Your new experience awaits. Try the new design now and help us make it even better

MINI REVIEW article

Front. Physiol.

Sec. Exercise Physiology

Volume 16 - 2025 | doi: 10.3389/fphys.2025.1631817

Recent Advances in the Mechanisms and Rehabilitation Strategies of Exercise Interventions for Osteoporosis in Elderly Women

Provisionally accepted
Bing  ZhengBing Zheng1Jing  ChenJing Chen2,3Yiheng  LiYiheng Li4*
  • 1Physical education department, Tangshan Normal University, Tangshan, China
  • 2Sichuan College of Architecture Technology, Deyang, China
  • 3Sichua College of Architechure Technology, Deyang, China
  • 4Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China

The final, formatted version of the article will be published soon.

Osteoporosis is a prevalent musculoskeletal disorder among elderly women, characterized by reduced bone mass and deterioration of bone microarchitecture, leading to decreased quality of life and increased fracture risk. This review summarizes recent advances in the research on exercise interventions for the prevention and treatment of osteoporosis in this population. The mechanisms by which exercise exerts beneficial effects include mechanical stimulation that enhances osteoblast activity, hormonal regulation to maintain bone metabolic balance, improved skeletal blood circulation, and increased muscle strength and postural stability. Various forms of exercise demonstrate distinct therapeutic effects: aerobic exercise enhances bone strength through regular loading stimuli; resistance training directly stimulates bone formation; balance and flexibility training improve coordination and reduce the risk of falls; and emerging modalities such as whole-body vibration have shown potential benefits for bone health. The development of exercise prescriptions should be tailored to the individual's physical condition, incorporating appropriate types, intensities, durations, and frequencies of exercise, with an emphasis on pre-exercise health assessments and safety monitoring throughout the intervention. Although the efficacy of exercise interventions is widely recognized, current research still faces limitations in areas such as personalized program design, synergistic effects of different exercise modalities, and strategies to improve long-term adherence. Further studies are warranted to optimize clinical application.

Keywords: Elderly women, Osteoporosis, Exercise Intervention, bone metabolism, precisionrehabilitation, review

Received: 27 May 2025; Accepted: 09 Sep 2025.

Copyright: © 2025 Zheng, Chen and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Yiheng Li, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.