CASE REPORT article
Front. Nephrol.
Sec. Kidney Transplantation
Volume 5 - 2025 | doi: 10.3389/fneph.2025.1648263
This article is part of the Research TopicCase reports in kidney transplantationView all articles
Kidney Transplantation between identical twins with APOL1 homozygote risk alleles -a case report Authors
Provisionally accepted
- 1Department of Medicine, Division Nephrology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, United States
- 2Department of Medicine, Nephrology, Harbor-UCLA Medical Center, Torrance, United States
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Kidney transplantation is the optimal therapy for individuals with end-stage kidney disease. Recent studies suggest a negative impact of high-risk Apolipoprotein L1 genotypes on outcomes for both living kidney donors and kidney transplant recipients. In this case, we describe a pair of identical twins with a high-risk APOL1 genotype who underwent successful living kidney transplantation with excellent short-term outcomes.
Keywords: Kidney transplant, kidney transplanation, Living donor, APO L1, genetic kidney disease
Received: 16 Jun 2025; Accepted: 11 Jul 2025.
Copyright: © 2025 Lei, Shankar, Sethi and Lum. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Erik Lum, Department of Medicine, Division Nephrology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, United States
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