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ORIGINAL RESEARCH article

Front. Physiol.

Sec. Computational Physiology and Medicine

Volume 16 - 2025 | doi: 10.3389/fphys.2025.1650134

Multi-class: Spectral-Spatial Temporal Pyramid Network and Multi-class Classifier based Cardiovascular Disease Classification

Provisionally accepted
  • VIT-AP University, Amaravati, India

The final, formatted version of the article will be published soon.

cardiovascular disease (CVD) represents a major global cause of morbidity and mortality, encompassing conditions such as coronary artery disease, heart failure, and stroke. Early diagnosis of CVD is critical to improve treatment outcomes and prevent disease progression. Leveraging both electrocardiogram (ECG) and phonocardiogram (PCG) data, we propose MCC-CVD, a multi-modality deep learning framework for multi-class CVD classification. Our approach integrates a Spectral Spatial Temporal Pyramid Network (SST-PNet), a Weight Correction Module with Attention Mechanism (WCM-AM), and a novel Multi-class EnDe-CNN classifier to extract complementary features and enhance predictive accuracy. A real-world dataset of 920 patients with 13 clinical parameters was used to evaluate the model. After unified data quality enhancement and normalization, MCC-CVD achieved an average accuracy of 92.4%, F1-score of 0.87, precision of 0.89, recall of 0.85, and an AUC of 0.94, outperforming baseline classifiers such as SVM, Random Forest, and Logistic Regression. These results demonstrate the model’s strong discriminative capability and robustness across multiple CVD subtypes.

Keywords: Cardiovascular disease (CD), Spectral Spatial Temporal Convolutional Pyramid Network, multi-modality, Multi-class classifier, Weight Correction Module.

Received: 24 Jun 2025; Accepted: 25 Sep 2025.

Copyright: © 2025 sk and S P. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Siddique Ibrahim S P, siddique.ibrahim@vitap.ac.in

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