Warhead | List of Frontiers open access articles

Original Research

Published on 27 Apr 2017

Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome

in Antimicrobials, Resistance and Chemotherapy

Wilfried Moreira
Sridhar Santhanakrishnan
Brian W. Dymock
Thomas Dick

Frontiers in Microbiology

doi 10.3389/fmicb.2017.00746

5,540 views
34 citations

Mini Review

Published on 20 Jul 2022

Advances in UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) Covalent Inhibition

in Biological Modeling and Simulation

Maycon Vinicius Damasceno de Oliveira
Renan Machado Furtado
Kauê S. da Costa
Serhii Vakal
Anderson H. Lima

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.889825

9,252 views
14 citations

Original Research

Published on 07 Sep 2022

Covalent fragment inhibits intramembrane proteolysis

in Molecular Recognition

Angela Eden
Jing Zhao
Yuanyuan Xiao
James Gibson
Chunyu Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.958399

3,979 views
3 citations

Original Research

Published on 26 Mar 2019

Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines

in Cancer Molecular Targets and Therapeutics

Claudia Fumarola
Nicole Bozza
Riccardo Castelli
Francesca Ferlenghi
Giuseppe Marseglia
Alessio Lodola
Mara Bonelli
Silvia La Monica
Daniele Cretella
Roberta Alfieri

Frontiers in Oncology

doi 10.3389/fonc.2019.00179

15,112 views
45 citations

Original Research

Published on 20 Mar 2023

Study on the ground impact vibration intensity model of high energy warhead explosion

in Interdisciplinary Physics

Liangquan Wang
Deren Kong
Fei Shang

Frontiers in Physics

doi 10.3389/fphy.2023.1114871

2,904 views
3 citations

Original Research

Published on 29 Aug 2023

Research on explosive damage effects of tungsten fiber-reinforced Zr-based bulk metallic glass matrix composite shell

in Mechanics of Materials

Bingnan Xing
Chengxin Du
Zhonghua Du
Huameng Fu
Zhengwang Zhu
Feng Zhou

Frontiers in Materials

doi 10.3389/fmats.2023.1241011

3,238 views
2 citations

Mini Review

Published on 10 Mar 2026

Sulfur-and selenium-targeting warheads: reaction-based design of electrophilic warheads for selective inhibition of enzyme

in Chemical Biology

Neha Jain
Michio Iwaoka

Frontiers in Chemistry

doi 10.3389/fchem.2026.1768658

518 views

Original Research

Published on 16 Feb 2022

Equipping Coiled-Coil Peptide Dimers With Furan Warheads Reveals Novel Cross-Link Partners

in Chemical Biology

Laia Miret-Casals
Sander Van De Putte
Dorien Aerssens
Julien Diharce
Pascal Bonnet
Annemieke Madder

Frontiers in Chemistry

doi 10.3389/fchem.2021.799706

5,791 views
7 citations

Original Research

Published on 09 Jul 2024

Capturing Legionella pneumophila effector enzymes using a ubiquitin derived photo-activatable probe

in Protein Biochemistry for Basic and Applied Sciences

Max S. Kloet
Gerbrand J. van der Heden van Noort

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1422034

2,562 views
2 citations

Original Research

Published on 03 Mar 2023

Integration of molecular modelling and in vitro studies to inhibit LexA proteolysis

in Clinical and Diagnostic Microbiology and Immunology

Zachariah P. Schuurs
John P. McDonald
Laura V. Croft
Derek J. Richard
Roger Woodgate
Neha S. Gandhi

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1051602

3,790 views
5 citations

Original Research

Published on 31 Oct 2024

Evaluation of an anthropometric head surrogate exposed to chisel-nosed fragment simulating projectile impact

in Solid and Structural Mechanics

Punit Kumar Pandey
S. G. Ganpule

Frontiers in Mechanical Engineering

doi 10.3389/fmech.2024.1446479

2,132 views
1 citation

Original Research

Published on 06 Jan 2026

Activity-based chemoproteomic profiling reveals the active kinome of Leishmania

in Pharmacology of Infectious Diseases

Exequiel O. J. Porta
Karunakaran Kalesh
Patrick G. Steel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1687590

1,226 views

Articles

Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome

Advances in UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) Covalent Inhibition

Covalent fragment inhibits intramembrane proteolysis

Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines

Study on the ground impact vibration intensity model of high energy warhead explosion

Research on explosive damage effects of tungsten fiber-reinforced Zr-based bulk metallic glass matrix composite shell

Sulfur-and selenium-targeting warheads: reaction-based design of electrophilic warheads for selective inhibition of enzyme

Equipping Coiled-Coil Peptide Dimers With Furan Warheads Reveals Novel Cross-Link Partners

Capturing Legionella pneumophila effector enzymes using a ubiquitin derived photo-activatable probe

Integration of molecular modelling and in vitro studies to inhibit LexA proteolysis

Evaluation of an anthropometric head surrogate exposed to chisel-nosed fragment simulating projectile impact

Activity-based chemoproteomic profiling reveals the active kinome of Leishmania