Pharmacology

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Pharmacology

Pharmacology is a branch of biomedical science that focuses on the study of drugs and their effects on living organisms. Our Research Topics explore how drugs impact the body at the molecular, cellular, and physiological levels and identifies how these effects can be harnessed for therapeutic purposes in healthcare.

The following Research Topics are led by experts in their field and contribute to the scientific understanding of pharmacology. These Research topics are published in the peer-reviewed journal Frontiers in Pharmacology, as open access articles.

Research Topics

Frontiers' Research Topics are peer-reviewed article collections around cutting-edge research themes.
Learn more about how Research topics work.

Women work in the lab. Conducts experiments on vaccines.

Combination Therapies in Cancer Treatment: Enhancing Efficacy and Reducing Resistance

Combination therapies represent a promising frontier in cancer treatment, addressing the critical need to enhance efficacy while minimizing resistance.

Dopaminergic neuron, computer reconstruction. Degeneration of this brain cells are responsible for development of Parkinson's disease, 3D illustration

Targeted Drug Delivery and Mode of Action of Small Molecules in Neuroinflammation

Neuroinflammation drives the progression of neurodegenerative disorders like Alzheimer's, Parkinson's, and multiple sclerosis.

3D Rendering Liver Lobule Cells

Liver Diseases and Their Impact on Drug Metabolism

The metabolism and detoxification of xenobiotic compounds, including drugs, takes place mainly in the liver and, therefore, liver diseases may negatively affect these processes.

Doctor prepares to conduct an ultrasound examination of the heart and abdominal organs of a newborn boy using modern medical equipment in a clinic. Pediatrics and child development monitoring.

Exploring Adverse Drug Reactions, Medication Adherence, and Forensic Markers in Pediatrics and Obstetrics

Adverse drug reactions (ADRs) and medication adherence are critical aspects of healthcare, particularly within pediatric and obstetric fields.

3d rendered medically accurate illustration of a womans large intestine

New Insights into the Management of Chronic Idiopathic Constipation: From Physiopathology to Novel Therapeutic Strategies

Chronic Idiopathic Constipation (CIC) encompasses disorders of gut-brain interaction (DGBI) as defined by the Rome IV criteria, all characterized by symptoms of constipation.

Nurse caring about the little patient

Innovative Approaches for Wound Treatment

Wound healing is vital for restoring tissue integrity but is often complicated by chronic conditions and infections. Traditional treatment methods frequently fail to provide effective outcomes.

Close up 60s old woman pours out from bottle pills time to take medicaments, cure for memory loss, high blood pressure or cholesterol level remedy pain killer drugs, senile diseases treatments concept

Challenges and Opportunities with the Rollout of New Alzheimer’s Disease Drugs: A Focus on Non-Alzheimer's Dementia

This Research Topic will showcase the better biomarkers and therapies impacted by the recent developments of AD drugs and the practical implications of this breakthrough

Peaceful loving young African mother sitting on bed and leaning on headboard while feeding baby with breast

World Breastfeeding Week 2024: An Obstetric and Pediatric Pharmacology Perspective

World Breastfeeding Week (WBW) is celebrated annually in the first week of August, organized by the World Alliance for Breastfeeding Action (WABA),

Bioinformatics. Technicians checking out an image of cromosomeson the screen

Editor's Feature: Negative Findings in Pharmacogenetics and Pharmacogenomics Volume II

In the field of Pharmacogenetics and Pharmacogenomics, there is a significant bias towards publishing positive results over negative or null findings, despite the latter often being well-supported by sound biological reasoning

_3d render of colorful rings. Big Data. Glowing abstract geometry composition with reflections. Depth of field effect.

State-of-the-art hypothesis-driven systems pharmacology and artificial intelligence approaches to decipher disease complexity

Most human diseases are inherently complex and rely on intricate gene-gene interactions to exert their pathological outcomes.

A crowd of Mediterranean fish in the crystal clear waters of Villasimius, Sardinia, Mediterranean. Underwater photography

The Multiple Applications of Marine-Derived Bioactives

Marine biotechnology is a rapidly evolving field that focuses on the exploration and utilization of marine-derived bioactives, which are secondary metabolites with diverse biological activities such as antibacterial,

Cannabis plants growing indoors with health issues like thrips attack or lack of micro nutrients problems reflected in leaf spots.

Cannabis and Cannabinoids for Pain Treatment: Clinical and Non-Clinical Advances on Mechanisms and Applications

We encourage research on pharmacological interventions to understand mechanisms and treat pain disorders.

Close-up Shot of the Industrial Manufacturing Medical Test Tubes, Process of Sterilising and Filling Items. Sterile High Precision Factory Machinery Producing Items for Medical Use. Abstract Concept.

Intelligent Computing for Integrating Multi-Omics Data in Disease Diagnosis and Drug Development

In the modern landscape of health science, the emergence of complex diseases presents a formidable challenge, demanding cutting-edge computational methods to elucidate

Female genetics worker placing the strips with DNA into the PCR thermal cycler or amplifier for PCR diagnostics

Genetic and Pharmacological Frontiers in Cancer Treatment

Cancer genetics stands at the forefront of oncology research, elucidating the molecular dynamics behind cancer development and progression.

Image of woman with mental disorder holding broken mirror

World Schizophrenia Awareness Day: Raising Awareness and Advancing Pharmacological Strategies in Schizophrenia

World Schizophrenia Awareness Day, commemorated every May 24, underscores the global impact of this mental illness, affecting over 20 million individuals worldwide.

3d abstract red blood cells illustration, scientific or medical or microbiological background

Nutrition as a Pharmacological Approach to Metabolic Disorders and Ageing

The field of nutrition pharmacology is emerging as a promising area of research, focusing on the role of food as a modulator of cellular signaling and its impact on health.

3D illustration of a cluster of Fat cells.

Targeting Adipose Tissue for the Treatment of Metabolic Alterations

Adipose tissue is a dynamic organ that plays a pivotal role in the regulation of energy storage and thermogenesis, influencing many physiological processes such as glucose and lipid metabolism,

Skin cancer cells, 3D illustration

Advanced Therapeutic Strategies in Digestive and Circulatory Health: Nanomedicine and Beyond

In an era marked by rapid advancements in medical technology, the digestive and circulatory systems—key components critical to human health—

A scientist in sterile coverall gown using alcohol 70% and cleanroom wipes for cleaning Biological safety cabinet(BSC.) in laboratory, before and after using bsc. ,decontamination,Cleanroom facility.

Advances in Biomarkers and Drug Targets: Harnessing Traditional and AI Approaches for Novel Therapeutic Mechanisms

The discovery of new biomarkers, drug targets, and therapeutic mechanisms is pivotal for the development of effective treatments across a spectrum of diseases.

Synapse and Neuron cells sending electrical chemical signals . 3D illustration

The Interplay Between GABA and Glutamate in Systems Physiology and Pathophysiology

Gamma-Aminobutyric Acid (GABA) and glutamate are the principal neurotransmitters in the central nervous system, playing crucial roles in keeping the balance between excitatory and inhibitory

Women work in the lab. Conducts experiments on vaccines.

Combination Therapies in Cancer Treatment: Enhancing Efficacy and Reducing Resistance

Combination therapies represent a promising frontier in cancer treatment, addressing the critical need to enhance efficacy while minimizing resistance.

Dopaminergic neuron, computer reconstruction. Degeneration of this brain cells are responsible for development of Parkinson's disease, 3D illustration

Targeted Drug Delivery and Mode of Action of Small Molecules in Neuroinflammation

Neuroinflammation drives the progression of neurodegenerative disorders like Alzheimer's, Parkinson's, and multiple sclerosis.

3D Rendering Liver Lobule Cells

Liver Diseases and Their Impact on Drug Metabolism

The metabolism and detoxification of xenobiotic compounds, including drugs, takes place mainly in the liver and, therefore, liver diseases may negatively affect these processes.

Doctor prepares to conduct an ultrasound examination of the heart and abdominal organs of a newborn boy using modern medical equipment in a clinic. Pediatrics and child development monitoring.

Exploring Adverse Drug Reactions, Medication Adherence, and Forensic Markers in Pediatrics and Obstetrics

Adverse drug reactions (ADRs) and medication adherence are critical aspects of healthcare, particularly within pediatric and obstetric fields.

3d rendered medically accurate illustration of a womans large intestine

New Insights into the Management of Chronic Idiopathic Constipation: From Physiopathology to Novel Therapeutic Strategies

Chronic Idiopathic Constipation (CIC) encompasses disorders of gut-brain interaction (DGBI) as defined by the Rome IV criteria, all characterized by symptoms of constipation.

Nurse caring about the little patient

Innovative Approaches for Wound Treatment

Wound healing is vital for restoring tissue integrity but is often complicated by chronic conditions and infections. Traditional treatment methods frequently fail to provide effective outcomes.

Close up 60s old woman pours out from bottle pills time to take medicaments, cure for memory loss, high blood pressure or cholesterol level remedy pain killer drugs, senile diseases treatments concept

Challenges and Opportunities with the Rollout of New Alzheimer’s Disease Drugs: A Focus on Non-Alzheimer's Dementia

This Research Topic will showcase the better biomarkers and therapies impacted by the recent developments of AD drugs and the practical implications of this breakthrough

Peaceful loving young African mother sitting on bed and leaning on headboard while feeding baby with breast

World Breastfeeding Week 2024: An Obstetric and Pediatric Pharmacology Perspective

World Breastfeeding Week (WBW) is celebrated annually in the first week of August, organized by the World Alliance for Breastfeeding Action (WABA),

Bioinformatics. Technicians checking out an image of cromosomeson the screen

Editor's Feature: Negative Findings in Pharmacogenetics and Pharmacogenomics Volume II

In the field of Pharmacogenetics and Pharmacogenomics, there is a significant bias towards publishing positive results over negative or null findings, despite the latter often being well-supported by sound biological reasoning

_3d render of colorful rings. Big Data. Glowing abstract geometry composition with reflections. Depth of field effect.

State-of-the-art hypothesis-driven systems pharmacology and artificial intelligence approaches to decipher disease complexity

Most human diseases are inherently complex and rely on intricate gene-gene interactions to exert their pathological outcomes.

A crowd of Mediterranean fish in the crystal clear waters of Villasimius, Sardinia, Mediterranean. Underwater photography

The Multiple Applications of Marine-Derived Bioactives

Marine biotechnology is a rapidly evolving field that focuses on the exploration and utilization of marine-derived bioactives, which are secondary metabolites with diverse biological activities such as antibacterial,

Cannabis plants growing indoors with health issues like thrips attack or lack of micro nutrients problems reflected in leaf spots.

Cannabis and Cannabinoids for Pain Treatment: Clinical and Non-Clinical Advances on Mechanisms and Applications

We encourage research on pharmacological interventions to understand mechanisms and treat pain disorders.

Close-up Shot of the Industrial Manufacturing Medical Test Tubes, Process of Sterilising and Filling Items. Sterile High Precision Factory Machinery Producing Items for Medical Use. Abstract Concept.

Intelligent Computing for Integrating Multi-Omics Data in Disease Diagnosis and Drug Development

In the modern landscape of health science, the emergence of complex diseases presents a formidable challenge, demanding cutting-edge computational methods to elucidate

Female genetics worker placing the strips with DNA into the PCR thermal cycler or amplifier for PCR diagnostics

Genetic and Pharmacological Frontiers in Cancer Treatment

Cancer genetics stands at the forefront of oncology research, elucidating the molecular dynamics behind cancer development and progression.

Image of woman with mental disorder holding broken mirror

World Schizophrenia Awareness Day: Raising Awareness and Advancing Pharmacological Strategies in Schizophrenia

World Schizophrenia Awareness Day, commemorated every May 24, underscores the global impact of this mental illness, affecting over 20 million individuals worldwide.

3d abstract red blood cells illustration, scientific or medical or microbiological background

Nutrition as a Pharmacological Approach to Metabolic Disorders and Ageing

The field of nutrition pharmacology is emerging as a promising area of research, focusing on the role of food as a modulator of cellular signaling and its impact on health.

3D illustration of a cluster of Fat cells.

Targeting Adipose Tissue for the Treatment of Metabolic Alterations

Adipose tissue is a dynamic organ that plays a pivotal role in the regulation of energy storage and thermogenesis, influencing many physiological processes such as glucose and lipid metabolism,

Skin cancer cells, 3D illustration

Advanced Therapeutic Strategies in Digestive and Circulatory Health: Nanomedicine and Beyond

In an era marked by rapid advancements in medical technology, the digestive and circulatory systems—key components critical to human health—

A scientist in sterile coverall gown using alcohol 70% and cleanroom wipes for cleaning Biological safety cabinet(BSC.) in laboratory, before and after using bsc. ,decontamination,Cleanroom facility.

Advances in Biomarkers and Drug Targets: Harnessing Traditional and AI Approaches for Novel Therapeutic Mechanisms

The discovery of new biomarkers, drug targets, and therapeutic mechanisms is pivotal for the development of effective treatments across a spectrum of diseases.

Synapse and Neuron cells sending electrical chemical signals . 3D illustration

The Interplay Between GABA and Glutamate in Systems Physiology and Pathophysiology

Gamma-Aminobutyric Acid (GABA) and glutamate are the principal neurotransmitters in the central nervous system, playing crucial roles in keeping the balance between excitatory and inhibitory