Pharmacodynamic and Pharmacokinetic Aspects of Redox Signaling in Inflammation-associated Damage and Diseases

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Background

The intricate interplay between redox signaling and inflammation lies at the core of numerous pathologies, ranging from chronic inflammatory disorders to acute tissue damage. This call for papers seeks to delve into the multifaceted relationship between redox signaling and inflammation associated diseases, with a particular focus on metabolic diseases.

Research in this area may encompass investigations into the molecular mechanisms underlying redox signaling pathways in inflammation-induced damage and diseases. Contributions are encouraged to explore the role of oxidative stress, antioxidant defenses, and redox-regulated pathways in modulating inflammatory responses and disease progression.

Furthermore, this call invites studies that elucidate the pharmacokinetic profiles of various therapeutic agents targeting redox signaling pathways in the context of inflammation-associated diseases. Insights into drug metabolism, distribution, and elimination kinetics are crucial for optimizing therapeutic interventions and improving clinical outcomes.

Submissions may include original research articles, reviews, and methodological studies that advance our understanding of redox signaling in inflammation-related pathologies and provide insights into the pharmacokinetics of pharmacological interventions in metabolic diseases. Contributions from interdisciplinary approaches integrating biochemistry, pharmacology, immunology, and clinical research are highly encouraged.

Authors are invited to contribute their expertise to this thematic issue, aiming to expand our knowledge of redox signaling mechanisms in inflammation-associated damage and diseases, and to foster the development of novel therapeutic strategies with improved pharmacokinetic properties.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

  • Brief Research Report
  • Case Report
  • Clinical Trial
  • Data Report
  • Editorial
  • FAIR² Data
  • General Commentary
  • Hypothesis and Theory
  • Methods

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Keywords: pharmacodynamics, Pharmacokinetics, Reactive Oxygen Species (ROS), Oxidative Stress, Inflammatory Mediators, Transcription Factors (e.g., Absorption, Bioavailability, Metabolic Enzymes (e.g., Lipid Peroxidation

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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