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MINI REVIEW article

Front. Radiol., 27 January 2026

Sec. Interventional Radiology

Volume 5 - 2025 | https://doi.org/10.3389/fradi.2025.1689635

This article is part of the Research TopicImaging, Surgical and Treatment Strategies Among Young Patients Affected by Breast CancerView all 3 articles

Radiologic imaging and its current importance in breast cancer management


Nisha DagarNisha Dagar1Monu Sarin
Monu Sarin2*Piyush YadavPiyush Yadav3Rajdeep Thidwar
Rajdeep Thidwar3
  • 1Department of Radiology, Centre of Allied Health Sciences/Amrita School of Medicine, Amrita Institute of Medical Sciences and Research Centre, Faridabad, India
  • 2Department of Radio-Diagnosis, SGT University, Budhera, Gurugram, India
  • 3Guru Nanak Paramedical College, Dhahan Kaleran (PB), India

Introduction: This study examines the approaches used for cancer screening in women, insisting on the roles of mammography, breast ultrasound, breast MRI, computed tomography (CT), and positron emission tomography. Mammography is still the key method for early detection, with modern digital technology boosting image quality and diagnostic accuracy. Breast MRI provides increased sensitivity for high-risk individuals, and it is recommended to be used with mammography for full screening.

Methods: This review article provides a comprehensive assessment of breast imaging techniques, focussing on screening recommendations and advancements in mammography, ultrasonography, MRI, CT, and PET. These methods provide a multidisciplinary approach to improving breast cancer detection, diagnosis, and personalized care. Early detection is necessary for less aggressive treatment. Digital breast tomosynthesis consists of contrast-enhanced spectral mammography, molecular breast imaging, MRI, and USG.

Results: Mammography remains the primary imaging modality for detecting breast abnormalities, including cancer. The use of standardized interpretation systems improves the communication of findings. The present paper summarizes the primary disputes surrounding breast cancer management.

Conclusion: According to the literature, low-dose mammography is the only radiographic technique that has significantly impacted the diagnosis, staging, and patient follow-up for asymptomatic breast cancer screening. Mammography is also the only accurate screening test for breast imaging. Implications for practice.

Introduction

Worldwide, the cancer of breasts is the most common to strike women. According to studies, almost 2 million women are diagnosed yearly (1). The disease's heterogeneity, with multiple subtypes, adds to its complexity; however, early detection programs combined with advances in staging and imaging techniques have improved Rates of recovery for breast cancer patients by providing better options for treatment and planning than when surgery was the mainstay of care (2). Breast cancer screening lowers breast cancer-related mortality, and early discovery allows for less aggressive treatment. However, screening procedures are far from optimal due to large false-positive rates and poor sensitivity (3). Breast lumps can have a variety of causes, ranging from benign to malignant. The most common benign breast lump is fibroadenoma, and the most common cancer is invasive ductal carcinoma. A precise and efficient evaluation can boost cancer detection while reducing unnecessary tests and procedures (4). Mammography, particularly screening mammography, is the most effective tool for early breast cancer detection and is recommended once a year for women at average risk beginning at age 40. Digital mammography improves interpretation, particularly in patients with thick breast tissue (5). Radiologic imaging, such as ultrasonography, mammography, and MRI, is critical for early identification and diagnosis of breast cancer, resulting in much higher survival rates. It also permits imaging-guided interventions, which enhance the radiologist's multidisciplinary breast cancer management role (6). Radiologic imaging is essential in breast cancer management for correct staging, determining treatment response, and making therapeutic decisions. In metastatic breast cancer, CT, WB-DWI-MRI, and FDG-PET/CT improve disease assessment, altering treatment protocols and patient outcomes (7). Radiologic imaging is critical for detecting early breast cancer, staging it, and evaluating therapy options. PET-CT, BSGI, and DWI techniques improve detection accuracy, especially in dense breasts, allowing for more prompt and personalized therapeutic interventions and, ultimately, better patient outcomes. Each approach has its merits and limits; some are more effective in spotting small or thick tumours (8). Preoperative breast MRI is very important in breast cancer care because it gives a more reliable diagnosis of tumour size, greatly impacting surgical treatment decisions compared to mammography and ultrasound, which have greater rates of size misestimation (9). Radiologic imaging is critical in breast cancer management, especially in detecting metastatic lymph node involvement and guiding neoadjuvant systemic therapy, which has led to less extensive surgical methods and improved patient outcomes in recent decades. The significance of lymph node management in breast cancer, the function of neoadjuvant therapy, the evolution of surgical methods, and the advances in imaging technologies that are driving contemporary treatment approaches (10). Mixed imaging approaches can provide additional information to aid staging and therapeutic planning. The imaging goal was to develop a minimally intrusive therapy that would produce greater results while reducing adverse effects. The most essential component in reducing the mortality rate from some cancers is early detection by imaging-based screening. Carcinoma of the breast is the most often diagnosed malignancy among women. Breast imaging includes sonography, mammography, and scanning with magnetic resonance tomography (MRT) of the breast and is considered the second leading cause of cancer deaths in women. Further technological advancements will result in faster imaging speeds to match the demands of physiological processes. Particularly among the challenges in diagnosing breast cancer is sensibility. Complementary imaging examinations can help overcome this constraint utilized that traditionally include screening ultrasound, and combined mammography and ultrasound (11). Screening is critical in breast cancer management by assisting in early detection, correct diagnosis, treatment planning, and monitoring response to therapy, eventually improving patient outcomes and guiding interventional procedures. Radiological imaging aids in cancer diagnosis and staging, and it also plays a part in therapy planning (12). Mammography is currently the most common and available method for early detection of breast cancer. The most frequent breast abnormalities that can suggest breast cancer are lumps and calcifications. The goal is to promptly and accurately overcome the development of breast cancer, which is affecting an increasing number of women worldwide. Masses occur in a mammogram as small, granular clusters that are difficult to discern in a raw image. A mammography is one of the most effective breast cancer diagnostic methods available today. Breast cancer is discovered in its advanced stages using mammography images. Some simple segmentation techniques have been created to make a supporting tool for a simpler and less time-consuming way of identifying abnormal masses in mammography images (13).

Methods used in this paper (screening recommendations)

Role of mammography

Mammography is the primary imaging approach for detecting breast abnormalities, notably breast cancer. It is the only method recognized as a valid screening tool because of substantial study and technological advances. There are two primary forms of mammography: screening Mammography is used for routine examinations in women who do not have symptoms to detect potential problems early, while diagnostic mammography is used for people who do have symptoms or for follow-up after therapy to examine specific concerns. Digital systems use electronic detectors to generate images that can be viewed immediately. This method accelerates image processing and storage, enabling more efficient data analysis. High-quality pictures are required in mammography. Standardize how breast exams are read and reported. This technique divides findings into clear categories, allowing doctors to express the significance of the data and plan the next actions (14). An American study found a modest drop in mammography for screening in women aged 40–49 years after the publication of the USPSTF guidelines. It is noteworthy to note that the screening rate for this group increased during the next two years (15). Even while mammography screening has improved the detection of Ductal carcinoma in situ (DCIS) and initially invasive malignancies, there has been no significant shift in the prevalence of aggressive malignancy over the last thirty years. Data analysis from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) program, conducted between 1979 and 2008, indicated a shocking increase of 122 early breast cancers per 100,000 women. However, throughout the same period, the number of late-stage tumours reduced by 8% (16).

Role of breast ultrasound

Women with dense fibroglandular tissue and low mammography detection rates are ideal candidates for breast screening ultrasonography. Dense breasts often have decreased mammography sensitivity, occasionally decreasing as low as 30%–48% (17, 18). In mammograms, dense breasts often contain at least 50% glandular tissue (ACR classifications 3 and 4).

The American College of Radiology (ACR) also advises breast ultrasonography in addition to mammography for women who are at high risk of breast cancer but cannot tolerate an MRI. Women who have had breast irradiation between the ages of 10 and 30, have a mutation in the BRCA gene, are related to a BRCA carrier, or have a lifetime risk of at least 20% for breast cancer are considered high risk (19). ACRIN 6666, a multicentre trial that investigated ultrasonography in women at extremely high risk of breast cancer, discovered that screening ultrasound might uncover 3.7 additional tumours per 1,000 screens in this cohort (20). Six studies were undertaken from 1995 to 2004 to evaluate screening ultrasonography in women with an average risk of breast cancer. There were 2,838 examinations in these six investigations, with only 126 patients having 150 more tumours discovered by breast ultrasonography. Ninety percent of the women had thick or heterogeneously dense parenchyma (21). Because of its high sensitivity and early detection rates—particularly for women with dense breasts—and its affordability in contexts where mammography is not available, breast ultrasonography (US) is a crucial tool for cancer screening, especially in low-resource settings (22). This brings validity to the idea that screening using breast ultrasonography is advantageous for women with thick breasts.

Breast MRI

Additionally, there was not a randomized study to ascertain whether MRI lowers the overall fatality rate from breast cancer (23). In high-risk patients, the sensitivity of mammography screening in conjunction with MRI is higher (90%–100%) than mammography screening alone (25%–59%). However, the combined approach has a lower specificity (73%–93%) (24). For women with a high risk of breast cancer, the American Cancer Society (ACS) advised yearly screening MRI in 2007 to complement annual screening mammography, based on the findings of nine trials (25). In 2010, starting at age 30, the American College of Radiology and the Society of Breast Imaging advised yearly MRIs and mammograms for BRCA ½ carriers. For women who have a 20% or higher lifetime risk of breast cancer, a similar guideline is applicable. Women who claim have undergone prior chest radiation therapy should start yearly mammograms and MRI screenings at least 8 years after finishing treatment, but no earlier than age 25. From the moment of diagnosis, MRI and yearly mammograms should be taken into consideration for women with a history of breast cancer, biopsy-proven lobular neoplasia, or ovarian cancer (26).

Role of CT in breast

Ultrasonography and mammography are augmented by the highly sensitive imaging technique, contrast-enhanced computed tomography (CE-CT). Researchers in medicine have assessed computed tomography's capacity to differentiate between benign and malignant tumours. However, contrast-enhanced computed tomography is sufficient for assessing the extent of tumour extension within the breast and for identifying lesions that are missed by other techniques because of its high spatial resolution and relatively low specificity.

Helical CT technology facilitates faster, gap-free scans and lowers x-ray doses when compared to traditional CT (27). Breast-conserving treatment (BCT), local therapy, or mastectomy are now the options available to women with early-stage breast cancer. It is crucial to perform a preoperative evaluation of tumour extension to choose candidates who qualify for BCT. This will involve multicentricity, a large intraductal component, and breast-daughter lesions (28). CT scans help detect pathological alterations suggestive of breast cancer by providing fine-grained images of the internal anatomy of the breast. Using a Convolutional Neural Network, this study classified breast cancer from CT scan pictures with an accuracy of 97.26% (29). With a sensitivity of 84.21%, specificity of 99.3%, and accuracy of 98.68%, chest CT scans are more sensitive than mammograms in the diagnosis of breast cancer. CT is a possible substitute for breast cancer screening since it may detect breast lumps and lymphadenopathy with accuracy (30).

PET Imaging of Breast Cancer

As the use of molecular imaging for patients with breast cancer grows, breast radiologists must have a basic understanding of molecular imaging, especially PET. Current research on the FDA-approved PET tracer 16α-18F-fluoro-17β-estradiol (FES), which targets ER, includes guidelines examining the Association of Nuclear Medicine and Molecular Imaging on the appropriate use of FES-PET/CT for breast cancer and areas of active investigation for other potential applications (31). Primarily, the focus is on the utility of 18F-fluorodeoxyglucose (FDG) PET in staging, recurrence detection, and treatment response evaluation. Furthermore, there will be a delve into the growing interest in precision therapy and the development of novel radiopharmaceuticals targeting tumour biology. This includes discussing the potential of PET/MRI and artificial intelligence in breast cancer imaging, offering insights into improved diagnostic accuracy and personalized treatment approaches (32).

New digital technologies like Digital Breast Tomosynthesis (DBT) and Contrast-Enhanced Spectral Mammography (CESM) improve diagnostic capability over conventional mammography through:

- DBT (3D mammography): Reduces tissue overlap, enhancing lesion visibility, especially in dense breasts, and reduces false positives.

- CESM: Levitates use of contrast agents to accentuate tumor vascularity, improving detection of malignancies easily missed in conventional mammograms.

- SPR (Surface Plasmon Resonance)-based biosensing eliminates Imaging demerits through the Enabling label-free, real-time molecular sensing of biomarkers of cancer in fluids or blood, offering early high sensitivity and specificity, even prior to detecting a tumor on a picture, being non-invasive and potentially more cost-effective for screening and monitoring earlier.

- Thus, SPR biosensing complements imaging in offering earlier biochemical detection, avoiding the drawback of radiation exposure and reduced sensitivity in thick tissues.

Result

Mammography is still the principal imaging modality for detecting breast abnormalities, including breast cancer. Screening mammography for asymptomatic women to discover early concerns and diagnostic mammography for symptomatic individuals or follow-up exams. Digital mammography improves image quality, processing, and storage, resulting in higher diagnostic accuracy. The use of standardized interpretation systems enhances the communication of findings. While mammography has greatly improved the diagnosis of early-stage malignancies, aggressive malignancy rates have remained stable over the last three decades. SEER program statistics from 1979 to 2008 show a 122% rise in early detections but only an 8% decrease in late-stage cases. Ultrasound complements mammography, especially in women with thick breasts, where mammographic sensitivity declines to 30%–48%. It is also indicated for high-risk women who cannot get an MRI. The ACRIN 6666 study found that ultrasound can detect an extra 3.7 tumours per 1,000 tests in high-risk patients. Its low cost and great sensitivity make it essential in low-resource environments and dense breast instances. MRI provides higher sensitivity (90%–100%) than mammography alone (25%–59%) for high-risk patients, but lower specificity. Annual MRI and mammography are indicated for women individuals who were with BRCA mutations who are at risk for breast cancer, beginning at age 30 or earlier based on specific risk factors. Contrast-enhanced computed tomography (CE-CT) is useful in determining tumour extent, especially for breast-conserving treatment (BCT). Helical CT is one example of an advancement that increases imaging speed while decreasing radiation exposure. CT's superior resolution allows for exact discrimination between benign and malignant tumours, with a reported sensitivity of 84.21% and specificity of 99.3%. AI applications, such as convolutional neural networks, have the potential for diagnosis accuracy better than 97%. PET-based molecular imaging is critical for staging, detecting recurrences, and assessing therapy outcomes. FDA-approved tracers, such as FES-PET/CT, target oestrogen receptors and offer data for precision medicine. Emerging areas include PET/MRI integration and the application of artificial intelligence to increase diagnosis accuracy and enable personalized treatment options.

Conclusion

According to the literature, low-dose mammography is the only radiographic approach that has had a substantial influence on the diagnosis, staging, and patient follow-up for asymptomatic breast cancer screening. Mammography, or is the only precisely correct screening test for breast imaging. Though it is a useful screening tool, it has some limits, particularly in women with thick breasts. The latest evidence indicates that computer-aided detection, breast ultrasonography, and magnetic resonance imaging (MRI) are commonly used as adjuncts to mammography in modern clinical practice. These procedures improve the radiologist's ability to detect cancer and assess disease severity, which is essential for treatment planning and staging. Positron emission tomography, or PET, is also used to stage breast cancer and evaluate therapy outcomes. As imaging technology progresses, the role of imaging will change to reduce breast cancer morbidity and death. The progress in developing and commercializing the EIT breast imaging system will Support the dissemination of additional applications and infrastructure in line with EIT and similar depiction technologies. Currently, x-ray mammography is the most widely utilised breast-imaging technology, making it the “gold standard” in imaging-based breast examination.

Mammography is the standard for breast cancer screening because it is the only imaging modality to reduce mortality in large-scale studies, is highly prevalent, low cost, fairly quick, and sensitive to detection of early signs like microcalcifications. Other modalities like MRI, CT, and PET are less available, more costly, and better suited to diagnostic or high-risk conditions than population-wide screening. Digital Breast Tomosynthesis (3D mammography) improves detection in dense breasts, Contrast-Enhanced Mammography (CEM) offers functional imaging at no additional cost of MRI, Low-dose Molecular Imaging (e.g., PEM) offers high sensitivity without compression, AI-assisted screening improves accuracy, risk prediction, and workflow efficiency and Photoacoustic Imaging use ultrasound and light to offer functional imaging.

It would take a future replacement to be accurate, low in cost, scalable, and proven to reduce mortality.

Author contributions

ND: Writing – original draft. MS: Writing – review & editing. PY: Resources, Writing – original draft. RT: Resources, Validation, Writing – original draft.

Funding

The author(s) declared that financial support was not received for this work and/or its publication.

Conflict of interest

The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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The author(s) declared that generative AI was not used in the creation of this manuscript.

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References

1. Liu S, Wu G, Zhou C, Yan S, Cui H. The application of mammography imaging in the diagnosis and prediction of breast diseases. Prog Med Devices. (2024) 2:1–11. doi: 10.61189/295735bbiagx

Crossref Full Text | Google Scholar

2. Groheux D. FDG-PET/CT for primary staging and detection of recurrence of breast cancer. Semin Nucl Med. (2022) 52(5):508–19. doi: 10.1053/j.semnuclmed.2022.05.001

PubMed Abstract | Crossref Full Text | Google Scholar

3. Govorukhina VG, Semenov SS, Gelezhe PB, Didenko VV, Morozov SP, Andreychenko AE. The role of mammography in breast cancer radiomics. Digit Diagn. (2021) 2(2):185–99. doi: 10.17816/dd70479

Crossref Full Text | Google Scholar

4. Schoonjans JM, Brem RF. Fourteen-gauge ultrasonographically guided large-core needle biopsy of breast masses. J Ultrasound Med. (2001) 20(9):967–72. doi: 10.7863/jum.2001.20.9.967

PubMed Abstract | Crossref Full Text | Google Scholar

5. Lowes S, Leaver A, Redman A. Diagnostic and interventional imaging techniques in breast cancer. Surgery. (2019) 37(3):140–50. doi: 10.1016/j.mpsur.2019.01.011

Crossref Full Text | Google Scholar

6. Prasad SN, Houserkova D. The role of various modalities in breast imaging. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. (2007) 151(2):209–18. doi: 10.5507/bp.2007.036

PubMed Abstract | Crossref Full Text | Google Scholar

7. Lother D, Robert M, Elwood E, Smith S, Tunariu N, Johnston SRD, et al. Imaging in metastatic breast cancer, CT, PET/CT, MRI, WB-DWI, CCA: review and new perspectives. Cancer Imaging. (2023) 23(1):53. doi: 10.1186/s40644-023-00557-8

PubMed Abstract | Crossref Full Text | Google Scholar

8. Bhushan A, Gonsalves A, Menon JU. Current state of breast cancer diagnosis, treatment, and theranostics. Pharmaceutics. (2021) 13(5):723. doi: 10.3390/pharmaceutics13050723

PubMed Abstract | Crossref Full Text | Google Scholar

9. Grebić D, Valković-Zujić P, Pozderac I, Kustić D, Hrboka-Zekić M. Resonance imaging on the surgical management of newly diagnosed breast cancer. Libri Oncologici. (2022) 50(2–3):109–17. doi: 10.20471/lo.2022.50.02-03.17

Crossref Full Text | Google Scholar

10. Chung HL, Le-Petross HT, Leung JWT. Imaging updates to breast cancer lymph node management. Radiographics. (2021) 41(5):1283–99. doi: 10.1148/rg.2021210053

PubMed Abstract | Crossref Full Text | Google Scholar

11. Lima ZS, Ebadi MR, Amjad G, Younesi L. Application of imaging technologies in breast cancer detection: a review article. Open Access Maced J Med Sci. (2019) 7(5):838–48. doi: 10.3889/oamjms.2019.171

PubMed Abstract | Crossref Full Text | Google Scholar

12. Pomerantz BJ. Imaging and interventional radiology for cancer management. Surg Clin North Am. (2020) 100(3):499–506. doi: 10.1016/j.suc.2020.02.002

PubMed Abstract | Crossref Full Text | Google Scholar

13. Chala LF. Breast evaluation with imaging methods (n.d.).

Google Scholar

14. Thulkar S, Hari S. Present role of mammography/digital mammography in breast cancer management. PET Clin. (2009) 4(3):213–25. doi: 10.1016/j.cpet.2009.09.006

PubMed Abstract | Crossref Full Text | Google Scholar

15. Wang AT, Fan J, Van Houten HK, Tilburt JC, Stout NK, Montori VM, et al. Impact of the 2009 US preventive services task force guidelines on screening mammography rates on women in their 40s. PLoS One. (2014) 9(3):e91399. doi: 10.1371/journal.pone.0091399

PubMed Abstract | Crossref Full Text | Google Scholar

16. Bleyer A, Welch HG. Effect of three decades of screening mammography on breast-cancer incidence. N Engl J Med. (2012) 367(21):1998–2005. doi: 10.1056/NEJMoa1206809

PubMed Abstract | Crossref Full Text | Google Scholar

17. Mandelson MT, Oestreicher N, Porter PL, White D, Finder CA, Taplin SH, et al. Breast density as a predictor of mammographic detection: comparison of interval- and screen-detected cancers. J Natl Cancer Inst. (2000) 92(13):1081–7. doi: 10.1093/jnci/92.13.1081

PubMed Abstract | Crossref Full Text | Google Scholar

18. Kolb TM, Lichy J, Newhouse JH. Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: an analysis of 27,825 patient evaluations. Radiology. (2002) 225(1):165–75. doi: 10.1148/radiol.2251011667

PubMed Abstract | Crossref Full Text | Google Scholar

19. Mainiero MB, Lourenco A, Mahoney MC, Newell MS, Bailey L, Barke LD, et al. ACR appropriateness criteria breast cancer screening. J Am Coll Radiol. (2013) 10(1):11–4. doi: 10.1016/j.jacr.2012.09.036

PubMed Abstract | Crossref Full Text | Google Scholar

20. Berg WA, Zhang Z, Lehrer D, Jong RA, Pisano ED, Barr RG, et al. Detection of breast cancer with addition of annual screening ultrasound or a single screening MRI to mammography in women with elevated breast cancer risk. J Am Med Assoc. (2012) 307(13):1394–404. doi: 10.1001/jama.2012.388

PubMed Abstract | Crossref Full Text | Google Scholar

21. Berg WA. Supplemental screening sonography in dense breasts. Radiol Clin North Am. (2004) 42(5):845–51; vi. doi: 10.1016/j.rcl.2004.04.003

PubMed Abstract | Crossref Full Text | Google Scholar

22. Dan Q, Zheng T, Liu L, Sun D, Chen Y. Ultrasound for breast cancer screening in resource-limited settings: current practice and future directions. Cancers (Basel). (2023) 15(7):2112. doi: 10.3390/cancers15072112

PubMed Abstract | Crossref Full Text | Google Scholar

23. Feig S. Cost-effectiveness of mammography, MRI, and ultrasonography for breast cancer screening. Radiol Clin North Am. (2010) 48(5):879–91. doi: 10.1016/j.rcl.2010.06.002

PubMed Abstract | Crossref Full Text | Google Scholar

24. Warner E, Messersmith H, Causer P, Eisen A, Shumak R, Plewes D. Systematic review: using magnetic resonance imaging to screen women at high risk for breast cancer. Ann Intern Med. (2008) 148(9):671–9. doi: 10.7326/0003-4819-148-9-200805060-00007

PubMed Abstract | Crossref Full Text | Google Scholar

25. Saslow D, Boetes C, Burke W, Harms S, Leach MO, Lehman CD, et al. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin. (2007) 57(2):75–89. doi: 10.3322/canjclin.57.2.75

PubMed Abstract | Crossref Full Text | Google Scholar

26. Lee CH, Dershaw DD, Kopans D, Evans P, Monsees B, Monticciolo D, et al. Breast cancer screening with imaging: recommendations from the society of breast imaging and the ACR on the use of mammography, breast MRI, breast ultrasound, and other technologies for the detection of clinically occult breast cancer. J Am Coll Radiol. (2010) 7(1):18–27. doi: 10.1016/j.jacr.2009.09.022

PubMed Abstract | Crossref Full Text | Google Scholar

27. Sobue T. Screening for lung cancer with low-dose helical computed tomography: anti-lung cancer association project. J Clin Oncol. (2002) 20(4):911–20. doi: 10.1200/jco.20.4.911

PubMed Abstract | Crossref Full Text | Google Scholar

28. Schnitt SJ, Connolly JL, Khettry U, Mazoujian G, Brenner M, Silver B, et al. Pathologic findings on re-excision of the primary site in breast cancer patients considered for treatment by primary radiation therapy. Cancer. (1987) 59(4):675–81. doi: 10.1002/1097-0142(19870215)59:4%3C675::aid-cncr2820590402%3E3.0.co;2-u

PubMed Abstract | Crossref Full Text | Google Scholar

29. Loi A, Panjaitan RN, Siregar SD, Simarmata AM. Breast cancer classification through CT scan using convolutional neural network (CNN). Sinkron. (2024) 8(3):1551–7. doi: 10.33395/sinkron.v8i3.13706

Crossref Full Text | Google Scholar

30. Desperito E, Schwartz L, Capaccione KM, Collins BT, Jamabawalikar S, Peng B, et al. Chest CT for breast cancer diagnosis. Life (Basel, Switzerland). (2022) 12(11):1699. doi: 10.3390/life12111699

PubMed Abstract | Crossref Full Text | Google Scholar

31. Edmonds CE, O’Brien SR, McDonald ES, Mankoff DA, Pantel AR. PET imaging of breast cancer: current applications and future directions. J Breast Imaging. (2024) 6(6):586–600. doi: 10.1093/jbi/wbae053

PubMed Abstract | Crossref Full Text | Google Scholar

32. Katal S, McKay MJ, Taubman K. PET molecular imaging in breast cancer: current applications and future perspectives. J Clin Med. (2024) 13(12):3459. doi: 10.3390/jcm13123459

PubMed Abstract | Crossref Full Text | Google Scholar

Keywords: cancer, CECT, magnetic resonance mammography, breast, mammography, contrast

Citation: Dagar N, Sarin M, Yadav P and Thidwar R (2026) Radiologic imaging and its current importance in breast cancer management. Front. Radiol. 5:1689635. doi: 10.3389/fradi.2025.1689635

Received: 20 August 2025; Revised: 28 October 2025;
Accepted: 30 November 2025;
Published: 27 January 2026.

Edited by:

Salah D. Qanadli, Swiss Institute of Image-Guided Therapies, Switzerland

Reviewed by:

Hussein Elaibi, Dumlupinar University, Türkiye

Copyright: © 2026 Dagar, Sarin, Yadav and Thidwar. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Monu Sarin, bW9udV9mbWhzQHNndHVuaXZlcnNpdHkub3Jn

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.