Debates in Assisted Reproduction: Male Fertility

Over the past three decades, assisted reproductive treatments for infertility have become a regular practice. The introduction of new treatments for male infertility often leads to debates amongst the scientific community, for example how such treatments should be performed for the management of fertility in various situations.

This Research Topic of Frontiers in Reproductive Health wishes to foster debate and discussion in the community with pros and cons on the following topics:

• Is it better to use ejaculated or testicular sperm in men with high rates of DNA fragmentation?
• In Klinefelter syndrome patients with non-obstructive azoospermia, does the use of a high dosage of gonadotropins increase sperm retrieval rates?
• Are there other ways to retrieve testicular sperm other than testicular microdissection?
• Is PESA (Percutaneous epididymal sperm aspiration) or MESA (Microsurgical epididymal sperm aspiration) the preferred retrieval method for epididymal sperm?
• In men with varicocele and non-obstructive azoospermia, should we use intracytoplasmic sperm injection (ICSI) or varicocelectomy plus intracytoplasmic sperm injection (ICSI)?
• Is there a role for Clomifene treatment for men with idiopathic oligospermia? Or should treatments start with assisted reproduction technologies?
• For men with criptozoospermia, is it better to use ejaculated or testicular sperm when performing intracytoplasmic sperm injection (ICSI)?

Alongside opinion or perspective pieces, this Research Topic welcomes original research and review articles on the above themes.

Keywords: male fertility, infertility, assisted reproduction, treatment, management, sperm

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.