Frontiers in Genome Editing

Original Research

Published on 04 Jun 2025

Long read sequencing reveals transgene concatemerization and vector sequences integration following AAV-driven electroporation of CRISPR RNP complexes in mouse zygotes

in Genome Editing in Animals

Muhammad W. Luqman
Piroon Jenjaroenpun
Jessica Spathos
Nikhil Shingte
Mitchell Cummins
Pattaraporn Nimsamer
Lars M. Ittner
Thidathip Wongsurawat
Fabien Delerue

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1582097

266 views

Review

Published on 03 Jun 2025

Recent developments, challenges and opportunities in genome editing for crop science from a societal perspective

in Genome Editing in Plants

Srividhya Venkataraman
David Zaruk
Kathleen Hefferon

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1568072

530 views

Methods

Accepted on 02 Jun 2025

Comprehensive approaches to design efficient gRNA for SDN1-CRISPR/Cas9 genome editing in wheat

in Genome Editing in Plants

Tushadri Singh
Mamrutha HM
Rajinder Singh
Jai Prakash Jaiswal
Zeenat Wadhwa
Rakesh Kumar
Omvir Singh
Om Prakhash Ahlawat
Ratan Tiwari

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1579165

137 views

Methods

Published on 30 May 2025

Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage

in Genome Editing in Animals

Meredith K. Loth
Kendall T. Mesch
Celine Herrera-Garcia
Liza E. Brusman
Zoe R. Donaldson

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1602983

479 views

Brief Research Report

Accepted on 29 May 2025

A long shelf-life melon created via CRISPR/Cas9 RNP-based in planta genome editing

in Genome Editing in Plants

Kentaro Sasaki
Kaoru Urano
Naozumi Mimida
Satoko Nonaka
Hiroshi Ezura
Ryozo Imai

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1623097

198 views

Editorial

Published on 22 May 2025

Editorial: Plant breeding innovations—CRISPR as a powerful weapon for agricultural crops

in Genome Editing in Plants

Basavantraya N. Devanna
Yugander Arra
Maganti Sheshu Madhav

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1623540

1,035 views

Review

Published on 21 May 2025

Base editors in zebrafish: a new era for functional genomics and disease modeling

in Genome Editing in Animals

Yuwen Liu
Chao Li
Yiren Qiu
Sihong Chen
Yijun Luo
Donghua Xiong
Jun Zhao
Jianmin Ye
Xuegeng Wang
Wei Qin

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1598887

742 views

Review

Published on 20 May 2025

Genome editing in grain legumes for food security

in Genome Editing in Plants

Joshua Yeboah Asiamah
Sakina Haruna Mahdi
Kusum R. Tamang
Christian Bryan Carson
Prabesh Koirala
Emily Anne Reed
Aaron Tettey Asare
Anu Augustine
Milind B. Ratnaparkhe
Kailash C. Bansal

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1572292

1,341 views

Original Research

Published on 30 Apr 2025

Efficient GBA1 editing via HDR with ssODNs by outcompeting pseudogene-mediated gene conversion upon CRISPR/Cas9 cleavage

in Genome Editing in Human Health and Disease

Joseph S. Lagas
Monica F. Sentmanat
Xiaoxia Cui

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1581743

1,366 views

Perspective

Accepted on 24 Apr 2025

Ethical Dimensions and Societal Implications: Ensuring the Social Responsibility of CRISPR Technology

in Genome Editing in Human Health and Disease

Irfan Biswas

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1593172

446 views

Review

Published on 11 Apr 2025

Unraveling the future of genomics: CRISPR, single-cell omics, and the applications in cancer and immunology

in Genome Editing in Cancer and Immunology

A. Vipin Menon
Bicna Song
Lumen Chao
Diksha Sriram
Pamela Chansky
Ishnoor Bakshi
Jane Ulianova
Wei Li

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1565387

2,499 views

Original Research

Published on 04 Apr 2025

Mapping the therapeutic landscape of CRISPR-Cas9 for combating age-related diseases

in Genome Editing in Human Health and Disease

Qiyu He
Yida Wang
Zhimin Tan
Xian Zhang
Chao Yu
Xiaoqin Jiang

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1558432

1,750 views

Mini Review

Published on 02 Apr 2025

CRISPR-dependent base editing as a therapeutic strategy for rare monogenic disorders

in Genome Editing Tools and Mechanisms

Júlia-Jié Cabré-Romans
Raquel Cuella-Martin

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1553590

2,743 views

Brief Research Report

Published on 01 Apr 2025

Cas9 endonuclease: a molecular tool for in vitro cloning and CRISPR edit detection

in Genome Editing in Plants

Xingliang Ma
Dhouha Kthiri
Manpartik S. Gill
Curtis J. Pozniak
Sateesh Kagale

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1565297

1,170 views

Review

Published on 18 Mar 2025

CRISPR/Cas9: a sustainable technology to enhance climate resilience in major Staple Crops

in Genome Editing in Plants

Navjot Kaur
Muslim Qadir
Dali V. Francis
Anshu Alok
Siddharth Tiwari
Zienab F. R. Ahmed

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1533197

3,741 views
1 citation

Review

Published on 10 Mar 2025

Emerging applications of gene editing technologies for the development of climate-resilient crops

in Genome Editing in Plants

R. L. Chavhan
S. G. Jaybhaye
V. R. Hinge
A. S. Deshmukh
U. S. Shaikh
P. K. Jadhav
U. S. Kadam
J. C. Hong

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1524767

3,442 views
1 citation