SYSTEMATIC REVIEW article
Front. Med. Technol.
Sec. Nano-Based Drug Delivery
Volume 7 - 2025 | doi: 10.3389/fmedt.2025.1657594
The Utilization of Exosomes in Hydrogels: A Bibliometric Analysis of Publications from 2015 to May 2025
Provisionally accepted
- Khalifa University, Abu Dhabi, United Arab Emirates
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This paper is a bibliometric analysis of the utilization of exosomes in hydrogels for various applications, conducted by assessing the relevant documents in this evolving field of research. Since targeted drug delivery, cell communication, and tissue regeneration are of high importance in the field of biomedicine and medical sciences, incorporating exosomes can offer a valuable addition in such applications due to their high bioactivity and biocompatibility. Applications include ocular drug delivery, boosting optic nerve damage, and disease detection, such as cancer and diabetes. Exosome-based technologies have been of interest since the early 2000s, with an increased momentum in recent years. In this study, data were exported from the Web of Science and Scopus databases and plotted in order to identify the research trends and publication impact in such an evolving area. The analysis reveals that among several countries, China has the greatest number of publications within the period of 2015 to 9th of May 2025, with a contribution of approximately 76.21% and 61.92% based on the WOS and Scopus databases, respectively. Both publications and citation trends show a significant increase with time, reflecting the increased interest in this field. This study aims to provide an overview of the current impact of research on utilizing exosomes in hydrogel systems.
Keywords: Exosomes, Nanoparticles, Hydrogels, Polymers, extracellular vesicles
Received: 06 Jul 2025; Accepted: 28 Aug 2025.
Copyright: © 2025 El Turk, Sajini and Butt. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Said El Turk, Khalifa University, Abu Dhabi, United Arab Emirates
Haider Butt, Khalifa University, Abu Dhabi, United Arab Emirates
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