Cellular and Developmental Biology| Frontiers Articles

Cell and Developmental Biology: read our trending articles

Cell and developmental biology research is advancing our understanding of complex biological processes and therapeutic approaches. From skeletal muscle regeneration and targeting cell death pathways in cancer to the potential of exosomes and CAR macrophages in treatment, these studies highlight recent developments.

Explore these trending articles in Frontiers in Cell and Developmental Biology and apply the latest findings to your research or clinical practice.

Human anatomy detail of shoulder. Muscle, arteries on plain studio background. Professional lighting.

REVIEW article

Published on 10 Jul 2024

We need to talk—how muscle stem cells communicate

Skeletal muscle stem cells regenerate muscle by interacting with their niche through various signaling pathways to maintain quiescence, activation, and self-renewal – a process affected by aging and disease.

Scientist preparing samples for flow cytometric analysis in the laboratory. Cancer diagnosis

REVIEW article

Published on 15 Nov 2024

Targeting regulated cell death pathways in cancers for effective treatment: a comprehensive review

This review suggests that targeting dysregulated cell death pathways, like apoptosis and ferroptosis, can disrupt tumor survival mechanisms in cancer. This approach aims to create effective personalized therapies by addressing these critical processes.

REVIEW article

Published on 10 Jul 2024

We need to talk—how muscle stem cells communicate

REVIEW article

Published on 15 Nov 2024

Targeting regulated cell death pathways in cancers for effective treatment: a comprehensive review

Hearing Aid And Audiology. Handicap And Disability Aid

REVIEW article

Published on 20 Feb 2023

Mitochondrial dysfunction in hearing loss: Oxidative stress, autophagy and NLRP3 inflammasome

Mitochondrial dysfunction, caused by reactive oxygen species and NLRP3 inflammasome activation, contributes to sensorineural deafness, while boosting autophagy may protect auditory cells by reducing oxidative stress and clearing damaged mitochondria.

Senior woman sitting in hospital room after chemotherapy.

REVIEW article

Published on 13 Feb 2024

Exosomes: a promising avenue for cancer diagnosis beyond treatment

Exosomes, due to their tumor-specific signatures, offer promise for early cancer diagnosis and monitoring, while challenges in standardization limit their use in targeted therapies.

REVIEW article

Published on 20 Feb 2023

Mitochondrial dysfunction in hearing loss: Oxidative stress, autophagy and NLRP3 inflammasome

REVIEW article

Published on 13 Feb 2024

Exosomes: a promising avenue for cancer diagnosis beyond treatment

Exosomes, due to their tumor-specific signatures, offer promise for early cancer diagnosis and monitoring, while challenges in standardization limit their use in targeted therapies.

Closeup of hand glove of scientist put slide glass on the inverted microscope for looking culture cells for bioassay in the laboratory.Research for pharmaceutical and biotechnology development.

REVIEW article

Published on 23 Oct 2024

Mechanosensory entities and functionality of endothelial cells

This review discusses endothelial mechanosensitivity, its dysregulation in diseases, and interactions with vascular smooth muscle cells, as well as future research directions needed to address current knowledge gaps.

PERSPECTIVE article

Published on 15 Aug 2024

Regulation of biological processes by ubiquitin ligases: a focus on the Pagano Lab’s contribution

Bone marrow mesenchymal stem cells can treat osteoarthritis by using paracrine signals to regulate immune responses, suppress inflammation, and support tissue repair, highlighting their potential as a novel, cell-free therapeutic approach.

REVIEW article

Published on 23 Oct 2024

Mechanosensory entities and functionality of endothelial cells

PERSPECTIVE article

Published on 15 Aug 2024

Regulation of biological processes by ubiquitin ligases: a focus on the Pagano Lab’s contribution

antibodies contribute to brain pathology associated with autoimmune diseases such as systemic lupus erythematosus and neuromyelitis optica 3d rendering

ORIGINAL RESEARCH article

Published on 17 Dec 2024

Transcriptomics as a predictor of biopharmaceutically favourable glycan profiles

Transcriptomics can predict glycosylation profiles for monoclonal antibodies by identifying genetic markers such as Alg5, though enzyme localization and competition within cells are also critical factors.

Young serious African man with microscope sitting by workplace in front of computer monitors and colleague on background

REVIEW article

Published on 26 Jul 2024

Immunoregulatory paracrine effect of mesenchymal stem cells and mechanism in the treatment of osteoarthritis

Bone marrow mesenchymal stem cells (BMSCs) can treat osteoarthritis through paracrine signaling, which regulates immune responses and reduces inflammation, with BMSC-derived exosomes showing potential as a cell-free therapy option.

ORIGINAL RESEARCH article

Published on 17 Dec 2024

Transcriptomics as a predictor of biopharmaceutically favourable glycan profiles

REVIEW article

Published on 26 Jul 2024

Immunoregulatory paracrine effect of mesenchymal stem cells and mechanism in the treatment of osteoarthritis

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