Tumour Heterogeneity | List of Frontiers open access articles

Original Research

Published on 15 Feb 2022

Radiomic Analysis of Tumour Heterogeneity Using MRI in Head and Neck Cancer Following Chemoradiotherapy: A Feasibility Study

in Head and Neck Cancer

Amrita Guha
Mustafa Anjari
Gary Cook
Vicky Goh
Steve Connor

Frontiers in Oncology

doi 10.3389/fonc.2022.784693

3,098 views
6 citations

Review

Published on 31 Jul 2024

Advances in hepatocellular carcinoma drug resistance models

in Hepatobiliary Diseases

Yien Xiang
Jun Wu
Hanjiao Qin

Frontiers in Medicine

doi 10.3389/fmed.2024.1437226

4,538 views
3 citations

Review

Accepted on 14 Jan 2026

The mechanism of action, clinical significance, and research progress of tumor antigen-specific T cells in the treatment of HCC

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Liu Liu
Wang Tao
Lu Wei
Li Hongwei

Frontiers in Oncology

150 views

Review

Published on 12 Aug 2022

Patient-derived cancer models: Valuable platforms for anticancer drug testing

in Molecular and Cellular Oncology

Sofia Genta
Bryan Coburn
David W. Cescon
Anna Spreafico

Frontiers in Oncology

doi 10.3389/fonc.2022.976065

8,743 views
29 citations

Review

Published on 15 Mar 2022

Clinical Applications of Circulating Tumour Cells and Circulating Tumour DNA in Non-Small Cell Lung Cancer—An Update

in Thoracic Oncology

Joanna Kapeleris
Majid Ebrahimi Warkiani
Arutha Kulasinghe
Ian Vela
Liz Kenny
Rahul Ladwa
Kenneth O’Byrne
Chamindie Punyadeera

Frontiers in Oncology

doi 10.3389/fonc.2022.859152

9,571 views
29 citations

Review

Published on 30 Oct 2024

Radioresistance and brain metastases: a review of the literature and applied perspective

in Radiation Oncology

Andrew Youssef
Arjun Sahgal
Sunit Das

Frontiers in Oncology

doi 10.3389/fonc.2024.1477448

5,396 views
8 citations

Review

Published on 11 Mar 2025

Therapies targeting triple-negative breast cancer: a perspective on anti-FGFR

in Cancer Molecular Targets and Therapeutics

Jinhao Chen
Qianru Wang
Hongyan Wu
Xiaofei Huang
Chunyu Cao

Frontiers in Oncology

doi 10.3389/fonc.2024.1415820

4,933 views
1 citation

Original Research

Accepted on 26 Feb 2026

Osteosarcoma 3D patient derived cultures to test genome-informed personalized treatment options; a feasibility study

in Translational Medicine

Ieva Palubeckaite
Sanne Venneker
Natasja Franceschini
Pauline Wijers-Koster
Cedrick Agaser
Inge Briaire-de Bruijn
Alwine Kruisselbrink
Brendy van den Akker
Hailiang Mei
Anne-Marie Cleton-Jansen

Frontiers in Medicine

Original Research

Published on 13 May 2024

Expression of the apelin receptor, a novel potential therapeutic target, and its endogenous ligands in diverse stem cell populations in human glioblastoma

in Neuropharmacology

Thomas L. Williams
Peter Nwokoye
Rhoda E. Kuc
Kieran Smith
Anna L. Paterson
Kieren Allinson
Janet J. Maguire
Anthony P. Davenport

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1379658

3,734 views
8 citations

Original Research

Published on 29 Oct 2025

MRI-based radiomics for noninvasive prediction of T790M resistance mutation in lung cancer spinal metastases: an exploratory study

in Cancer Cell Biology

Xiaoya Zhou
Jiashi Zheng
Hua Ai
Chunna Yang
Jiahui Wang
Yiyao Sun
Lijun Jin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1673498

1,389 views

Review

Published on 25 Mar 2022

Novel Ex Vivo Models of Epithelial Ovarian Cancer: The Future of Biomarker and Therapeutic Research

in Cancer Molecular Targets and Therapeutics

James Clark
Christina Fotopoulou
Paula Cunnea
Jonathan Krell

Frontiers in Oncology

doi 10.3389/fonc.2022.837233

7,318 views
13 citations

Original Research

Published on 14 Oct 2021

Single-Cell RNA Sequencing in Multiple Pathologic Types of Renal Cell Carcinoma Revealed Novel Potential Tumor-Specific Markers

in Cancer Genetics

Cheng Su
Yufang Lv
Wenhao Lu
Zhenyuan Yu
Yu Ye
Bingqian Guo
Deyun Liu
Haibiao Yan
Tianyu Li
Qingyun Zhang

Frontiers in Oncology

doi 10.3389/fonc.2021.719564

27,695 views
109 citations

Original Research

Published on 02 Aug 2021

Radiomics-Based Texture Analysis of 68Ga-DOTATATE Positron Emission Tomography and Computed Tomography Images as a Prognostic Biomarker in Adults With Neuroendocrine Cancers Treated With 177Lu-DOTATATE

in Cancer Imaging and Image-directed Interventions

Charlotte Atkinson
Balaji Ganeshan
Raymond Endozo
Simon Wan
Matthew D. Aldridge
Ashley M. Groves
Jamshed B. Bomanji
Mark N. Gaze

Frontiers in Oncology

doi 10.3389/fonc.2021.686235

4,842 views
36 citations

Articles

Radiomic Analysis of Tumour Heterogeneity Using MRI in Head and Neck Cancer Following Chemoradiotherapy: A Feasibility Study

Advances in hepatocellular carcinoma drug resistance models

The mechanism of action, clinical significance, and research progress of tumor antigen-specific T cells in the treatment of HCC

Patient-derived cancer models: Valuable platforms for anticancer drug testing

Clinical Applications of Circulating Tumour Cells and Circulating Tumour DNA in Non-Small Cell Lung Cancer—An Update

Radioresistance and brain metastases: a review of the literature and applied perspective

Therapies targeting triple-negative breast cancer: a perspective on anti-FGFR

Osteosarcoma 3D patient derived cultures to test genome-informed personalized treatment options; a feasibility study

Expression of the apelin receptor, a novel potential therapeutic target, and its endogenous ligands in diverse stem cell populations in human glioblastoma

MRI-based radiomics for noninvasive prediction of T790M resistance mutation in lung cancer spinal metastases: an exploratory study

Novel Ex Vivo Models of Epithelial Ovarian Cancer: The Future of Biomarker and Therapeutic Research

Single-Cell RNA Sequencing in Multiple Pathologic Types of Renal Cell Carcinoma Revealed Novel Potential Tumor-Specific Markers

Radiomics-Based Texture Analysis of 68Ga-DOTATATE Positron Emission Tomography and Computed Tomography Images as a Prognostic Biomarker in Adults With Neuroendocrine Cancers Treated With 177Lu-DOTATATE