ORIGINAL RESEARCH article
Front. Physiol.
Sec. Integrative Physiology
Volume 16 - 2025 | doi: 10.3389/fphys.2025.1600369
Impact of cricothyroid membrane puncture anesthesia on elderly patients undergoing endotracheal intubation after anesthesia induction: a clinical study
Provisionally accepted- Chifeng Cancer Hospital, Inner Mongolia, China
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Objective: This study investigated the clinical effects of cricothyroid membrane puncture (CMP) anesthesia surface anesthesia following anesthesia induction on elderly patients undergoing endotracheal intubation (ETI).Methods: Eighty elderly patients scheduled for general anesthesia with endotracheal intubation at our hospital from January to December 2023 were enrolled and randomly assigned (n = 40 each) to a study group or a control group. After intravenous anesthesia induction, the study group received 2% lidocaine via CMP for surface anesthesia, while the control group received no CMP administration. The incidence of coughing during extubation in the emergence phase, first-attempt intubation success, hypoxemia, hypotension, and vasoactive drug use were recorded. Hemodynamic parameters and adverse events were compared between groups.Results: All patients achieved successful first-attempt intubation. There were no significant differences in hypoxemia incidence between groups (P > 0.05). The study group had lower rates of hypotension and vasoactive drug use compared with the control group (P < 0.05), as well as a lower incidence of coughing during extubation (P < 0.05). At T0, heart rate (HR), systolic blood pressure (SBP), mean arterial pressure (MAP), and SpO2 did not differ significantly (P > 0.05). At T1-T3, HR, SBP, and MAP were significantly lower in the study group (P < 0.05), with no significant differences in SpO2 (P > 0.05). Total adverse event rates were similar between groups (P > 0.05).CMP surface anesthesia following anesthesia induction in elderly patients provides favorable clinical effects by improving hemodynamic stability and reducing coughing during emergence, without increasing adverse events.
Keywords: Endotracheal intubation, Cricothyroid membrane puncture, Surface anesthesia, Hemodynamics, Recovery period, elderly patient
Received: 26 Mar 2025; Accepted: 18 Aug 2025.
Copyright: © 2025 Wang, Zhao, Liang, Li, Bi and Lian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Hao Lian, Chifeng Cancer Hospital, Inner Mongolia, China
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