REVIEW article

Front. Hum. Neurosci.

Sec. Brain Health and Clinical Neuroscience

Volume 19 - 2025 | doi: 10.3389/fnhum.2025.1554147

This article is part of the Research TopicNeurobiological Mechanisms of Adjuvant Therapies for Personalized Stroke Rehabilitation: Towards Comprehensive RecoveryView all 5 articles

Aphasia Rehabilitation: A Narrative Review of Adjuvant Techniques

Provisionally accepted
Stacy  M HarnishStacy M Harnish*Courtney  JewellCourtney JewellNatalie  FreitagNatalie FreitagGrace  TerryGrace TerryGillian  AndersonGillian Anderson
  • The Ohio State University, Columbus, United States

The final, formatted version of the article will be published soon.

Adjuvant techniques, or strategies that may be employed alongside language therapy for individuals with aphasia, are increasingly gaining attention for their ability to promote an enhanced brain environment for neuroplasticity. This narrative review describes active ingredients, mechanisms of action, potential modulating factors and evidence for efficacy of noninvasive brain stimulation techniques, such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS); aerobic exercise; intention treatment; and pharmacotherapies, including monoaminergic, cholinergic, glutaminergic, and nootropic medications that have been used in concert with language therapy for aphasia.

Keywords: Aphasia, adjuvant, Treatment, NIBS (Non-invasive Brain Stimulation, aerobic exercise, Pharmacotherapy

Received: 01 Jan 2025; Accepted: 30 Jun 2025.

Copyright: © 2025 Harnish, Jewell, Freitag, Terry and Anderson. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Stacy M Harnish, The Ohio State University, Columbus, United States

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