Your new experience awaits. Try the new design now and help us make it even better

ORIGINAL RESEARCH article

Front. Radiol.

Sec. Artificial Intelligence in Radiology

This article is part of the Research TopicTransforming medical imaging with advanced deep learning techniquesView all 6 articles

The application of deep neural networks to the detection of lumbar hernias: results from the approaches based on convolutional networks and transformers

Provisionally accepted
António  FernandesAntónio Fernandes1*João  RodriguezJoão Rodriguez1Susana  MoleirinhoSusana Moleirinho1Irina  TrofimenkoIrina Trofimenko1Ekaterina  GusevaEkaterina Guseva1Alexander  MartinovichAlexander Martinovich1Ilzane  MoraisIlzane Morais1Louise  BisoloLouise Bisolo1Luis  Mendes GomesLuis Mendes Gomes2*José  MachadoJosé Machado3
  • 1SliceD Group Research Center, Lisbon, Portugal
  • 2University of the Azores, Ponta Delgada, Portugal
  • 3Universidade do Minho, Braga, Portugal

The final, formatted version of the article will be published soon.

ABSTRACT Background: The increasing demand for lumbar spine MRI exams, combined with radiologist shortages, has underscored the need for automated tools to assist in diagnosing degenerative spinal conditions. Despite the proliferation of AI tools in radiology, no CE or FDA-approved applications currently focus on pathologies in the lumbar spine. This study aimed to develop a pipeline for automatic identification of intervertebral disc herniation, contributing to more efficient clinical decision-making. Methods: A dataset of 484 lumbar spine MRI examinations acquired from four manufacturers was used to develop a multi-stage deep learning pipeline. A subset of 165 studies (5,200 sagittal slices) was manually annotated by radiologists and used for training and validation of vertebrae and intervertebral disc segmentation models, including U-Net, DeepLabV3+, and MA-Net with EfficientNet-B2 backbones. Anatomically informed post-processing was applied to assign disc-level labels and extract disc-centered volumes. Disc-level binary classification (herniated vs. non-herniated) was then performed using 3D patch-based models, including ResNet, SENet, EfficientNet-B2, and Vision Transformer (ViT) architectures, with all dataset splits performed at the patient level. Results: The best segmentation performance was achieved by MA-Net with EfficientNet-B2, yielding a Dice Score of 0.898 for three-class segmentation (background, vertebrae, discs). For classification, the evaluated models achieved F1-scores between 0.66 and 0.73. The best performance was obtained with a ResNet18-based model, indicating that once anatomical localization and disc extraction are addressed by the segmentation stage, lower-capacity architectures can be effective for binary classification. The simplified three-class segmentation improved model robustness, and post-processing enabled disc-level precision essential for downstream classification, which achieved consistent performance across models under the available data regime. Conclusion: The proposed AI pipeline successfully automates the identification of lumbar disc herniation in MRI exams. This approach has the potential to enhance diagnostic efficiency, reduce radiologist workload, and improve reproducibility in identifying disc pathologies. While limited by sample size and class imbalance, the methodology lays a strong foundation for scalable annotation and integration of AI in routine spinal diagnostics.

Keywords: 3D Classification Models, deep learning, Disc herniation, Lumbar spine MRI, Medical image segmentation, Radiology Automation

Received: 10 Oct 2025; Accepted: 02 Feb 2026.

Copyright: © 2026 Fernandes, Rodriguez, Moleirinho, Trofimenko, Guseva, Martinovich, Morais, Bisolo, Mendes Gomes and Machado. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
António Fernandes
Luis Mendes Gomes

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.