Chemical Defenses | List of Frontiers open access articles

Review

Published on 11 Nov 2025

Bidirectional regulation of lipid metabolism and the tumor microenvironment: new perspectives from mechanism to therapy

in Cancer Immunity and Immunotherapy

Kaixin Shi
Bing Pan
Ruixin Zheng
Kaiyi Liu
Jincheng Song
Xiaobo Wang
Li Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1696102

321 views

Review

Published on 11 Nov 2025

Cellular senescence in the innervated niche modulates cancer-associated pain: an emerging therapeutic target?

in Cancer Immunity and Immunotherapy

Fabrizio Antonangeli
Edoardo Arcuri
Angela Santoni

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694567

479 views

Original Research

Published on 11 Nov 2025

Protocatechuic aldehyde ameliorates high glucose-induced podocyte injury by attenuating inflammation, oxidative stress, and apoptosis via suppression of endoplasmic reticulum stress through the GSK3β/Nrf2 pathway

in Cellular Biochemistry

Yishu Wang
Haifeng Wang
Yang Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1693955

303 views

Systematic Review

Published on 11 Nov 2025

Astragalus polysaccharides combined with radiochemotherapy for cervical cancer: a systematic review and meta-analysis of randomized controlled studies

in Pharmacology of Anti-Cancer Drugs

Tao Sun
Ruping Zhao
Yaling Zhang
Dongdong Li
Xishen Shan
Xiaoyu Tang
Yuling Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1699902

377 views

Opinion

Published on 11 Nov 2025

Tumor-cell HLA-DR expression as a potential biomarker of immunotherapy response in hepatocellular carcinoma

in Cancer Genetics

Xinping Wang
Ningning Mao

Frontiers in Oncology

doi 10.3389/fonc.2025.1700181

264 views

Case Report

Published on 11 Nov 2025

Accidental cannabis intoxication in two young children: clinical presentation and toxicokinetics - a case series

in Obstetric and Pediatric Pharmacology

Alessia Cafaro
Federica Pigliasco
Sebastiano Barco
Ilaria Negro
Emanuela Piccotti
Luca Manfredini
Samir Mahameed
Roberto Bandettini
Carla Debbia
Francesca Mattioli

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695194

463 views

Clinical Trial

Published on 11 Nov 2025

Pre-existing cardiovascular disease and hyperlipidemia and mortality in peritoneal dialysis patients

in Cardiovascular Endocrinology

Panpan Cao
Xiaojiang Zhan
Yueqiang Wen
Xiaoran Feng
Fenfen Peng
Xianfeng Wu
Xiaoyang Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1693668

502 views

Policy and Practice Reviews

Published on 11 Nov 2025

A responsive governance path to health equity: the role of state-led public interest litigation in China

in Life-Course Epidemiology and Social Inequalities in Health

Fei Qi
Bin Yu

Frontiers in Public Health

doi 10.3389/fpubh.2025.1701396

587 views

Review

Published on 11 Nov 2025

From pathogenic mechanisms to therapeutic perspectives: a review of gut microbiota and intestinal mucosal immunity in inflammatory bowel disease

in Mucosal Immunity

Tianqi Han
Yiwen Zhang
Gang Zheng
Yi Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1704651

668 views

Original Research

Published on 11 Nov 2025

Albumin coatings for counteracting uremic metabolites effects on host responses to biomaterials

in Biomaterials

Indu Sharma
Mehdi Ghaffari Sharaf
Aishwarya Pawar
Ethan Lockwood
Larry D. Unsworth

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1704352

693 views

Original Research

Published on 11 Nov 2025

Genetic knockdown of DYRK1A attenuates cognitive impairment, Aβ pathology, tauopathy and neuroinflammatory responses in mouse models of AD

in Multiple Sclerosis and Neuroimmunology

Hyun-ju Lee
Sora Kang
Yoo Jin Lee
Seokjun Oh
Bitna Joo
Jeong-Woo Hwang
Jeongseop Kim
Tae-Eun Kim
Tae-Mi Jung
Yu-Jin Kim

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661791

395 views

Case Report

Published on 11 Nov 2025

Case Report: Adolescent epididymal cysts: three management approaches including a rare synchronous epididymal cyst and testicular torsion

in Pediatric Urology

Qichao Xu
Cancan You
Jianhong Wu
Qiongzhang Xia
Congde Chen
Liguang Xia

Frontiers in Surgery

doi 10.3389/fsurg.2025.1660670

296 views

Brief Research Report

Published on 11 Nov 2025

Research on the acceptance of ICT among university students in Hong Kong—an empirical analysis based on the extended innovation diffusion theory

in Higher Education

Shuhua Mei
Anantawikrama Tungga Atmadja
Luh Putu Artini
Putu Indah Rahmawati

Frontiers in Education

doi 10.3389/feduc.2025.1658807

454 views

Mini Review

Published on 11 Nov 2025

Sex differences in G protein-coupled estrogen receptor-mediated mechanisms in preclinical models of anxiety and fear

in Behavioral Endocrinology

AnBinh S. Tran
Lisa Y. Maeng

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1655725

678 views

Systematic Review

Published on 11 Nov 2025

Neural correlates of uncertainty processing: meta-analysis of fMRI studies

in Decision Neuroscience

Andrey Timashkov
Sarah Anderson
Oksana Zinchenko

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1662272

844 views

Original Research

Published on 11 Nov 2025

Evaluating soil cover strategies for enhancing water conservation, biomass contribution, and weed control in rocoto pepper (Capsicum pubescens Ruiz & Pav.) cultivation under arid conditions

in Field Water Management

Russell Poma-Chamana
Elick Cama-Moreno
Ricardo Flores-Marquez
Antony Quello
Richard Solórzano

Frontiers in Agronomy

doi 10.3389/fagro.2025.1663633

691 views

Articles

Bidirectional regulation of lipid metabolism and the tumor microenvironment: new perspectives from mechanism to therapy

Cellular senescence in the innervated niche modulates cancer-associated pain: an emerging therapeutic target?

Protocatechuic aldehyde ameliorates high glucose-induced podocyte injury by attenuating inflammation, oxidative stress, and apoptosis via suppression of endoplasmic reticulum stress through the GSK3β/Nrf2 pathway

Astragalus polysaccharides combined with radiochemotherapy for cervical cancer: a systematic review and meta-analysis of randomized controlled studies

Tumor-cell HLA-DR expression as a potential biomarker of immunotherapy response in hepatocellular carcinoma

Accidental cannabis intoxication in two young children: clinical presentation and toxicokinetics - a case series

Pre-existing cardiovascular disease and hyperlipidemia and mortality in peritoneal dialysis patients

A responsive governance path to health equity: the role of state-led public interest litigation in China

From pathogenic mechanisms to therapeutic perspectives: a review of gut microbiota and intestinal mucosal immunity in inflammatory bowel disease

Albumin coatings for counteracting uremic metabolites effects on host responses to biomaterials

Genetic knockdown of DYRK1A attenuates cognitive impairment, Aβ pathology, tauopathy and neuroinflammatory responses in mouse models of AD

Case Report: Adolescent epididymal cysts: three management approaches including a rare synchronous epididymal cyst and testicular torsion

Research on the acceptance of ICT among university students in Hong Kong—an empirical analysis based on the extended innovation diffusion theory

Sex differences in G protein-coupled estrogen receptor-mediated mechanisms in preclinical models of anxiety and fear

Neural correlates of uncertainty processing: meta-analysis of fMRI studies

Evaluating soil cover strategies for enhancing water conservation, biomass contribution, and weed control in rocoto pepper (Capsicum pubescens Ruiz & Pav.) cultivation under arid conditions