Ulcer Index | List of Frontiers open access articles

Original Research

Published on 08 Jan 2024

Mechanism of Wuzhuyu decoction on alcohol-induced gastric ulcers using integrated network analysis and metabolomics

in Ethnopharmacology

Xin Wang
Lisheng Chen
Lei Chang
Yong He
Tingting He
Ruilin Wang
Shizhang Wei
Manyi Jing
Xuelin Zhou
Haotian Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1308995

4,824 views
11 citations

Systematic Review

Published on 20 Mar 2026

Preclinical evidence of the therapeutic effect of Moringa oleifera in peptic ulcer disease: a systematic review and meta-analysis

in Ethnopharmacology

Saheed Olatunbosun Akiode
Adeoti Gbemisola Adeniran
Oyedayo Phillips Akano
Ayokunmi Stephen Olusa
Oghale Oghenefego Ovuakporie-Uvo
Oluchukwu Perpetual Okeke
Olunike Rebecca Abodunrin
Folahanmi Tomiwa Akinsolu
Uwaisu Iliyasu
Olajide Odunayo Sobande

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1689789

1,136 views

Original Research

Published on 26 Nov 2020

Rutaecarpine Ameliorates Ethanol-Induced Gastric Mucosal Injury in Mice by Modulating Genes Related to Inflammation, Oxidative Stress and Apoptosis

in Gastrointestinal and Hepatic Pharmacology

Sichen Ren
Ying Wei
Ruilin Wang
Shizhang Wei
Jianxia Wen
Tao Yang
Xing Chen
Shihua Wu
Manyi Jing
Haotian Li

Frontiers in Pharmacology

doi 10.3389/fphar.2020.600295

8,424 views
64 citations

Original Research

Published on 25 Feb 2022

Increasing Aspartoacylase in the Central Amygdala: The Common Mechanism of Gastroprotective Effects of Monoamine-Based Antidepressants Against Stress

in Neuropharmacology

Kaiyun Yao
Linyu Cao
Hongwan Ding
Yinge Gao
Tiegang Li
Guibin Wang
Jianjun Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.823291

3,443 views
4 citations

Original Research

Published on 09 Feb 2023

Amoxicillin-docosahexaenoic acid encapsulated chitosan-alginate nanoparticles as a delivery system with enhanced biocidal activities against Helicobacter pylori and improved ulcer healing

in Infectious Agents and Disease

Saeed Khoshnood
Babak Negahdari
Vahab Hassan Kaviar
Nourkhoda Sadeghifard
Mohd Azmuddin Abdullah
Mohamed El-Shazly
Mohammad Hossein Haddadi

Frontiers in Microbiology

doi 10.3389/fmicb.2023.1083330

5,284 views
21 citations

Original Research

Published on 10 Aug 2023

An integrated network analysis, RNA-seq and in vivo validation approaches to explore the protective mechanism of Mongolian medicine formulae Ruda-6 against indomethacin-induced gastric ulcer in rats

in Ethnopharmacology

Lan Feng
Lisha A.
Terigele Bao
Xiyele Mu
Na Ta
Qiang Duan
La Ta
Yongsheng Chen
Laxinamujila Bai
Minghai Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1181133

6,857 views
5 citations

Original Research

Published on 15 Feb 2024

Utilization of nanotechnology and experimental design in the development and optimization of a posaconazole‒calendula oil nanoemulgel for the treatment of mouth disorders

in Experimental Pharmacology and Drug Discovery

Mohammed Alissa
Ahmed Hjazi
Ghadah S. Abusalim
Ghfren S. Aloraini
Suad A. Alghamdi
Nahed S. Alharthi
Waleed Y. Rizg
Khaled M. Hosny
Nada Binmadi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1347551

4,839 views
7 citations

Original Research

Published on 25 Feb 2021

Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role

in Gastrointestinal and Hepatic Pharmacology

Mohammad Raish
Mudassar Shahid
Yousef A. Bin Jardan
Mushtaq Ahmad Ansari
Khalid M. Alkharfy
Abdul Ahad
Ibrahim Abdelsalam Abdelrahman
Ajaz Ahmad
Fahad I. Al-Jenoobi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.622815

19,319 views
125 citations

Original Research

Published on 07 Nov 2025

Research on the effect of Rosa roxburghii root in alleviating spleen and stomach damp–heat gastric ulcer by regulating the imbalance of oral–gut axis microbiota

in Microorganisms in Vertebrate Digestive Systems

Jiangsong Cao
Ziyu Zhang
Xiongwei Liu
Ying Zhou
Jiaxin Li
Xinyue Wang
Chang Liu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1701829

2,682 views

Original Research

Published on 12 Sep 2019

Influence of the Novel Histamine H3 Receptor Antagonist/Inverse Agonist M39 on Gastroprotection and PGE2 Production Induced by (R)-Alpha-Methylhistamine in C57BL/6 Mice

in Gastrointestinal and Hepatic Pharmacology

Salim M. A. Bastaki
Naheed Amir
Małgorzata Więcek
Katarzyna Kieć-Kononowicz
Bassem Sadek

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00966

4,473 views
3 citations

Articles

Mechanism of Wuzhuyu decoction on alcohol-induced gastric ulcers using integrated network analysis and metabolomics

Preclinical evidence of the therapeutic effect of Moringa oleifera in peptic ulcer disease: a systematic review and meta-analysis

Rutaecarpine Ameliorates Ethanol-Induced Gastric Mucosal Injury in Mice by Modulating Genes Related to Inflammation, Oxidative Stress and Apoptosis

Increasing Aspartoacylase in the Central Amygdala: The Common Mechanism of Gastroprotective Effects of Monoamine-Based Antidepressants Against Stress

Amoxicillin-docosahexaenoic acid encapsulated chitosan-alginate nanoparticles as a delivery system with enhanced biocidal activities against Helicobacter pylori and improved ulcer healing

An integrated network analysis, RNA-seq and in vivo validation approaches to explore the protective mechanism of Mongolian medicine formulae Ruda-6 against indomethacin-induced gastric ulcer in rats

Utilization of nanotechnology and experimental design in the development and optimization of a posaconazole‒calendula oil nanoemulgel for the treatment of mouth disorders

Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role

Research on the effect of Rosa roxburghii root in alleviating spleen and stomach damp–heat gastric ulcer by regulating the imbalance of oral–gut axis microbiota

Influence of the Novel Histamine H3 Receptor Antagonist/Inverse Agonist M39 on Gastroprotection and PGE2 Production Induced by (R)-Alpha-Methylhistamine in C57BL/6 Mice