Cavd | List of Frontiers open access articles

Mini Review

Published on 11 Jun 2021

Label-Free Multiphoton Microscopy for the Detection and Monitoring of Calcific Aortic Valve Disease

in Heart Valve Disease

Ishita Tandon
Kyle P. Quinn
Kartik Balachandran

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.688513

5,544 views
6 citations

Original Research

Published on 26 Sep 2024

Higher serum phosphate within the normal range is associated with the development of calcified aortic valve disease

in Heart Valve Disease

Kyung An Kim
Hae-Ok Jung
Mi-Jeong Kim
So-Young Lee
Yuran Ahn
Mi-Hyang Jung
Woo-Baek Chung
Dong-Hyeon Lee
Ho-Joong Youn
Hyuk-Jae Chang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1450757

2,129 views
2 citations

Review

Published on 23 Dec 2021

Pathogenesis and Molecular Immune Mechanism of Calcified Aortic Valve Disease

in Cardiovascular Biologics and Regenerative Medicine

Weikang Bian
Zhicheng Wang
Chongxiu Sun
Dai-Min Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.765419

7,622 views
29 citations

Original Research

Published on 09 Nov 2022

Congenital absence of the vas deferens with hypospadias or without hypospadias: Phenotypic findings and genetic considerations

in Human and Medical Genomics

Jianzheng Fang
Xiaoyi Wang
Xueping Sun
Yugui Cui
Feiyang Diao
Xiaoyu Yang

Frontiers in Genetics

doi 10.3389/fgene.2022.1035468

4,850 views
4 citations

Original Research

Published on 13 Oct 2022

Integrated proteomic and metabolomic profile analyses of cardiac valves revealed molecular mechanisms and targets in calcific aortic valve disease

in Heart Valve Disease

Bo Fu
Jing Wang
Lianqun Wang
Qiang Wang
Zhigang Guo
Meilin Xu
Nan Jiang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2022.944521

6,611 views
12 citations

Original Research

Published on 04 Jan 2023

Shared gene characteristics and molecular mechanisms of macrophages M1 polarization in calcified aortic valve disease

in Heart Valve Disease

Ming Qin
Qian Chen
Ning Li
Xiangyang Xu
Chuyi Wang
Guokun Wang
Zhiyun Xu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2022.1058274

3,595 views
1 citation

Original Research

Published on 12 Aug 2025

Trends in the global burden of aortic valve calcification disease in the working-age population from 1992 to 2021

in Cardiovascular Epidemiology and Prevention

Songzhe Wu
Weiguang Yang
Yixin Li
Tao Wei
Yaodong Sun
Lin Xia
Yan Zhu
Naishi Wu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1544273

2,712 views

Review

Published on 06 Nov 2025

Insights into preclinical models of calcific aortic valve disease and their translational potential

in Atherosclerosis and Vascular Medicine

Isabelle Lafosse
Romuald Mentaverri
Carine Avondo
Youssef Bennis
Christophe Tribouilloy
Lucie Hénaut

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1621990

1,758 views

Original Research

Published on 29 Apr 2022

The Natural Product Andrographolide Ameliorates Calcific Aortic Valve Disease by Regulating the Proliferation of Valve Interstitial Cells via the MAPK-ERK Pathway

in Experimental Pharmacology and Drug Discovery

Yuming Huang
Ming Liu
Chungeng Liu
Nianguo Dong
Liang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.871748

6,086 views
14 citations

Review

Published on 27 Jan 2022

Lipoprotein(a), a Lethal Player in Calcific Aortic Valve Disease

in Molecular and Cellular Pathology

Jiahui Hu
Hao Lei
Leiling Liu
Danyan Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.812368

9,364 views
21 citations

Original Research

Published on 15 Dec 2022

Potential biomarkers and immune cell infiltration involved in aortic valve calcification identified through integrated bioinformatics analysis

in Vascular Physiology

Xiaoshuo Lv
Xiaohui Wang
Jingwen Liu
Feng Wang
Mingsheng Sun
Xueqiang Fan
Zhidong Ye
Peng Liu
Jianyan Wen

Frontiers in Physiology

doi 10.3389/fphys.2022.944551

5,160 views
6 citations

Original Research

Published on 19 Dec 2024

Identification and validation of the diagnostic biomarker MFAP5 for CAVD with type 2 diabetes by bioinformatics analysis

in Inflammation

Qiang Shen
Lin Fan
Chen Jiang
Dingyi Yao
Xingyu Qian
Fuqiang Tong
Zhengfeng Fan
Zongtao Liu
Nianguo Dong
Chao Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1506663

8,000 views
1 citation

Original Research

Published on 08 Oct 2025

Integrating bioinformatics and machine learning analyses to identify immune-related secretory proteins and therapeutic small-molecule drugs in calcific aortic valve disease with type 2 diabetes

in Molecular Innate Immunity

Xiang Zhang
Jiahui Wang
Qian Hu
Bangyu Guo
Mengjie Hu
Xiaobo Yu
Shunbo Wei
Qiujie Luo
Yuqing Zhang
Shentao Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634655

2,559 views

Review

Published on 28 Apr 2025

Diabetes and calcific aortic valve disease: implications of glucose-lowering medication as potential therapy

in Cardiovascular and Smooth Muscle Pharmacology

Feng Liu
Haipeng Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583267

3,802 views
3 citations

Review

Published on 09 Jan 2026

The role of microRNAs in calcific aortic valve disease

in Heart Valve Disease

Yi-Zhou Peng
Yang He
Yue-Jiao Yang
Liang Tang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1637753

898 views

Original Research

Published on 29 Sep 2022

Crenigacestat (LY3039478) inhibits osteogenic differentiation of human valve interstitial cells from patients with aortic valve calcification in vitro

in Heart Valve Disease

Arseniy A. Lobov
Nadezhda V. Boyarskaya
Olga S. Kachanova
Ekaterina S. Gromova
Anastassia A. Shishkova
Bozhana R. Zainullina
Alexander S. Pishchugin
Alexey A. Filippov
Vladimir E. Uspensky
Anna B. Malashicheva

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2022.969096

4,075 views
11 citations

Articles

Label-Free Multiphoton Microscopy for the Detection and Monitoring of Calcific Aortic Valve Disease

Higher serum phosphate within the normal range is associated with the development of calcified aortic valve disease

Pathogenesis and Molecular Immune Mechanism of Calcified Aortic Valve Disease

Congenital absence of the vas deferens with hypospadias or without hypospadias: Phenotypic findings and genetic considerations

Integrated proteomic and metabolomic profile analyses of cardiac valves revealed molecular mechanisms and targets in calcific aortic valve disease

Shared gene characteristics and molecular mechanisms of macrophages M1 polarization in calcified aortic valve disease

Trends in the global burden of aortic valve calcification disease in the working-age population from 1992 to 2021

Insights into preclinical models of calcific aortic valve disease and their translational potential

The Natural Product Andrographolide Ameliorates Calcific Aortic Valve Disease by Regulating the Proliferation of Valve Interstitial Cells via the MAPK-ERK Pathway

Lipoprotein(a), a Lethal Player in Calcific Aortic Valve Disease

Potential biomarkers and immune cell infiltration involved in aortic valve calcification identified through integrated bioinformatics analysis

Identification and validation of the diagnostic biomarker MFAP5 for CAVD with type 2 diabetes by bioinformatics analysis

Integrating bioinformatics and machine learning analyses to identify immune-related secretory proteins and therapeutic small-molecule drugs in calcific aortic valve disease with type 2 diabetes

Diabetes and calcific aortic valve disease: implications of glucose-lowering medication as potential therapy

The role of microRNAs in calcific aortic valve disease

Crenigacestat (LY3039478) inhibits osteogenic differentiation of human valve interstitial cells from patients with aortic valve calcification in vitro