Chemical Chaperones | List of Frontiers open access articles

Brief Research Report

Published on 24 Sep 2025

Exploring the binding sites of VRT534 at Cx26 as a putative chemical chaperone for targeted treatment of hereditary hearing disorders

in Precision Medicine

Jennifer Harre
Dahua Wang
Athanasia Warnecke
Carsten Zeilinger

Frontiers in Medicine

doi 10.3389/fmed.2025.1607598

1,315 views

Review

Published on 23 Sep 2020

Proteostasis Regulation in the Endoplasmic Reticulum: An Emerging Theme in the Molecular Pathology and Therapeutic Management of Familial Hypercholesterolemia

in Genetics of Common and Rare Diseases

Deepu Oommen
Praseetha Kizhakkedath
Aseel A. Jawabri
Divya Saro Varghese
Bassam R. Ali

Frontiers in Genetics

doi 10.3389/fgene.2020.570355

9,074 views
11 citations

Review

Published on 02 Apr 2019

The Roles of Cholesterol and Its Metabolites in Normal and Malignant Hematopoiesis

in Cancer Endocrinology

Hideyuki Oguro

Frontiers in Endocrinology

doi 10.3389/fendo.2019.00204

18,714 views
61 citations

Hypothesis and Theory

Published on 28 Aug 2018

Osmolyte Induced Tumorigenesis and Metastasis: Interactions With Intrinsically Disordered Proteins

in Cancer Molecular Targets and Therapeutics

Franklin D. Rumjanek

Frontiers in Oncology

doi 10.3389/fonc.2018.00353

3,891 views
7 citations

Original Research

Published on 06 Feb 2018

Functional G-Protein-Coupled Receptor (GPCR) Synthesis: The Pharmacological Analysis of Human Histamine H1 Receptor (HRH1) Synthesized by a Wheat Germ Cell-Free Protein Synthesis System Combined with Asolectin Glycerosomes

in Experimental Pharmacology and Drug Discovery

Yasuyuki Suzuki
Tomio Ogasawara
Yuki Tanaka
Hiroyuki Takeda
Tatsuya Sawasaki
Masaki Mogi
Shuang Liu
Kazutaka Maeyama

Frontiers in Pharmacology

doi 10.3389/fphar.2018.00038

12,243 views
23 citations

Review

Published on 06 Jan 2026

Modulation of endoplasmic reticulum stress–induced insulin resistance by the low-carbohydrate high-fat ketogenic diet

in Nutrition and Metabolism

Basmah M. Eldakhakhny
Fatma M. Ghoneim
Yousef M. Almoghrabi
Ghada Ajabnoor
Faisal Alandejani
Salwa M. Abo El-Khair
Salma A. Elsamanoudy
Taghreed Shamrani
Moaaz A. Siddiqui
Ayman Z. Elsamanoudy

Frontiers in Nutrition

doi 10.3389/fnut.2025.1704597

1,343 views

Articles

Exploring the binding sites of VRT534 at Cx26 as a putative chemical chaperone for targeted treatment of hereditary hearing disorders

Proteostasis Regulation in the Endoplasmic Reticulum: An Emerging Theme in the Molecular Pathology and Therapeutic Management of Familial Hypercholesterolemia

The Roles of Cholesterol and Its Metabolites in Normal and Malignant Hematopoiesis

Osmolyte Induced Tumorigenesis and Metastasis: Interactions With Intrinsically Disordered Proteins

Functional G-Protein-Coupled Receptor (GPCR) Synthesis: The Pharmacological Analysis of Human Histamine H1 Receptor (HRH1) Synthesized by a Wheat Germ Cell-Free Protein Synthesis System Combined with Asolectin Glycerosomes

Modulation of endoplasmic reticulum stress–induced insulin resistance by the low-carbohydrate high-fat ketogenic diet