ORIGINAL RESEARCH article
Front. Musculoskelet. Disord.
Sec. Systemic Inflammatory Joint Diseases
Volume 3 - 2025 | doi: 10.3389/fmscd.2025.1622400
This article is part of the Research TopicInnovations in Musculoskeletal Imaging: Delving into Advanced MRI TechniquesView all articles
Evaluation of the efficacy of platelet-rich plasma (PRP) in the treatment of training-induced knee traumatic osteoarthritis: A retrospective study based on a multidimensional quantitative evaluation
Provisionally accepted
Chao Cheng1
Yongzhi He2Huage Wang1Zhonglin Xiao1
Linjie Wang1
Rizhao Pang1Li Zhu1Zhengdong Wang1Jinqi Zheng1
Wenchun Wang1*Shiyu Huang3- 1People's Liberation Army The General Hospital of Western Theater Command, chengdu, China
- 2North sichuan medical college, Chengdu, China
- 3Southwest Jiaotong University, Chengdu, China
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Objective: In this study, we retrospectively evaluated the efficacy of platelet-rich plasma (PRP) for the treatment of training-induced traumatic knee osteoarthritis (KTOA) by means of a functional scale and MRI cartilage score, and analysed its effects on the improvement of knee function, pain relief and cartilage repair. METHODS: In this study, 120 patients with training-induced KTOA (screened from 519 cases) were retrospectively analysed from May 2019 to December 2023, and knee function, pain and cartilage repair were evaluated by LKSS, VAS and MRI cartilage scores before and 3 months after treatment, and the statistical methods used were paired t-tests or Wilcoxon tests (P < 0.05). Results: Among 120 patients with training-induced KTOA treated with PRP, the Lysholm Knee Score (LKSS) significantly improved from (62.34 ± 18.69) to (81.2 ± 18.20) at 3 months after treatment, and the effective rate was 55.0%; the visual analogue score (VAS) of pain decreased from (5.24 ± 1.57) to (2.66 ± 1.43), and the effective rate of 81.7%; MRI cartilage damage score decreased from (3.24±0.72) to (3.02±0.86), and the effective rate was 36.7%; the differences were statistically significant (P<0.05). Conclusion: KTOA due to PRP therapeutic training improves joint pain and promotes the recovery of knee joint function. Meanwhile, it has a repairing effect on articular cartilage damage.
Keywords: Platelet-Rich Plasma, Traumatic knee osteoarthritis, Magnetic Resonance Imaging, Lysholm score, pain visual analogue score, cartilage repair
Received: 03 May 2025; Accepted: 29 Aug 2025.
Copyright: © 2025 Cheng, He, Wang, Xiao, Wang, Pang, Zhu, Wang, Zheng, Wang and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Wenchun Wang, People's Liberation Army The General Hospital of Western Theater Command, chengdu, China
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