Frontiers in Drug Delivery | CNS Drug Delivery

Review

Published on 12 Mar 2024

Receptor-mediated transcytosis for brain delivery of therapeutics: receptor classes and criteria

in CNS Drug Delivery

Arsalan S. Haqqani
Kasandra Bélanger
Danica B. Stanimirovic

Frontiers in Drug Delivery

doi 10.3389/fddev.2024.1360302

20,841 views
36 citations

Review

Published on 11 Aug 2023

Transnasal-brain delivery of nanomedicines for neurodegenerative diseases

in CNS Drug Delivery

Xu Zhang
Maohua Wang
Zhixian Liu
Ying Wang
Li Chen
Jiaqi Guo
Wentao Zhang
Yao Zhang
Chenjie Yu
Tongwu Bie

Frontiers in Drug Delivery

doi 10.3389/fddev.2023.1247162

6,118 views
4 citations

Review

Published on 10 Jul 2023

Receptor-mediated drug delivery of bispecific therapeutic antibodies through the blood-brain barrier

in CNS Drug Delivery

William M. Pardridge

Frontiers in Drug Delivery

doi 10.3389/fddev.2023.1227816

12,561 views
25 citations

Brief Research Report

Published on 03 Jul 2023

Transferrin receptor-targeting property of pabinafusp alfa facilitates its uptake by various types of human brain-derived cells in vitro

in CNS Drug Delivery

Tomoki Fukatsu
Hanae Morio
Tomomi Furihata
Hiroyuki Sonoda

Frontiers in Drug Delivery

doi 10.3389/fddev.2023.1082672

3,304 views

Original Research

Published on 23 May 2023

Identification of transport systems involved in eflornithine delivery across the blood-brain barrier

in CNS Drug Delivery

Christopher P. Watson
Gayathri Nair Sekhar
Sarah A. Thomas

Frontiers in Drug Delivery

doi 10.3389/fddev.2023.1113493

3,175 views
6 citations

Brief Research Report

Published on 29 Mar 2023

Reduction in cardiolipin reduces expression of creatine transporter-1 and creatine transport in growing hCMEC/D3 human brain microvessel endothelial cells

in CNS Drug Delivery

Donald W. Miller
Grant M. Hatch

Frontiers in Drug Delivery

doi 10.3389/fddev.2023.1158369

2,157 views

Brief Research Report

Published on 05 Jan 2023

SorLA in astrocytes regulates blood-brain barrier integrity

in CNS Drug Delivery

Andrea E. Toth
Adrian Klepe
Dora V. Lipka
Charlotte Goldeman
Birger Brodin
Morten S. Nielsen

Frontiers in Drug Delivery

doi 10.3389/fddev.2022.1082689

4,324 views
6 citations

Mini Review

Published on 14 Dec 2022

Neurotropism and blood-brain barrier involvement in COVID-19

in CNS Drug Delivery

Takashi Fujimoto
Michelle A. Erickson
William A. Banks

Frontiers in Drug Delivery

doi 10.3389/fddev.2022.1073815

2,550 views
4 citations

Original Research

Published on 24 Nov 2022

Endocytosis of insulin at the blood-brain barrier

in CNS Drug Delivery

Sarah Pemberton
Demi C. Galindo
Michael W. Schwartz
William A. Banks
Elizabeth M. Rhea

Frontiers in Drug Delivery

doi 10.3389/fddev.2022.1062366

4,972 views
11 citations

Review

Published on 01 Nov 2022

Role of microRNAs in the regulation of blood-brain barrier function in ischemic stroke and under hypoxic conditions in vitro

in CNS Drug Delivery

Aili Sun
Kinga G. Blecharz-Lang
Andrzej Małecki
Patrick Meybohm
Marta M. Nowacka-Chmielewska
Malgorzata Burek

Frontiers in Drug Delivery

doi 10.3389/fddev.2022.1027098

3,672 views
5 citations

Mini Review

Published on 25 Jul 2022

The Blood-Brain Barrier in Space: Implications for Space Travelers and for Human Health on Earth

in CNS Drug Delivery

Shimon Amselem
Sara Eyal

Frontiers in Drug Delivery

doi 10.3389/fddev.2022.931221

5,050 views
4 citations

Original Research

Published on 22 Jul 2022

Quantitative Comparison of Breast Cancer Resistance Protein (BCRP/ABCG2) Expression and Function Between Maternal Blood-Brain Barrier and Placental Barrier in Mice at Different Gestational Ages

in CNS Drug Delivery

Arimi Fujita
Saki Noguchi
Rika Hamada
Tsutomu Shimada
Satomi Katakura
Tetsuo Maruyama
Yoshimichi Sai
Tomohiro Nishimura
Masatoshi Tomi

Frontiers in Drug Delivery

doi 10.3389/fddev.2022.932576

2,845 views
1 citation

Mini Review

Published on 12 Jul 2022

The Roads We Take: Cellular Targets and Pathways Leading Biologics Across the Blood–Brain Barrier

in CNS Drug Delivery

Habib Baghirov

Frontiers in Drug Delivery

doi 10.3389/fddev.2022.946045

4,766 views
1 citation

Review

Published on 26 Apr 2022

Effects of Nicotine Exposure From Tobacco Products and Electronic Cigarettes on the Pathogenesis of Neurological Diseases: Impact on CNS Drug Delivery

in CNS Drug Delivery

Sejal Sharma
Sabrina Rahman Archie
Vrajesh Kanchanwala
Kyle Mimun
Md Ashrafur Rahman
Yong Zhang
Thomas Abbruscato

Frontiers in Drug Delivery

doi 10.3389/fddev.2022.886099

11,692 views
5 citations

Original Research

Published on 06 Apr 2022

The Cell-Penetrating Peptide Tat Facilitates Effective Internalization of PSD-95 Inhibitors Into Blood–Brain Barrier Endothelial Cells but less Efficient Permeation Across the Blood–Brain Barrier In Vitro and In Vivo

in CNS Drug Delivery

Emma Lisa Al Humaidan
Sidse Lund Pedersen
Annette Burkhart
Charlotte Laurfelt Munch Rasmussen
Torben Moos
Peter Fuchs
Eduardo Filipe Alves Fernandes
Burak Ozgür
Kristian Strømgaard
Anders Bach

Frontiers in Drug Delivery

doi 10.3389/fddev.2022.854703

6,629 views
9 citations

Review

Published on 24 Mar 2022

Overcoming Blood-Brain Barrier Resistance: Implications for Extracellular Vesicle-Mediated Drug Brain Delivery

in CNS Drug Delivery

Jean Paul Dardet
Nelson Serrano
Ibolya Edit András
Michal Toborek

Frontiers in Drug Delivery

doi 10.3389/fddev.2022.855017

6,541 views
12 citations