Frontiers in Genome Editing | Genome Editing in Human Health and Disease

Original Research

Published on 30 Apr 2025

Efficient GBA1 editing via HDR with ssODNs by outcompeting pseudogene-mediated gene conversion upon CRISPR/Cas9 cleavage

in Genome Editing in Human Health and Disease

Joseph S. Lagas
Monica F. Sentmanat
Xiaoxia Cui

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1581743

1,443 views

Perspective

Accepted on 24 Apr 2025

Ethical Dimensions and Societal Implications: Ensuring the Social Responsibility of CRISPR Technology

in Genome Editing in Human Health and Disease

Irfan Biswas

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1593172

489 views

Original Research

Published on 04 Apr 2025

Mapping the therapeutic landscape of CRISPR-Cas9 for combating age-related diseases

in Genome Editing in Human Health and Disease

Qiyu He
Yida Wang
Zhimin Tan
Xian Zhang
Chao Yu
Xiaoqin Jiang

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1558432

1,820 views

Review

Published on 12 Dec 2024

Advances in CRISPR-Cas technology and its applications: revolutionising precision medicine

in Genome Editing in Human Health and Disease

Sarkar Sardar Azeez
Rahin Shareef Hamad
Bahra Kakamin Hamad
Mudhir Sabir Shekha
Peter Bergsten

Frontiers in Genome Editing

doi 10.3389/fgeed.2024.1509924

10,055 views
5 citations

Original Research

Published on 16 Oct 2024

Beyond the traditional distinctions of genome editing: evaluating a vulnerability framework

in Genome Editing in Human Health and Disease

Ioanna Angelioudaki
Ana Ruxandra Badea
Martina Bodo
Daniel Fernández-Soto
Emmanouela Sevasti Karyampa
Adam Kokkinakis
Nikolaos Kolisis
Xenia Kominea
Sandra Ozáez Armijos
Simon Vogel

Frontiers in Genome Editing

doi 10.3389/fgeed.2024.1426228

2,592 views

Review

Published on 09 Oct 2024

The potential of HBV cure: an overview of CRISPR-mediated HBV gene disruption

in Genome Editing in Human Health and Disease

Zhi Q. Yao
Madison B. Schank
Juan Zhao
Mohamed El Gazzar
Ling Wang
Yi Zhang
Addison C. Hill
Puja Banik
Jaeden S. Pyburn
Jonathan P. Moorman

Frontiers in Genome Editing

doi 10.3389/fgeed.2024.1467449

4,373 views
1 citation

Review

Published on 23 Aug 2024

In vivo liver targeted genome editing as therapeutic approach: progresses and challenges

in Genome Editing in Human Health and Disease

Chiara Simoni
Elena Barbon
Andrés F. Muro
Alessio Cantore

Frontiers in Genome Editing

doi 10.3389/fgeed.2024.1458037

4,848 views
3 citations

Original Research

Published on 28 May 2024

CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent mice

in Genome Editing in Human Health and Disease

Henriette Reventlow Frederiksen
Alexandra Glantz
Kåre Kryger Vøls
Søren Skov
Pernille Tveden-Nyborg
Kristine Freude
Ulrik Doehn

Frontiers in Genome Editing

doi 10.3389/fgeed.2024.1403395

2,880 views
2 citations

Editorial

Published on 20 Mar 2024

Editorial: Prevention of viral diseases by gene targeting

in Genome Editing in Human Health and Disease

Fan Luo
Qiankun Wang
Shuliang Chen

Frontiers in Genome Editing

doi 10.3389/fgeed.2024.1395468

2,388 views
1 citation

Review

Published on 06 Mar 2024

Epigenetic editing for autosomal dominant neurological disorders

in Genome Editing in Human Health and Disease

Jennifer J. Waldo
Julian A. N. M. Halmai
Kyle D. Fink

Frontiers in Genome Editing

doi 10.3389/fgeed.2024.1304110

4,507 views
2 citations

Original Research

Published on 01 Mar 2024

Nuclease-free precise genome editing corrects MECP2 mutations associated with Rett syndrome

in Genome Editing in Human Health and Disease

Swati Bijlani
Ka Ming Pang
Lakshmi V. Bugga
Sampath Rangasamy
Vinodh Narayanan
Saswati Chatterjee

Frontiers in Genome Editing

doi 10.3389/fgeed.2024.1346781

3,883 views
4 citations

Original Research

Published on 04 Jan 2024

Computational analysis of cas proteins unlocks new potential in HIV-1 targeted gene therapy

in Genome Editing in Human Health and Disease

Will Dampier
Rachel Berman
Michael R. Nonnemacher
Brian Wigdahl

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1248982

3,725 views
3 citations

Systematic Review

Published on 19 Dec 2023

What do people think about genetic engineering? A systematic review of questionnaire surveys before and after the introduction of CRISPR

in Genome Editing in Human Health and Disease

Pedro Dias Ramos
Maria Strecht Almeida
Ingrid Anna Sofia Olsson

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1284547

10,516 views
2 citations

Original Research

Published on 22 Nov 2023

Reciprocal mutations of lung-tropic AAV capsids lead to improved transduction properties

in Genome Editing in Human Health and Disease

Ashley L. Cooney
Christian M. Brommel
Soumba Traore
Gregory A. Newby
David R. Liu
Paul B. McCray
Patrick L. Sinn

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1271813

4,841 views
5 citations

Review

Published on 19 Sep 2023

Genome-wide CRISPR screens and their applications in infectious disease

in Genome Editing in Human Health and Disease

Kaveri Srivastava
Bhaswati Pandit

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1243731

6,618 views
6 citations

Review

Published on 17 Jul 2023

Combined approaches for increasing fetal hemoglobin (HbF) and de novo production of adult hemoglobin (HbA) in erythroid cells from β-thalassemia patients: treatment with HbF inducers and CRISPR-Cas9 based genome editing

in Genome Editing in Human Health and Disease

Alessia Finotti
Roberto Gambari

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1204536

6,915 views
7 citations