Insights into Dosimetry and Investigation of Dose Effects in Molecular Radiotherapy (MRT)

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Background

Molecular radiotherapy (MRT) is a rapidly growing field of minimally invasive cancer treatment within nuclear medicine. In recent years, its application, especially in prostate cancer therapy, has expanded significantly. However, depending on the type of MRT, our understanding of dose effects on tumours and at-risk organs remains limited, hindering the further optimization of treatments through personalized dosing.

Personalized dosimetry holds the potential to tailor treatments to individual patients, maximizing therapeutic efficacy while minimizing side effects. Therefore, this Research Topic aims to gather the latest research on personalized dosimetry and dose-effect relationships, both from clinical trials and foundational studies. By focusing on these areas, we hope to advance the development of dosimetry methods and improve the efficacy of MRT through individualized treatment approaches, contributing to the ongoing evolution of precision medicine in radionuclide therapy.

In this Research Topic, we aim to showcase the latest research advancements in MRT. Our focus is on highlighting progress in evaluating dose-effect relationships, a key factor in optimizing treatment outcomes. By gathering studies from across the field, we hope to provide insights into how various factors impact the therapeutic effects of MRT at different doses. Additionally, we aim to spotlight innovative approaches to personalized dosimetry, a rapidly growing area of research.

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Keywords: Radionuclide Therapy, Radiopeptide Therapy, Dosimetry, Personalized Dosing, Dose-Effect Relationship, Time-Activity Curve, Therapy Response, MRT

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