Your new experience awaits. Try the new design now and help us make it even better

ORIGINAL RESEARCH article

Front. Physiol.

Sec. Computational Physiology and Medicine

Clinically Guided Adaptive Contrast Adjustment for Fetal Plane Classification: A Modular Plug-and-Play Solution

Provisionally accepted
  • 1School of Mathematics and Statistics, Xiamen University of Technology, Xiamen, China
  • 2Hunan University of Finance and Economics, Changsha, China
  • 3Dongguan University of Technology, Dongguan, China
  • 4School of Business, Society and Engineering, Malardalens universitet, Västerås, Sweden

The final, formatted version of the article will be published soon.

Fetal ultrasound standard plane recognition plays a vital role in ensuring accurate prenatal assessment but remains challenging due to intrinsic factors such as poor tissue contrast, indistinct anatomical boundaries, and variability in image quality caused by operator differences. To address these issues, we introduce a plug-and-play Adaptive Contrast Adjustment Module (ACAM), inspired by how clinicians manually adjust image contrast to highlight clearer structural cues. The proposed module integrates a lightweight, texture-aware subnetwork that learns to generate clinically meaningful contrast parameters, producing multiple contrast-enhanced representations of the same image through a differentiable transformation process. These enhanced views are then fused within subsequent classifiers to enrich discriminative features. Experiments conducted on a multi-center dataset containing 12,400 fetal ultrasound images across six anatomical planes demonstrate consistent performance gains: the accuracy of lightweight models rises by 2.02%, conventional architectures by 1.29%, and state-of-the-art models by 1.15%. The key novelty of ACAM lies in its content-adaptive and clinically aligned contrast modulation, which replaces random preprocessing with physics-guided transformations mimicking sonographers' diagnostic workflows. By leveraging multi-view contrast fusion, our approach enhances robustness against image quality variations and effectively links low-level texture cues with high-level semantic understanding, offering a new framework for medical image analysis in realistic clinical settings. Our code is available at: https://github.com/sysll/ACAM.

Keywords: Fetal ultrasound, Clinically-inspired module, Adaptive contrast adjustment, Robust medical image analysis, plug and play (PnP)

Received: 22 Aug 2025; Accepted: 03 Nov 2025.

Copyright: © 2025 Chen, Zhao, Chen and Gustaf. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Måns Gustaf, gustafedu@yeah.net

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.