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REVIEW article

Front. Hum. Neurosci.
Sec. Motor Neuroscience
Volume 18 - 2024 | doi: 10.3389/fnhum.2024.1406670
This article is part of the Research Topic Influence of Psycho-emotional Factors on Motor Control : Cerebral Mechanism and Behavioral Response Underlying (Motiv)Action View all 4 articles

Effects and neural mechanisms of different physical activity on major depressive disorder based on cerebral multimodality monitoring: A narrative review

Provisionally accepted
Haohan Yu Haohan Yu 1Jiaxin Liang Jiaxin Liang 2*Chuang Liu Chuang Liu 3*Yiming Fan Yiming Fan 1*
  • 1 Beijing Normal University, Beijing, China
  • 2 Kunming University of Science and Technology, Kunming, Yunnan Province, China
  • 3 China University of Geosciences, Beijing, Beijing Municipality, China

The final, formatted version of the article will be published soon.

    Major depressive disorder (MDD) is currently the most common psychiatric disorder in the world. It characterized by a high incidence of disease with the symptoms like depressed mood, slowed thinking, and reduced cognitive function. Without timely intervention, there is a 20-30% risk of conversion to treatment-resistant depression (TRD) and a high burden for the patient, family and society. Numerous studies have shown that physical activity (PA) is a non-pharmacological treatment that can significantly improve the mental status of patients with MDD and has positive effects on cognitive function, sleep status, and brain plasticity. However, the physiological and psychological effects of different types of PA on individuals vary, and the dosage profile of PA in improving symptoms in patients with MDD has not been elucidated. In most current studies of MDD, PA can be categorized as continuous endurance training (ECT), explosive interval training (EIT), resistance strength training (RST), and mind-body training (MBT), and the effects on patients' depressive symptoms, cognitive function, and sleep varied. Therefore, the present study was based on a narrative review and included a large number of existing studies to investigate the characteristics and differences in the effects of different PA interventions on MDD. The study also investigated the characteristics and differences of different PA interventions in MDD, and explained the neural mechanisms through the results of multimodal brain function monitoring, including the intracranial environment and brain structure. It aims to provide exercise prescription and theoretical reference for future research in neuroscience and clinical intervention in MDD.

    Keywords: Depressive Disorder, Exercise, brain plasticity, Cognitive Function, Neural mechanis

    Received: 25 Mar 2024; Accepted: 12 Jun 2024.

    Copyright: © 2024 Yu, Liang, Liu and Fan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Jiaxin Liang, Kunming University of Science and Technology, Kunming, 650500, Yunnan Province, China
    Chuang Liu, China University of Geosciences, Beijing, 100083, Beijing Municipality, China
    Yiming Fan, Beijing Normal University, Beijing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.