Cgassting | List of Frontiers open access articles

Review

Published on 22 Dec 2022

Research advances in cGAS–stimulator of interferon genes pathway and central nervous system diseases: Focus on new therapeutic approaches

in Molecular Signalling and Pathways

Jiao Ding
Yijie Dai
Jiahui Zhu
Xuemei Fan
Hao Zhang
Bo Tang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.1050837

7,869 views
10 citations

Original Research

Published on 25 Nov 2025

Integrative modeling of FOXO-mediated autophagy in NSCLC: linking cGAS–STING signaling to IL-6 dynamics

in Molecular and Cellular Oncology

Divya Rani
Shweta Khandibharad
Shailza Singh

Frontiers in Oncology

doi 10.3389/fonc.2025.1689137

1,699 views

Review

Published on 03 Dec 2025

Recent advances in targeting the cGAS–STING pathway for immunotherapy in orthopedic diseases

in Cancer Immunity and Immunotherapy

Feipeng Wu
Shan Hui
Dapeng Li
Guoqing Pan
Wenchao Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726423

3,134 views
1 citation

Original Research

Published on 04 Feb 2026

UNC93B1 promotes pancreatic cancer progression through modulation of cGAS–STING signaling

in Cancer Immunity and Immunotherapy

Hao Yang
Yukun Li
Jing Su
Haiyan Zhang
Wenxin Zhu
Kanger Shen
Wei Xu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1718849

711 views

Review

Accepted on 30 Jan 2026

Bridging Innate Immunity and Iron-Dependent Death: The Interplay Between Cyclic GMP–AMP Synthase–Stimulator of Interferon Genes Nexus and Ferroptosis in Cancer and Inflammation

in Cell Death and Survival

Yun-qing Hou
Xin-xin Chen
Xin-xu Chen
Xiang Wang

Frontiers in Cell and Developmental Biology

164 views

Original Research

Published on 14 Jun 2018

The cGas–Sting Signaling Pathway Is Required for the Innate Immune Response Against Ectromelia Virus

in Viral Immunology

Wen-Yu Cheng
Xiao-Bing He
Huai-Jie Jia
Guo-Hua Chen
Qi-Wang Jin
Zhao-Lin Long
Zhi-Zhong Jing

Frontiers in Immunology

doi 10.3389/fimmu.2018.01297

22,279 views
64 citations

Review

Published on 18 Feb 2026

Combining advanced radiotherapy techniques and immunotherapy: immunomodulatory mechanisms and clinical prospects

in Cancer Immunity and Immunotherapy

Linsen Zhou
Qianyi Liu
Yongze He
Ying Tang
Shuotong Liu
Xiaobin Wang
Shiyan Shen
Jialin Ji
Zhen Liu
Xianhu Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2026.1737661

1,047 views

Mini Review

Published on 29 Nov 2021

Crosstalk Between Autophagy and the cGAS–STING Signaling Pathway in Type I Interferon Production

in Cell Death and Survival

Kunli Zhang
Sutian Wang
Hongchao Gou
Jianfeng Zhang
Chunling Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.748485

14,559 views
44 citations

Mini Review

Published on 21 Sep 2023

cGAS–STING pathway in ischemia-reperfusion injury: a potential target to improve transplantation outcomes

in Alloimmunity and Transplantation

Zijian Chen
Yangqi Liu
Zeying Lin
Weizhe Huang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1231057

6,370 views
3 citations

Original Research

Published on 08 Jan 2021

Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway

in Molecular and Cellular Oncology

Yuan Qiao
Shan Zhu
Shuanglin Deng
Shan-Shan Zou
Bao Gao
Guoxia Zang
Jing Wu
Yuxue Jiang
Yong-Jun Liu
Jingtao Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2020.606001

19,307 views
39 citations

Original Research

Published on 27 Feb 2026

Integrative pan-cancer analysis reveals AARS2 as a lactylation-associated biomarker and therapeutic target in colon adenocarcinoma

in Cancer Immunity and Immunotherapy

Mingyang Zou
Zixuan Ding
Yifan Fu
Wenxin Yu
Yulan Song
Xinyue Wu
Yixin Pan
Shaobo Wu
Jiebin Pan

Frontiers in Immunology

doi 10.3389/fimmu.2026.1732811

126 views

Mini Review

Published on 09 Apr 2018

Targeting Cytosolic Nucleic Acid-Sensing Pathways for Cancer Immunotherapies

in Molecular Innate Immunity

Sandra Iurescia
Daniela Fioretti
Monica Rinaldi

Frontiers in Immunology

doi 10.3389/fimmu.2018.00711

23,802 views
117 citations

Review

Published on 06 Aug 2025

Is postoperative cognitive dysfunction a disease of microglial inflammatory memory? A state-transition model from metabolic stress to epigenetic lock-in

in Brain Disease Mechanisms

Xiangyu Wu
Tingye He
Fei He
Li Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1648161

4,458 views
5 citations

Perspective

Published on 10 Dec 2025

Oncolytic virus therapy for osteosarcoma: mechanisms, opportunities, and challenges

in Cancer Immunity and Immunotherapy

Jia-Wen Wang
Xiaolei Ge
Jia-Hui Liu
Xiaoyu Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724768

1,814 views

Perspective

Published on 08 Oct 2025

Oncolytic virus therapy in the elderly: immune frailty, challenges, and perspectives

in Cancer Immunity and Immunotherapy

Jia-Wen Wang
Jia-Hui Liu
Yue-Lin Liu
Wen-Zheng Xu
Zi-Bo Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686659

3,068 views
2 citations

Original Research

Published on 03 Nov 2025

Lily polysaccharides alleviate colitis through the microbiota–N8-acetylspermidine–cGAS–STING signaling axis

in Microorganisms in Vertebrate Digestive Systems

Yuanyu Wu
Xiaoyu Wan
Lu Hou
Haolong Zhang
Jialin Wang
Kun Wu
Junwei Shao
Zheyu Song

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1686902

2,404 views

Articles

Research advances in cGAS–stimulator of interferon genes pathway and central nervous system diseases: Focus on new therapeutic approaches

Integrative modeling of FOXO-mediated autophagy in NSCLC: linking cGAS–STING signaling to IL-6 dynamics

Recent advances in targeting the cGAS–STING pathway for immunotherapy in orthopedic diseases

UNC93B1 promotes pancreatic cancer progression through modulation of cGAS–STING signaling

Bridging Innate Immunity and Iron-Dependent Death: The Interplay Between Cyclic GMP–AMP Synthase–Stimulator of Interferon Genes Nexus and Ferroptosis in Cancer and Inflammation

The cGas–Sting Signaling Pathway Is Required for the Innate Immune Response Against Ectromelia Virus

Combining advanced radiotherapy techniques and immunotherapy: immunomodulatory mechanisms and clinical prospects

Crosstalk Between Autophagy and the cGAS–STING Signaling Pathway in Type I Interferon Production

cGAS–STING pathway in ischemia-reperfusion injury: a potential target to improve transplantation outcomes

Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway

Integrative pan-cancer analysis reveals AARS2 as a lactylation-associated biomarker and therapeutic target in colon adenocarcinoma

Targeting Cytosolic Nucleic Acid-Sensing Pathways for Cancer Immunotherapies

Is postoperative cognitive dysfunction a disease of microglial inflammatory memory? A state-transition model from metabolic stress to epigenetic lock-in

Oncolytic virus therapy for osteosarcoma: mechanisms, opportunities, and challenges

Oncolytic virus therapy in the elderly: immune frailty, challenges, and perspectives

Lily polysaccharides alleviate colitis through the microbiota–N8-acetylspermidine–cGAS–STING signaling axis