Aprepitant | List of Frontiers open access articles

Original Research

Published on 11 Jan 2022

Aprepitant Inhibits JNK and p38/MAPK to Attenuate Inflammation and Suppresses Inflammatory Pain

in Neuropharmacology

Yang Yang
Wei Zhou
Xiuqi Xu
Xianxiu Ge
Fei Wang
Guang-Qin Zhang
Lin Miao
Xueting Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2021.811584

9,753 views
44 citations

Systematic Review

Published on 25 Aug 2021

Cost-Effectiveness of Aprepitant in Preventing Chemotherapy-Induced Nausea and Vomiting: A Systematic Review of Published Articles

in Health Economics

Tingting Qiu
Peng Men
Tong Sun
Suodi Zhai

Frontiers in Public Health

doi 10.3389/fpubh.2021.660514

7,831 views
9 citations

Original Research

Published on 08 Sep 2023

Effects of aprepitant on post-operative nausea and vomiting in patients with congenital heart disease undergoing cardiac surgery or catheterization procedures: a retrospective study with subjects as their own historical control

in Cardiothoracic Anesthesiology

John W. Belk
Mark D. Twite
Katherine S. Klockau
Lori J. Silveira
Rachel G. Clopton

Frontiers in Anesthesiology

doi 10.3389/fanes.2023.1190383

3,336 views
1 citation

Original Research

Published on 05 Jul 2023

Comprehensive analysis of the progression mechanisms of CRPC and its inhibitor discovery based on machine learning algorithms

in Cancer Genetics and Oncogenomics

Zhen Wang
Jing Zou
Le Zhang
Hongru Liu
Bei Jiang
Yi Liang
Yuzhe Zhang

Frontiers in Genetics

doi 10.3389/fgene.2023.1184704

9,312 views
7 citations

Original Research

Published on 17 Feb 2025

Enhanced efficacy of aprepitant-based triple prophylaxis in preventing postoperative nausea and vomiting following metabolic bariatric surgery: a single-center, retrospective cohort study

in Intensive Care Medicine and Anesthesiology

Xiaodong Shan
Yidi Yang
Xiaoao Xiao
Mingchuang Zhang
Rui Chen
Qingqiu Huang
Yuanqing Gao
Xitai Sun

Frontiers in Medicine

doi 10.3389/fmed.2025.1481720

2,998 views

Clinical Trial

Published on 05 Jul 2016

A Prospective, Randomized, Double-Blinded, Double-Dummy Pilot Study to Assess the Preemptive Effect of Triple Therapy with Aprepitant, Dexamethasone, and Promethazine versus Ondansetron, Dexamethasone and Promethazine on Reducing the Incidence of Postoperative Nausea and Vomiting Experienced by Patients Undergoing Craniotomy Under General Anesthesia

in Intensive Care Medicine and Anesthesiology

Sergio Daniel Bergese
Erika G. Puente
Maria A. Antor
Adolfo L. Viloria
Vedat Yildiz
Nicolas Alexander Kumar
Alberto A. Uribe

Frontiers in Medicine

doi 10.3389/fmed.2016.00029

7,568 views
32 citations

Review

Published on 24 Aug 2021

New Developments in Prokinetic Therapy for Gastric Motility Disorders

in Gastrointestinal and Hepatic Pharmacology

Michael Camilleri
Jessica Atieh

Frontiers in Pharmacology

doi 10.3389/fphar.2021.711500

105,284 views
93 citations

Original Research

Published on 04 Jan 2023

Potential therapeutic effect of NK1R antagonist in diabetic non-healing wound and depression

in Diabetes: Molecular Mechanisms

Mingyu Li
Hao Ma
Shunuo Zhang
Yuan Peng
Liang Ding
Yixin Zhang
Peiru Min

Frontiers in Endocrinology

doi 10.3389/fendo.2022.1077514

4,922 views
8 citations

Review

Published on 30 Jan 2017

Delayed Chemotherapy-Induced Nausea and Vomiting: Pathogenesis, Incidence, and Current Management

in Pharmacology of Anti-Cancer Drugs

Bernardo L. Rapoport

Frontiers in Pharmacology

doi 10.3389/fphar.2017.00019

42,246 views
100 citations

Original Research

Published on 26 Mar 2026

Neuropeptide and cytokines expression in long COVID-19 related neuropsychological sequelae: insights into NK1R-mediated neuroinflammation and in silico therapeutic targeting

in Cellular Neuropathology

Muhammad Abdullah
Anam Naz
Leah R. Reznikov
Javed Anver Qureshi
Ammarah Hasnain
Ayesha Obaid
Amjed Ali

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2026.1763029

605 views

Mini Review

Published on 16 Jul 2025

Trigeminal nerve-driven neurogenic inflammation linking migraine to glioblastoma invasion: a literature review

in Cancer Immunity and Immunotherapy

Xiaoli Song
Qian Zhu
Jieying Zhang
Jin Yang
Xinxin Zhang
Qian Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1632154

6,170 views
2 citations

Original Research

Published on 08 Jul 2022

The Clinical Observation of Acupuncture Combined With Antiemetic Drugs in the Prevention and Treatment of CINV in Breast Cancer Patients

in Breast Cancer

Fanming Kong
Ziwei Wang
Na Wang
Lu Zhao
Qingyun Mei
Yongchao Yu
Dou Zhang
Xiaojiang Li
Yingjie Jia

Frontiers in Oncology

doi 10.3389/fonc.2022.888651

8,076 views
14 citations

Original Research

Published on 22 Apr 2021

Involvement of 5-Serotonin and Substance p Pathways in Dichroa Alkali Salt-Induced Acute Pica in Rats

in Ethnopharmacology

Lina Ma
Sidi Li
Jian Li
Guangping Zhang
Hongping Hou
Zuguang Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2021.588837

7,052 views
2 citations

Original Research

Published on 31 Jul 2024

Safety assessment of neurokinin-1 receptor antagonist: real-world adverse event analysis from the FAERS database

in Drugs Outcomes Research and Policies

Chuanli Yang
Pengyang Xu
Teng Wu
Yunhe Fan
Qingqing Li
Jijun Zhang
Xiaobing Shen
Xiushan Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1413709

5,863 views
5 citations

Original Research

Published on 27 Jan 2025

Effect of drug interactions with apixaban on clinical outcomes in cancer patients with venous thromboembolism

in Cardio-Oncology

Marte Svalastoga
Trine-Lise Larsen
Jorunn Brekke
Tone Enden
Hege Frøen
Herish Garresori
Eva Marie Jacobsen
Alina Carmen Porojnicu
Anne Hansen Ree
Dag Torfoss

Frontiers in Oncology

doi 10.3389/fonc.2025.1520725

3,479 views

Original Research

Accepted on 17 Apr 2026

The Impact of NK1 Receptor Antagonist Selection on Chemotherapy-related Adverse Events: A Retrospective Study of Adverse Events in Paclitaxel or Nab-paclitaxel and Carboplatin Combination Therapy with Fosnetupitant and Aprepitant Use

in Pharmacology of Anti-Cancer Drugs

Kenta Yamaoka
Saki Kajita
Manabu Kume
Masaki Hirabatake
Yuki Sato
Tohru Hashida
Ryo Tachikawa
Nobuyuki Muroi

Frontiers in Pharmacology