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Exercise as a Countermeasure to Human Aging

Original Research ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Physiol. | doi: 10.3389/fphys.2019.00484

Independent and Combined Effects of antioxidant supplementation and Circuit Resistance Training on selected Adipokines in Postmenopausal Women

  • 1University of Mazandaran, Iran
  • 2Qatar University, Qatar
  • 3Sport Science Program, College of Arts and Sciences, Qatar University., Qatar
  • 4Islamic Azad University System, Iran
  • 5Louisiana State University, United States
  • 6University of North Carolina at Chapel Hill, United States
  • 7University of Birjand, Iran
  • 8Medical University of Ilam, Iran
  • 9Higher Institute of Sport and Physical Education of Ksar Saïd, University of Manouba, Tunisia
  • 10University of Rennes 2 – Upper Brittany, France

We examined the effects of the independent and combined effects of Zataria multiflora supplementation and circuit resistance training (CRT) on selected adipokines among postmenopausal women.
Forty-eight postmenopausal women were divided into 4 groups: Exercise (EG, n =12), Zataria multiflora (ZMG, n =12), exercise and Zataria multiflora (ZMEG, n =12), and control (CG, n=12). Participants in experimental groups either performed CRT (3 sessions per week with intensity at 55% of one-repetition maximum) or supplemented with Zataria Multiflora (500mg every day after breakfast with 100 ml of water), or their combination, for 8 weeks. Blood samples were collected at pre- and post-intervention for measuring selected adipokines, including visfatin, omentin-1, vaspin, FGF-21, adiponectin, leptin, and ghrelin.
Our findings demonstrated that visfatin, vaspin, and leptin levels significantly decreased over the intervention period (all P < .05), with these values were lower in EG and ZMEG in comparison to CG at post-intervention (all P < .05). Visfatin and vaspin levels were also lower in ZMEG in comparison to EG at post-intervention (both P < .05). In contrast, omentin-1, gherlin, adiponectin, and FGF21 significantly increased in EG and EMG (all P < .05) after CRT.
These finding suggest that Zataria Multiflora supplementation by itself has little effect on measured adipokines, however, its combination with CRT produced noticeable effects on circulating levels of these adipokines, even more than CRT alone. Consequently, combination of CRT and Zataria Multiflora supplementation may represent a potentially beneficial non-pharmacologic intervention on some selected adipokines in postmenopausal women.

Keywords: postmenopausal women, Zataria multiflora, Adipokine, visfatin, Vaspin, Leptin, Inflammation, metabolic syndrome

Received: 19 Dec 2018; Accepted: 08 Apr 2019.

Edited by:

Martin Burtscher, University of Innsbruck, Austria

Reviewed by:

Josefa Leon, Fundación para la Investigación Biosanitaria de Andalucía Oriental (FIBAO), Spain
Linda K. Rausch, Hermann Buhl Institute for Hypoxia and Sleep Medicine, Germany  

Copyright: © 2019 Saeidi, Jabbour, Ahmadian, Abbadi-Daloii, Malekian, Hackney, Saedmocheshi, Bassati, Ben Abderrahman and ZOUHAL. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dr. Georges Jabbour, Qatar University, Doha, Qatar, georgesjabbour1980@hotmail.com