CASE REPORT article
Front. Radiol.
Sec. Interventional Radiology
Volume 5 - 2025 | doi: 10.3389/fradi.2025.1694006
Case Report: Ultrasound-Guided Fine-Needle Aspiration for Parathyroid Cyst
Provisionally accepted
Alessandro Serblin1*
Roberto Valcavi2*- 1Universita degli Studi di Ferrara, Ferrara, Italy
- 2ETC - The Endocrine & Thyroid Clinic, Reggio Emilia, Italy
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Abstract: A 55-year-old man was referred to our Department with a cystic lesion in the lower right lobe of the thyroid, incidentally discovered on ultrasound. The mass measured 52.1 x 55.3 x 66.8 mm, with a volume of 93.2 mL, and caused significant tracheal indentation with contralateral deviation. The patient was asymptomatic and did not have dysphagia, hoarseness or dyspnoea. Ultrasound-guided fine-needle aspiration of the lesion yielded a clear, "rock-water" fluid. Biochemical analysis of the aspirate revealed elevated parathyroid hormone (PTH), leading to a diagnosis of a parathyroid cyst (PCs). This case highlights the importance of considering PCs in the differential diagnosis of large cystic neck masses, particularly when they mimic thyroid nodules. We report on this case and discuss the diagnostic challenges and management strategies for this rare condition.
Keywords: Parathyroid Cysts (PCs), Cystic thyroid nodule, parathyroid hormone (PTH), Fine-needle aspiration (FNA), Thyroid ultrasound (US)
Received: 27 Aug 2025; Accepted: 09 Oct 2025.
Copyright: © 2025 Serblin and Valcavi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Alessandro Serblin, dott.alessandroserblin@gmail.com
Roberto Valcavi, roberto.valcavi@gmail.com
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