REVIEW article
Front. Physiol.
Sec. Exercise Physiology
Volume 16 - 2025 | doi: 10.3389/fphys.2025.1650078
This article is part of the Research TopicAdaptations and Responses to Respiratory InterventionsView all 5 articles
Exercise Interventions for Pulmonary Function Impairment: Rehabilitation Strategies from the Acute Phase to Long-Term Sequelae
Provisionally accepted- 1Henan Normal University, Xinxiang, China
- 2Zhengzhou Tourism Vocational College, Zhengzhou, China
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Pulmonary function impairment, as a major global public health concern, significantly affects respiratory function, quality of life and mortality. Its pathological features include impaired gas exchange, reduced exercise tolerance, and chronic inflammatory responses. Conventional non-pharmacological interventions, such as protective mechanical ventilation, prone positioning, and extracorporeal membrane oxygenation (ECMO), can improve oxygenation but are limited by risks of complications, poor patient tolerance, and high dependence on equipment. Pharmacological therapies may regulate inflammatory responses; however, their long-term application is constrained by safety concerns and interindividual variability in efficacy. The discussion of the benefits and mechanisms of exercise interventions includes an explanation of their applicability to patients across various types and stages of pulmonary function impairment. In addition, this study systematically elucidates the mechanisms and implementation strategies of exercise interventions across different stages of pulmonary impairment, including the acute phase, recovery phase, and long-term management phase. It further proposes a personalized exercise prescription framework based on biomarkers. The study emphasizes the development of dynamic adjustment systems and stratified management strategies tailored for special populations such as the elderly and children, thereby providing a theoretical foundation for optimizing pulmonary rehabilitation outcomes.
Keywords: pulmonary function impairment, Exercise Intervention, Respiratory rehabilitation, Cardiopulmonary adaptation, personalized exercise prescription
Received: 19 Jun 2025; Accepted: 02 Sep 2025.
Copyright: © 2025 Guo, Huo and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zhanyi Zhang, Henan Normal University, Xinxiang, China
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