthew C. Madison

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665936

168 views

Original Research

Published on 27 Aug 2025

The hypusine pathway in Ixodes ricinus: molecular cloning and validation of deoxyhypusine synthase as a novel target for drug discovery to treat and prevent vector borne diseases

in Parasite and Host

Annette Kaiser
Enzo Agostinelli
Dimitrios Tsikas

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1638906

102 views

Original Research

Published on 27 Aug 2025

Development and validation of a prognostic nomogram for unresectable pancreatic ductal adenocarcinoma with synchronous liver metastases: a study based on the SEER database and an external cohort

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Lu Huan
Qi He
Yang Cao
Changan Liu
Yue Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1636715

133 views

Original Research

Published on 27 Aug 2025

Epidemiological research on diabetic nephropathy at global, regional, and national levels from 1990 to 2021: an analysis derived from the global burden of disease 2021 study

in Clinical Diabetes

Lu Zhang
Liangliang Jiang
Rong Xu
Xuemei Zhang
Boxun Zhang
Rensong Yue

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1647064

224 views

Original Research

Published on 27 Aug 2025

CEACAM6 as a machine learning derived immune biomarker for predicting neoadjuvant chemotherapy response in HR+/HER2− breast cancer

in Systems Immunology

Dalang Fang
Jie Lin
Jin Wang
Qingxiao Nong
Shouwen Tao
Bimin Lu
Yanrong Yu
Hao Peng
Yingying Tian
Qunying Su

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662004

322 views

General Commentary

Published on 27 Aug 2025

Commentary: PLGA nanoparticles as an efficient carrier in Toxoplasma GAP45: a more effective vaccine against acute toxoplasmosis than traditional ones

in Parasite Immunology

Nathkapach Kaewpitoon Rattanapitoon
Patpicha Arunsan
Nav La
Khristine Laguador Sandoval
Schawanya Kaewpitoon Rattanapitoon

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663012

269 views

Original Research

Published on 27 Aug 2025

Association of neonatal hypothermia with neonatal hypoglycemia

in Pediatric Endocrinology

Henrike Hoermann
Marcia Roeper
Lisa Friesl
Calvin Kurz
Juliane Tautz
Mark Dzietko
Ertan Mayatepek
Thomas Meissner
Sebastian Kummer

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1641140

628 views

Original Research

Published on 27 Aug 2025

A novel prognostic biomarker DUSP6 promote the malignant progression of bladder cancer through mTOR mediated mitophagy

in Genitourinary Oncology

Jianbiao Huang
Chongwei Zhou
Zhaojun Yu
Zhen Song
Huanhuan Deng
Haichao Chao
Tao Zeng

Frontiers in Oncology

doi 10.3389/fonc.2025.1603069

164 views

Review

Published on 27 Aug 2025

Immunotherapy resistance in triple-negative breast cancer: Molecular mechanisms, tumor microenvironment, and therapeutic implications

in Breast Cancer

Zijian Zhou
Qin Zhou

Frontiers in Oncology

doi 10.3389/fonc.2025.1630464

168 views

Mini Review

Published on 27 Aug 2025

Endothelial activation in thromboangiitis obliterans: mechanisms and therapeutic horizons

in Inflammation

Wanting Wang
Siyao Chang
Gang Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1668203

185 views

Review

Published on 27 Aug 2025

Immunological mechanisms in Meniere’s disease

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Vincent G. Yuan
Anping Xia
Peter L. Santa Maria

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639916

172 views

Original Research

Published on 27 Aug 2025

A genetically determined molecular switch modulates the anti-inflammatory potential of human IgA

in Inflammation

Andrew W. Gibson
Jianming Wu
R. Curtis Hendrickson
Travis Ptacek
James Mobley
Jeffrey C. Edberg
Robert P. Kimberly

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641351

162 views

Articles

Laboratory-derived inflammatory ratios as a novel diagnostic model for premature coronary artery disease

Isolated hypoxic pelvic perfusion combined with electroporation is a valid alternative to traditional therapies for anal squamous cell carcinoma: a case study

The impact of multistrain probiotics (Leuconostoc mesenteroides, Lactococcus lactis) on African catfish (Clarias gariepinus) gut microbiota, immunological response, and growth performance

Sorafenib-to-regorafenib sequence-induced atherosclerotic cardiovascular disease: a novel case report

E-cigarette vapor amplifies neutrophilic inflammation and proteolytic EVs in response to LPS

The hypusine pathway in Ixodes ricinus: molecular cloning and validation of deoxyhypusine synthase as a novel target for drug discovery to treat and prevent vector borne diseases

Development and validation of a prognostic nomogram for unresectable pancreatic ductal adenocarcinoma with synchronous liver metastases: a study based on the SEER database and an external cohort

Epidemiological research on diabetic nephropathy at global, regional, and national levels from 1990 to 2021: an analysis derived from the global burden of disease 2021 study

CEACAM6 as a machine learning derived immune biomarker for predicting neoadjuvant chemotherapy response in HR+/HER2− breast cancer

Commentary: PLGA nanoparticles as an efficient carrier in Toxoplasma GAP45: a more effective vaccine against acute toxoplasmosis than traditional ones

Association of neonatal hypothermia with neonatal hypoglycemia

A novel prognostic biomarker DUSP6 promote the malignant progression of bladder cancer through mTOR mediated mitophagy

Immunotherapy resistance in triple-negative breast cancer: Molecular mechanisms, tumor microenvironment, and therapeutic implications

Endothelial activation in thromboangiitis obliterans: mechanisms and therapeutic horizons

Immunological mechanisms in Meniere’s disease

A genetically determined molecular switch modulates the anti-inflammatory potential of human IgA