CASE REPORT article
Front. Nephrol.
Sec. Blood Purification
Volume 5 - 2025 | doi: 10.3389/fneph.2025.1645622
Severe consequences of uncontrolled tertiary hyperparathyroidism in a limited resources setting: A Case Report
Provisionally accepted
- 1Universidad Catolica de Honduras, Tegucigalpa, Honduras
- 2Universidad Nacional Autonoma de Honduras, Tegucigalpa, Honduras
- 3Hospital Civil de Guadalajara Unidad Hospitalaria Fray Antonio Alcalde, Guadalajara, Mexico
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Tertiary hyperparathyroidism (THPT) is a severe complication of uncontrolled secondary hyperparathyroidism, typically associated with advanced-stage chronic kidney disease (CKD). We present the case of a Honduran patient with a long-standing history of CKD secondary to severe preeclampsia, who developed THPT following the discontinuation of her treatment due to financial constraints and the COVID-19 pandemic. The patient exhibited severe maxillofacial deformities, functional limitations, and widespread skeletal abnormalities. Despite initial management with medications such as paricalcitol and alfacalcidol, the lack of access to appropriate therapies and the postponement of a planned parathyroidectomy worsened her condition. This case highlights the importance of early diagnosis and timely intervention, particularly in resource-limited settings, emphasizing the urgent need for kidney transplant programs and improved preventive strategies in developing countries.
Keywords: Chronic Kidney Disease, Parathyroid gland, Secondary hyperparathyroidism, Renal osteodistrophy, Hemodyalisis
Received: 12 Jun 2025; Accepted: 08 Aug 2025.
Copyright: © 2025 Mejía Raudales, PORTILLO, Chavez and Gough. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Beatriz Mejía Raudales, Universidad Catolica de Honduras, Tegucigalpa, Honduras
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